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AhR antagonist
CH-223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor.- Jie Tang, .et al. , Arch Toxicol, 2025, Nov;99(11):4611-4629 PMID: 40835755
- Yukiko Sakakibara, .et al. , Biopharm Drug Dispos, 2022, Oct;43(5):175-182 PMID: 36000181
- Jie Tang, .et al. , Ecotoxicol Environ Saf, 2021, Sep 15;221:112423 PMID: 34146985
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AhR antagonist
StemRegenin 1 (SR1) is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs). -
AHR antagonist
BAY 2416964 is a potent and orally active aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2018146010A1, example 192, has an IC50 of 341 nM. BAY 2416964 has the potential for solid tumors treatment. -
AHR antagonist
AHR antagonist 1 is an aryl hydrocarbon receptor (AHR) antagonist extracted from patent WO2017202816A1, example 23, has an IC50 of 39.9 nM in human cell line.
