Anti-infectives

Cat. No.

A13950

CAS No.

160369-85-7

X-Neu5Ac sodium

Synonyms: X-NeuNAc

X-Neu5Ac sodium is a neuraminidase substrate that facilitates the chromogenic assay of neuraminidase activity in bacterial expression systems. This compound has a Km value of 0.89 mM for neuraminidase, making it an effective tool for studying neuraminidase function and inhibition. Its use in research applications provides insights into bacterial mechanisms and potential therapeutic targets for bacterial infections.

Cat. No.

A33189

CAS No.

1955-26-6

UDP-rhamnose

UDP-rhamnose is the activated form of rhamnose that plays a crucial role in the synthesis of rhamnose-containing glycans in fungi. This nucleotide sugar acts as a key substrate for glycosyltransferases, enabling the assembly of polysaccharides involved in the fungal cell wall. UDP-rhamnose is utilized in research focused on understanding fungal pathogenesis and the development of therapeutics for fungal infections.

Cat. No.

A44561

CAS No.

129572-48-1

X-GalNAc

X-GalNAc is a chromogenic substrate that specifically targets N-acetyl-β-galactosidase. This reagent is utilized in molecular biology to detect the presence of cloned DNA inserts in bacterial colonies cultured on agar plates. The enzymatic hydrolysis of X-GalNAc results in a distinct color change, facilitating easy identification of recombinant bacterial clones in various genetic research applications.

Cat. No.

A46369

CAS No.

1380078-95-4

Plazomicin sulfate

Synonyms: ACHN 490 sulfate

Plazomicin sulfate is a semi-synthetic aminoglycoside antibiotic that primarily targets bacterial ribosomes to disrupt protein synthesis. It functions as a substrate for aminoglycoside acetyltransferase and aminoglycoside phosphotransferase while remaining unmodified by several common aminoglycoside-modifying enzymes. Plazomicin sulfate exhibits selective inhibition of MATE2-K and demonstrates significant efficacy against multidrug-resistant bacteria, including carbapenem-resistant Enterobacterales. This compound is valuable for research applications focusing on antibiotic resistance and the mechanisms of action of aminoglycosides.

Cat. No.

A46882

CAS No.

162478-50-4

Aurantimycin A

Aurantimycin A is a depsipeptide antibiotic that targets Gram-positive bacteria, demonstrating potent antimicrobial activity. As a substrate of the LieAB transporter, it facilitates the study of bacterial resistance mechanisms and transporter functions. This compound is valuable for research in antibiotic development and microbial pathogenesis.

Cat. No.

A47768

CAS No.

80394-72-5

Oxanosine

Oxanosine is an antibiotic derived from the Streptomyces MG265-CF34 strain, exhibiting notable anti-tumor properties. This compound functions as a substrate for adenosine deaminase, highlighting its potential utility in various research applications related to microbial activity and cancer treatment. Its unique biochemical interactions make it a valuable reagent for studies in antibiotic development and tumor biology.

Cat. No.

A48377

CAS No.

3577-01-3

Cefaloglycin

Synonyms: Cephaloglycin

Cefaloglycin is a nephrotoxic β-lactam cephalosporin antibiotic that exhibits significant antibacterial activity, specifically targeting Gram-positive cocci, excluding enterococci. Its mechanism involves inhibition of bacterial cell wall synthesis, making it effective in clinical settings requiring treatment of specific bacterial infections. Additionally, Cefaloglycin has been shown to interfere with mitochondrial substrate uptake and respiration, adding to its profile as a compound of interest in biochemical and pharmacological research.

Cat. No.

A48916

CAS No.

58471-53-7

Di-aspartic acid

Di-aspartic acid (Aspartylaspartate) serves as a growth substrate for several bacterial species, including Porphyromonas gingivalis, Prevotella intermedia, Prevotella nigrescens, and Fusobacterium nucleatum. Its ability to support the growth of these bacteria makes it a valuable tool in microbiological research, particularly in studies related to periodontal disease and oral microbiome dynamics.

Cat. No.

A49622

CAS No.

41952-52-7

Cefcanel

Cefcanel is an orally active cephalosporin antibiotic targeting bacterial cell wall synthesis. It exhibits effective antibacterial activity against methicillin-susceptible strains of Staphylococcus aureus and Staphylococcus epidermidis, as well as Haemophilus influenzae and Moraxella catarrhalis. Cefcanel serves as a substrate for hydrolysis by various beta-lactamases, including TEM-1, TEM-3, and Moraxella Bro-1, making it a valuable tool for research on antibiotic resistance mechanisms and bacterial susceptibility testing.

Cat. No.

A50729

CAS No.

410532-55-7

2A/2B Dengue protease substrate

2A/2B Dengue protease substrate (Ac-RTSKKR-pNA) is a polypeptide substrate designed for the Dengue NS2B-NS3 protease. This substrate facilitates the understanding of protease activity by serving as a valuable tool in the development of selective inhibitors targeting the Dengue NS2B-NS3 protease. Its efficacy in research applications enhances the study of dengue virus pathogenesis and potential therapeutic strategies.

Cat. No.

A50737

CAS No.

410532-54-6

Ac-EVKKQR-pNA

Ac-EVKKQR-pNA is a competitive chromogenic para-nitroanilide substrate designed to probe the NS2B-NS3 cleavage site. This reagent includes a readily hydrolyzable para-nitroanilide at the P1’ position, enhancing its reactivity. It is primarily used in studies of dengue virus type 2 and other flavivirus infections, facilitating the exploration of viral protease activity and potential therapeutic interventions.

Cat. No.

A51454

CAS No.

1426174-10-8

Fluorescent HIV Substrate

Fluorescent HIV Substrate is specifically designed to facilitate the study of HIV protease activity. This highly sensitive substrate emits fluorescence upon cleavage by the HIV protease, enabling real-time monitoring of enzymatic activity. It serves as an essential tool in HIV research, helping to evaluate protease inhibitors and advance therapeutic strategies against HIV infection.

Cat. No.

A51828

CAS No.

128340-47-6

HIV Protease Substrate IV

HIV Protease Substrate IV is a specific substrate designed for HIV protease. It facilitates the quantitative assessment of HIV-1 protease activity, enabling researchers to study the enzyme's function and evaluate potential inhibitors. This substrate is particularly useful in the development of antiviral therapies targeting HIV protease, contributing to the understanding of HIV pathogenesis and treatment strategies.

Cat. No.

A51831

CAS No.

149639-49-6

HIV-1, HIV-2 Protease Substrate

HIV-1, HIV-2 Protease Substrate is a specific substrate designed for the enzymatic activity of HIV-1 and HIV-2 proteases. This substrate contains four residues that allow for conservative substitutions, facilitating studies on substrate binding and protease activity. It is a valuable tool for research focused on HIV protease function and the development of antiviral therapies.

Cat. No.

A51842

CAS No.

223769-59-3

HIV Protease Substrate 1

HIV Protease Substrate 1 is a fluorogenic substrate specifically designed for the study of HIV protease activity. This reagent allows for the quantitative assessment of enzymatic function, facilitating investigations into HIV protease inhibitors and their effects on viral replication. It is particularly useful in the development of antiviral therapies and for studying the proteolytic processing of HIV proteins.

Cat. No.

A51844

CAS No.

124077-63-0

HIV Protease Substrate I

HIV Protease Substrate I is a chromogenic substrate specifically designed for the HIV-1 protease. It contains the optimal cleavage site recognized by the enzyme, enabling accurate assessment of protease activity. This substrate is valuable for studying HIV-1 protease function and kinetics, as well as for evaluating the efficacy of protease inhibitors in research applications.

Cat. No.

A51852

CAS No.

130877-92-8

Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2

Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate specifically designed for assessing the activity of HIV-1 protease. This compound exhibits a strong interaction with the enzyme, facilitating the measurement of protease activity in research applications related to HIV-1 pathogenesis and antiviral drug development. Its utility in protease assays makes it a valuable tool for studying HIV-1 enzymatic function and evaluating potential therapeutic interventions.

Cat. No.

A89708

CAS No.

474644-34-3

VLPA-GlcNAc

VLPA-GlcNAc is a chromogenic glucosaminide substrate that serves as a valuable tool for the identification of Candida species. It can be utilized in the preparation of specialized agar media, facilitating the differentiation of Candida strains based on their enzymatic activity. This reagent is essential in microbiological research and diagnostics, particularly in clinical settings where rapid identification of fungal pathogens is crucial.

Cat. No.

A91421

CAS No.

341972-94-9

5-Bromo-4-chloro-3-indolyl-α-D-maltotrioside

5-Bromo-4-chloro-3-indolyl-α-D-maltotrioside functions as a sensitive enzyme substrate with chemiluminescent properties. It facilitates the detection of various enzymatic activities, making it suitable for diagnostic assays aimed at identifying bacterial and fungal infections, as well as other diseases. Its utility in research applications enhances the reliability of assays in clinical microbiology and molecular diagnostics.