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Oltipraz
Catalog No. A13164 Nrf2 activatorOltipraz inhibits HIF-1alpha activity and HIF-1alpha-dependent tumor growth, which may result from a decrease in HIF-1alpha stability through S6K1 inhibition in combination with an H2O2-scavenging effect. Learn More -
CDDO-EA
Catalog No. A16299 -
NK-252
Catalog No. A16300 Nrf2 activatorNK-252 is a Nrf2 activator, exhibits a greater Nrf2-activating potential than OPZ. Learn More -
AKBA
Catalog No. A17908 Nrf2 activatorAKBA (Acetyl-11-keto-β-boswellic acid) is an active triterpenoid compound from the extract of Boswellia serrate and a novel Nrf2 activator. Learn More -
Nrf2-IN-1
Catalog No. A12561 Nrf2 inhibitorNrf2-IN-1 (Compound 4f) is an inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2), acts as a promising agent in acute myeloid leukemia (AML) therapy. Learn More -
(R)-Sulforaphane
Catalog No. A21690 Keap1/Nrf2/ARE pathway inducer(R)-Sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway. (R)-Sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Learn More -
RTA-408
Catalog No. A14417 Nrf2 inhibitorRTA-408 is a synthetic triterpenoid that potently activates the antioxidative transcription factor Nrf2 and inhibits the proinflammatory transcription factor NF-kB. Learn More -
Brusatol
Catalog No. A16893 Nrf2 inhibitorBrusatol is a biochemical, isolated from the Brucea javanica plant, that inhibits Nrf2. Learn More -
ML-385
Catalog No. A17172 NRF2 inhibitorML-385 is an inhibitor of nuclear factor erythroid 2-related factor 2 (Nrf2) with IC50 value of 1.9 μM. Learn More
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