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$0.00 IRAK
Interleukin-1 receptor-associated kinases (IRAKs) are key components in the signal transduction pathways utilized by interleukin-1 receptor (IL-1R), interleukin-18 receptor (IL-18R), and Toll-like receptors (TLRs).
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IRAK inhibitor 1
Catalog No. A11455 IRAK-4 inhibitorIRAK inhibitor 1 is a potent IRAK-4 inhibitor with IC50 of 216 nM, is poorly active against JNK-1 and JNK-2 with IC50 of 3.801 μM, and >10 μM, respectively. Learn More -
IRAK inhibitor 3
Catalog No. A11457 IL-1 receptor-associated kinase (IRAK) kinase modulatorIRAK inhibitor 3 is an interleukin-1 (IL-I) receptor-associated kinase (IRAK) kinase modulator extracted from patent WO2008030579 A2. Learn More -
IRAK inhibitor 4
Catalog No. A11458 IRAK4 inhibitorIRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4(IRAK4) inhibitor. Learn More -
AZ1495
Catalog No. A19512 IRAK4 inhibitorAZ1495 (compound 28) is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. Learn More -
IRAK4-IN-1
Catalog No. A19572 IRAK4 inhibitorIRAK4-IN-1 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor with an IC50 of 7 nM. Learn More -
IRAK4-IN-4
Catalog No. A22333 IRAK4 inhibitorIRAK4-IN-4 is an interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor extracted from patent CN107163044A, Compound15, has an IC50 of 2.8 nM. Learn More -
JNK-IN-7
Catalog No. A15136 JNK InhibitorJNK-IN-7 is a relatively selective JNKs inhibitor(IC50= 1.54/1.99/0.75 for JNK1/2/3); also bound to IRAK1, PIK3C3, PIP5K3 and PIP4K2C. Learn More -
IRAK-1-4 Inhibitor I
Catalog No. A11462 IRAK-1-4 inhibitor is a benzimidazole that disrupts the activity of IRAK-1 and -4 with IC50 values of 300 and 200 nM, respectively. Learn More -
IRAK inhibitor 6 (IRAK-IN-6)
Catalog No. A11460 IRAK inhibitorIRAK-IN-6, also known as IRAK inhibitor 6, is an interleukin-1 receptor associated kinase 4 (IRAK-4) inhibitor. IRAK-4 is reported to be essential for the activation of the intracellular signalling cascades including NF-kB and MAPK pathways, which are critical for the production of inflammatory cytokines. Learn More -
CA-4948
Catalog No. A17005 IRAK4 inhibitorCA-4948 is a potent, and orally active interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor. CA-4948 exhibited the greatest efficacy in four of the five ABC-DLBCL PDX models tested as compared to GBC-DLBCL and ABC/GCB DLBCL PDX models. Learn More -
PF-06650833
Catalog No. A17187 IRAK4 inhibitorPF-06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4). Learn More -
AS 2444697
Catalog No. A17186 IRAK4 inhibitorAS-2444697 is a potent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor with IC50 value of 21 nM. Learn More
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