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Zaurategrast (CDP323)

Catalog No.: A11614

VCAM-1 antagonist

Zaurategrast (CDP323)

Zaurategrast (CDP323) Chemical Structure

CAS NO. 455264-31-0

CDP323 is a small-molecule prodrug antagonist of the vascular cell adhesion molecule 1 binding to ??4-integrins

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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Mustafa Ahmadzai, .et al. Integrins are Mechanosensors That Modulate Human Eosinophil Activation, Front Immunol, 2015, 6: 525 PMID: 26539194

Biological Activity

CDP323 is a small-molecule prodrug antagonist of the vascular cell adhesion molecule 1 binding to ??4-integrins
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.18 mL 95.89 mL 191.79 mL
0.5 mM 3.84 mL 19.18 mL 38.36 mL
1 mM 1.92 mL 9.59 mL 19.18 mL
5 mM 0.38 mL 1.92 mL 3.84 mL

*The above data is based on the productmolecular weight 521.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11614
Actions Antagonist
CAS No. 455264-31-0
Formula C26H25BrN4O3
M. Wt 521.41
Purity >98%
Synonyms CDP-323;CDP 323;CDP323
SMILES C1CCC2(CC1)C(=C(C2=O)Br)N[[email protected]@H](CC3=CC=C(C=C3)NC4=NC=CC5=C4C=NC=C5)C(=O)O

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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