Keap1-Nrf2

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  1. Oltipraz

    Catalog No. A13164
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    Nrf2 activator
    Oltipraz inhibits HIF-1alpha activity and HIF-1alpha-dependent tumor growth, which may result from a decrease in HIF-1alpha stability through S6K1 inhibition in combination with an H2O2-scavenging effect. Learn More
  2. CDDO-EA

    Catalog No. A16299
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    Nrf2 activator
    CDDO-EA is an activator of Nrf2/ARE; Neuroprotective effect. Learn More
  3. NK-252

    Catalog No. A16300
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    Nrf2 activator
    NK-252 is a Nrf2 activator, exhibits a greater Nrf2-activating potential than OPZ. Learn More
  4. RTA-408

    Catalog No. A14417
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    Nrf2 inhibitor
    RTA-408 is a synthetic triterpenoid that potently activates the antioxidative transcription factor Nrf2 and inhibits the proinflammatory transcription factor NF-kB. Learn More
  5. Brusatol

    Catalog No. A16893
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    Nrf2 inhibitor
    Brusatol is a biochemical, isolated from the Brucea javanica plant, that inhibits Nrf2. Learn More
  6. ML-385

    Catalog No. A17172
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    NRF2 inhibitor
    ML-385 is an inhibitor of nuclear factor erythroid 2-related factor 2 (Nrf2) with IC50 value of 1.9 μM. Learn More

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