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Neuropeptide S receptor (NPSR) ligands are research compounds for a neuronal G protein-coupled receptor. Receptor signaling is associated with intracellular second messengers and is studied in arousal, stress responses and neural circuit function. ML154 is listed as an antagonist, while R06039-691 and R06039-641 are annotated as agonists. The category also includes other receptor-related modulators. Differences in the listed functional classes provide context for selecting compounds when examining receptor pharmacology and downstream signaling in experimental systems.
NPSR1 modulator-1 is a selective modulator of the neuropeptide S receptor 1 (NPSR1), influencing its signaling pathways. This compound exhibits potential biological activity in regulating stress response and anxiety-related behaviors. It is primarily utilized in research focusing on neuropharmacology and the development of therapeutic strategies for anxiety disorders.
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