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Cyclo(RGDyK)
Catalog No. A21819 αVβ3 integrin inhibitorCyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM. Learn More -
Carotegrast
Catalog No. A21997 α4 integrin receptor inhibitorCarotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities. Learn More -
ATN-161 trifluoroacetate salt
Catalog No. A21412 integrin α5β1 antagonistATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model. Learn More -
ATN-161
Catalog No. A21307 integrin α5β1 antagonistATN-161 is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model. Learn More -
MK-0429
Catalog No. A21173 αvβ3 integrin antagonistMK-0429 (L-000845704) is an orally active, potent, selective and nonpeptide αvβ3 integrin antagonist with an IC50 of 80 nM. Learn More -
Integrin Antagonists 27
Catalog No. A20895 integrin αvβ3 antagonistIntegrin Antagonists 27 is a small molecule integrin αvβ3 antagonist with binding affinity of 18 nM, as s novel anticancer agent. Learn More -
GLPG0187
Catalog No. A13423 Integrin receptor antagonistGLPG0187 is a broad spectrum integrin receptor antagonist with antitumor activity; inhibits αvβ1-integrin with an IC50 of 1.3 nM. Learn More -
BIO-1211
Catalog No. A17210 Integrin alpha4beta1 inhibitorBIO-1211 is an integrin alpha4beta1 inhibitor. Learn More -
R-BC154
Catalog No. A17184 α4β1/α9β1 inhibitorR-BC154 is a high affinity fluorescent α4β1/α9β1 inhibitor. Learn More -
Obtustatin
Catalog No. A17185 α1β1 inhibitorHighly potent integrin α1β1 inhibitor (IC50 = 0.8 nM for α1β1 binding to type IV collagen). Selective for α1β1 over α2β1, αIIbβ3, αvβ3, α4β1, α5β6, α9β1 and α4β7. Inhibits FGF2-stimulated angiogenesis in the chicken chorioallantoic model. Displays antitumor efficacy in a synergistic mouse model of Lewis lung carcinoma; blocks human melanoma growth in nude mice. Learn More -
TCS2314
Catalog No. A17193 Integrin InhibitorTCS2314 is a integrin very late antigen-4 (VLA-4; α4β1) antagonist with IC50 value of 4.4 nM. Learn More -
BTT-3033
Catalog No. A17200 -
BOP sodium salt
Catalog No. A17201 α9β1/α4β1 integrin inhibitorBOP sodium salt is a novel dual alpha9beta1/alpha4beta1 integrin inhibitor. Learn More -
Zaurategrast (CDP323)
Catalog No. A11614 VCAM-1 antagonistCDP323 is a small-molecule prodrug antagonist of the vascular cell adhesion molecule 1 binding to ??4-integrins Learn More -
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TR-14035
Catalog No. A17118 Integrin AntagonistTR-14035 is a dual antagonist of α4β7 and α4β1 integrins. Learn More -
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A-205804
Catalog No. A13047 Integrin InhibitorA-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 with IC50 value of 20 nM and 25 nM, respectively. Learn More -
CWHM12
Catalog No. A15967 αV integrins inhibitorCWHM 12 can suppress all 5 alpha V integrins. CWHM12 not only worked the same way to prevent fibrosis as the genetic deletion method, it also prevent the progression of existing fibrosis in the liver and lungs and reversed some of the damage caused by fibrosis to those organs. Learn More -
Cyclo (RGDyK) trifluoroacetate
Catalog No. A15918 Integrin inhibitorCyclo(RGDyK) trifluoroacetate is a potent and selective alphaVbeta3 integrin inhibitor with IC50 of 20 nM. Learn More -
E7820
Catalog No. A15456 lpha-2-integrin inhibitorE7820 is a small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells. Learn More -
RGD (Arg-Gly-Asp) Peptides
Catalog No. A15538 Inhibits integrin binding to RGD motifsRGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins. Learn More -
Cyclo (-RGDfK)
Catalog No. A14923 αvβ3 integrin inhibitorCyclo (-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin. Learn More -
Leukadherin 1
Catalog No. A13968 Integrin agonistLeukadherin 1 is an allosteric activator of CD11b/CD18. Increases CD11b/CD18-dependent cell adhesion to fibrinogen (EC50 = 4 μM). Learn More -
Pyrintegrin
Catalog No. A12876 Pyrintegrin is a cell-permeable small molecule that promotes human embryonic stem cell (hESC) survival by > 30-fold. Learn More -
Firategrast (SB 683699)
Catalog No. A12787 α4β1/α4β7 integrin antagonistFirategrast is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist designed to reduce trafficking of lymphocytes into the central nervous system (CNS). Learn More -
Cilengitide trifluoroacetate
Catalog No. A12371 Integrin inhibitorCilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. Learn More -
Cilengitide
Catalog No. A12372 Integrin inhibitorCilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis. Learn More
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