Cilengitide

Catalog No.: A12372

Integrin inhibitor

Cilengitide

Cilengitide Chemical Structure

CAS NO. 188968-51-6

Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $120.00

Special Price $96.00

10 mg

Regular Price: $180.00

Special Price $144.00

25 mg

Regular Price: $320.00

Special Price $256.00

50 mg

Regular Price: $550.00

Special Price $440.00

10mM * 1mL in DMSO
$200.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

Cilengitide is a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
In vitro (25°C) DMSO 100 mg/mL (169.87 mM)
Water 8 mg/mL (13.59 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.99 mL 84.94 mL 169.88 mL
0.5 mM 3.4 mL 16.99 mL 33.98 mL
1 mM 1.7 mL 8.49 mL 16.99 mL
5 mM 0.34 mL 1.7 mL 3.4 mL

*The above data is based on the productmolecular weight 588.66. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A12372
Actions No
M. Wt 588.66
Formula C27H40N8O7
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 188968-51-6
Synonyms EMD 12197,EMD-85189,EMD-121974,NSC-707544,D03497
SMILES CC(C)[[email protected]]1C(=O)N[[email protected]](C(=O)NCC(=O)N[[email protected]](C(=O)N[[email protected]@H](C(=O)N1C)CC2=CC=CC=C2)CC(=O)O)CCCN=C(N)N

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