Prostanoid Receptors

Cat. No.

A63157

CAS No.

330589-21-4

8-Iso prostaglandin E2 isopropyl ester

8-Iso Prostaglandin E2 isopropyl ester is a derivative of 8-iso Prostaglandin E2, designed to enhance lipophilicity compared to its free acid counterpart. This compound exhibits significant biological activity, primarily functioning as a modulator of various signaling pathways involved in inflammation and cellular responses. It is commonly utilized in research applications to investigate the roles of prostaglandins in physiological and pathological processes.

Cat. No.

A63253

CAS No.

36950-85-3

20-ethyl Prostaglandin F2α

Synonyms: ICI 74205; 20-ethyl PGF2α

20-ethyl Prostaglandin F2α is a synthetic analog of Prostaglandin F2α, functioning as a potent modulator of the prostaglandin pathway. It exhibits key biological activities, including contraction of smooth muscle and regulation of vascular tone. This compound is widely used in research applications related to reproductive biology, cardiovascular studies, and inflammation.

Cat. No.

A63356

CAS No.

284464-83-1

BM-573

BM-573 is an orally active dual thromboxane A₂ (TXA₂) modulator that functions through specific inhibition of thromboxane synthase (TxAS) and antagonism of thromboxane receptors (TP). With an IC50 of 1.3 nM, it effectively inhibits platelet aggregation induced by arachidonic acid or TXA₂ analogues without affecting cyclooxygenase enzymes (COX-1/COX-2), thus preserving other prostaglandin syntheses. BM-573 also demonstrates a significant inhibitory effect on U-46619-induced contractions in rat gastric fundus smooth muscle. This compound is valuable for research applications in atherosclerosis, myocardial infarction, pulmonary hypertension, and shock.

Cat. No.

A63361

CAS No.

189278-12-4

Proquinazid

Proquinazid is a Bcl-2 and PCNA modulator that acts as an oxidative stress inducer. It is known to induce genotoxic effects and promote apoptosis by influencing the balance of pro-apoptotic and anti-apoptotic proteins. This compound is utilized in research applications focusing on cellular responses to DNA damage and apoptosis mechanisms.

Cat. No.

A63371

CAS No.

26771-94-8

Prostaglandin A1 methyl ester

Synonyms: PGA1 methyl ester

Prostaglandin A1 methyl ester is a cyclopentenone analog that functions primarily as a modulator of inflammatory processes. It exhibits significant biological activity as an inducer of apoptosis and a potent anti-inflammatory agent. This compound is widely used in research applications focused on inflammation, cancer biology, and the study of prostaglandin pathways.