Catalog No.
Product Name
Application
Product Information
Citations
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Anti-inflammatory Agent
Betamethasone-17-butyrate-21-propionate is a potent anti-inflammatory agent primarily used in the treatment of inflammatory skin conditions. This synthetic corticosteroid acts by inhibiting the release of inflammatory mediators, thereby reducing erythema, swelling, and discomfort. Its efficacy makes it a valuable research tool for studying corticosteroid effects on skin inflammation and for evaluating therapeutic strategies in dermatological applications. -
Anti-inflammatory Agent
Bucloxic acid calcium is an anti-inflammatory agent classified as a pyrrazole derivative. It exhibits potent anti-inflammatory properties, making it suitable for research applications in chronic glomerular nephropathies. This compound can aid in the study of inflammatory processes and potential therapeutic interventions in kidney diseases. -
Anti-Inflammatory Agent
SM-8849 is a thiazole derivative characterized by its anti-inflammatory properties. This compound selectively targets and inactivates T cells associated with delayed-type hypersensitivity (DTH) reactions, effectively disrupting the key immunopathological processes implicated in arthritis while sparing humoral immune functions such as antibody synthesis. In a Type II Collagen-induced mouse model of arthritis, SM-8849 demonstrated significant efficacy by relieving clinical symptoms and mitigating bone destruction and joint damage. SM-8849 serves as a valuable reagent for research on autoimmune diseases, particularly rheumatoid arthritis. -
Anti-inflammatory Agent
HMR-4011A is a chemically modified derivative of Contignasterol, functioning as an orally active anti-inflammatory agent. It exhibits significant efficacy in reducing inflammation and has potential applications in respiratory research, particularly in the context of asthma. HMR-4011A offers valuable insights for studies focused on inflammatory pathways and therapeutic interventions. -
Anti-Inflammatory Agent
Mofebutazone is a monophenyl analogue of Phenylbutazone, functioning primarily as an anti-inflammatory agent. It exhibits potent anti-inflammatory activity and is utilized in research related to asthma and other inflammatory conditions. Its oral bioavailability makes it a valuable tool for studying the therapeutic effects of anti-inflammatory compounds in various biological models. -
Anti-inflammatory Agent
Stemospironine is an alkaloid derived from plants of the genus Hyacinth, functioning primarily as an anti-inflammatory agent. It exhibits significant biological activity as a cough suppressant while also serving as a valuable tool for investigating various inflammatory conditions. Its potential applications in research include exploring mechanisms of inflammation and evaluating therapeutic strategies for related diseases. -
Anti-Inflammatory Agent
1-beta-D-Arabinofuranosyluracil is an anti-inflammatory agent derived from the Caribbean sponge Tectitethya crypta. This compound exhibits a range of biological activities, including anti-inflammatory effects, analgesic properties, and vasodilation. Additionally, it has been shown to inhibit the proliferation of mouse lymphoma cells, making it a valuable reagent for research in cellular biology and inflammation studies. -
Anti-inflammatory Agent
Lonchocarpic acid acts as an anti-inflammatory agent, targeting pathways involved in neuroinflammation. It has demonstrated efficacy in models of LPS- or poly(I:C)-induced neuroinflammation, suggesting potential applications in investigating neuroinflammatory conditions. This compound is useful for researchers exploring the molecular mechanisms of inflammation and developing therapeutic strategies for related disorders. -
Anti-inflammatory Agent
Epmedin C is an orally active anti-inflammatory agent and immunomodulator that targets multiple key proteins, including UCP1, Caspase-1, CDK2, and Keap1. This compound effectively inhibits epithelial cell proliferation by disrupting the CDK2/Cyclin E complex, while also upregulating Nrf2 expression, reducing reactive oxygen species levels, and inhibiting the secretion of pro-inflammatory cytokines. Through these mechanisms, Epmedin C aids in restoring antibody production and alleviating tissue damage, making it relevant for research on conditions such as obesity, immunotoxicity induced by Deoxynivalenol, and mammary hyperplasia. -
Anti-inflammatory Agent
Saikosaponin A is an anti-inflammatory agent primarily derived from Bupleurum chinense. It effectively regulates lipid metabolism and promotes cholesterol efflux, making it relevant in early atherosclerosis research. Furthermore, Saikosaponin A acts as a potential agonist of peroxisome proliferator-activated receptor γ (PPAR-γ), significantly enhancing its expression. This compound is particularly useful in studies related to hyperlipidemic pancreatitis. -
Anti-inflammatory Agent
Physalin L is an anti-inflammatory agent that inhibits lipopolysaccharide (LPS)-induced nitric oxide (NO) production in macrophages, achieving an average inhibitory rate of 70.97%. This compound is valuable for research focused on inflammation pathways and can be utilized to investigate its potential therapeutic effects in various inflammatory conditions. -
Anti-inflammatory Agent
Chikusetsusaponin IVa is an orally active anti-inflammatory agent that targets YAP, demonstrating a binding affinity with a KD value of 0.388 mM. This compound effectively reduces the expression of inflammatory mediators such as IL-6, IL-10, and COX-2, while modulating nitric oxide production and promoting reactive oxygen species generation. Additionally, Chikusetsusaponin IVa induces apoptosis, inhibits MAPK and TAZ signaling pathways, and regulates Nrf2 and JAK/STAT pathways. It exhibits potential as an anti-H9N2 avian influenza virus agent and demonstrates anti-cancer properties, along with hepatoprotective and osteoprotective effects, making it a valuable tool for research in inflammation and cancer biology. -
Anti-inflammatory Agent
Praeruptorin A is an anti-inflammatory compound derived from Peucedanum praeruptorum. It demonstrates significant anti-inflammatory activity by inhibiting NF-κB activation, which is crucial for mediating inflammatory responses. This compound is valuable in research applications focused on inflammation-related signaling pathways and the development of anti-inflammatory therapies. -
Antiinflammatory Agent
Sodium gualenate is a hydrophilic derivative of guaiazulene that functions as an anti-inflammatory agent. It exhibits significant anti-inflammatory and wound-healing properties, making it useful in the treatment of conditions such as duodenal ulcers, gastric ulcers, and gastritis. This compound is valuable for research focused on gastrointestinal health and the modulation of inflammatory responses. -
Anti-inflammatory Compound
Methyl 2-acetoxybenzoate, also known as methyl acetylsalicylate, serves as a prodrug that exerts anti-inflammatory effects. Upon chemical or enzymatic hydrolysis, it converts to methyl 2-hydroxybenzoate, which is known for its analgesic properties. This compound is applicable in research pertaining to inflammatory diseases and can be utilized as an analgesic agent in topical formulations such as liniments. -
Anti-inflammatory Agent
6α-Fluoroprednisolone is an anti-inflammatory agent that serves as an internal standard for the analysis of methylprednisolone, prednisolone, and prednisone. This compound is essential for research applications related to congenital adrenal virilism and Addison's disease, aiding in the understanding of adrenal function and corticosteroid therapy. It is an invaluable tool for studies focused on steroid hormone action and metabolic regulation. -
Anti-Inflammatory Corticosteroid
Paramethasone is an anti-inflammatory corticosteroid that targets glucocorticoid receptors. It is known for its ability to reduce inflammation and modulate immune responses, making it valuable in the treatment of various inflammatory and autoimmune conditions. This compound is commonly utilized in research to investigate corticosteroid mechanisms and therapeutic applications in disorders such as asthma, arthritis, and other inflammatory diseases. -
Anti-inflammatory and Protein-Binding Inhibitor
4-Acetylaminoantipyrine is a derivative of antipyrine that functions primarily as an anti-inflammatory agent and a protein-binding inhibitor. It acts as a PGE2-dependent blocker and inhibits cyclooxygenase (COX), thereby modulating inflammatory pathways. Additionally, 4-acetylaminoantipyrine has the capability to inhibit Cu/Zn superoxide dismutase (Cu/ZnSOD) and can spontaneously bind with bovine serum albumin (BSA), resulting in conformational changes. This compound is valuable for research applications in inflammation and protein interaction studies. -
Pro-inflammatory Mediator Inhibitor
Heparin disaccharide III-S (trisodium) is a heparin-derived disaccharide that serves as a pro-inflammatory mediator inhibitor. It effectively inhibits the spontaneous secretion of interleukin-8 (IL-8) and interleukin-1 beta (IL-1β) in intestinal epithelial cells by acting at the post-translational level without affecting mRNA or intracellular mediator concentrations. This compound is useful for research on inflammatory responses and the regulation of cytokine secretion in intestinal models. -
Pro-inflammatory Mediator Inhibitor
Heparin disaccharide I-H (trisodium) is a heparin-derived disaccharide that acts as a pro-inflammatory mediator inhibitor. This compound effectively blocks the spontaneous secretion of IL-8 and IL-1β in intestinal epithelial cells at the post-translational level, while leaving mRNA expression levels and intracellular contents unaffected. Demonstrating dose-dependent anti-inflammatory activity, Heparin disaccharide I-H (trisodium) is valuable for research applications targeting intestinal inflammation and associated signaling pathways. -
Anti-inflammatory/Analgesic Agent
Nitraquazone is an anti-inflammatory and analgesic agent that inhibits phosphodiesterase, leading to increased intracellular levels of cyclic adenosine monophosphate (cAMP). This mechanism underlies its potential use in research focused on inflammation and pain management. Nitraquazone serves as a valuable tool in the investigation of anti-inflammatory pathways and analgesic effects in various biological contexts. -
Anti-inflammatory/tumor Agent
Hesperetin triacetate is a compound known for its anti-inflammatory and anti-tumor properties. It exerts its effects by inhibiting the denaturation of bovine serum albumin in vitro and reducing carrageenan-induced paw swelling in mouse models in vivo. Additionally, Hesperetin triacetate demonstrates anti-proliferative activity against breast cancer cells, inducing DNA degradation and apoptosis. This compound is suitable for research focused on breast cancer and inflammation mechanisms. -
Non-steroidal Anti-inflammatory Agent
Lotifazole is a non-steroidal anti-inflammatory agent that specifically inhibits delayed-type hypersensitivity without relying on the prostaglandin synthesis inhibition pathway at low doses. It demonstrates significant efficacy in reducing paw edema induced by carrageenan in rats, alleviating erythema caused by ultraviolet radiation in guinea pigs, and mitigating pleurisy at high doses. Lotifazole is valuable for research into T-cell-mediated diseases, providing insights into potential therapeutic strategies. -
Anti-Inflammatory Agent
Genipin 1-β-D-gentiobioside is an iridoid glycoside extracted from Gardenia jasminoides, exhibiting strong anti-inflammatory properties. This compound demonstrates hepatoprotective and antioxidant activities, making it valuable for research on liver health and inflammation-related pathways. Its antithrombotic effects also highlight its potential in cardiovascular studies. -
Anti-inflammatory Agent
Delmetacin is an anti-inflammatory agent that primarily targets cyclooxygenase enzymes, thereby inhibiting prostaglandin synthesis. This mechanism results in the reduction of inflammation and pain. Delmetacin is utilized in various research applications focused on inflammatory diseases and pain management, making it a valuable tool for understanding inflammatory pathways and developing new therapeutic strategies. -
Anti-Inflammatory Agent
Butin is a biologically active flavonoid primarily targeting anti-inflammatory pathways. Isolated from the heartwood of Dalbergia odorifera, Butin exhibits strong antioxidant and antiplatelet properties. It has been shown to significantly alleviate myocardial infarction symptoms, enhance cardiac function, and prevent diabetes-induced oxidative damage in the heart in rat models, making it a valuable compound for cardiovascular and metabolic research applications. -
Anti-Inflammatory Agent
11-O-Galloylbergenin is an anti-inflammatory agent derived from the ethanolic extract of Mallotus philippinensis. This compound exhibits significant analgesic and anti-inflammatory properties, making it a valuable tool for research related to pain management and inflammatory conditions. Its potential utility in therapeutic applications underscores its importance in pharmacological studies. -
Antiinflammatory Agent
Fenclozine dimaleate is a non-steroidal anti-inflammatory agent that primarily targets inflammatory pathways. It exhibits significant anti-inflammatory activity and is utilized in research to investigate various inflammatory conditions and their underlying mechanisms. Its potential applications include studying pain relief and reducing inflammation in both in vitro and in vivo models. -
Anti-Neuroinflammatory Agent
Fendleryl B is an anti-neuroinflammatory agent derived from the edible mushroom Gambas. This compound demonstrates significant potential in modulating neuroinflammatory responses, making it valuable for studying neurological diseases and related pathologies. Its ability to influence neuroinflammation positions it as a promising candidate for research in neurodegenerative disorders. -
anti-inflammatory agent
Lofemizole is a non-steroidal anti-inflammatory agent that inhibits the activity of cyclooxygenase enzymes, leading to a reduction in prostaglandin synthesis. This compound exhibits significant anti-inflammatory properties, making it valuable in the study of inflammatory diseases. Lofemizole can be utilized in research to explore therapeutic strategies for conditions characterized by chronic inflammation. -
Anti-inflammatory Compound
Triptoquinone H is an anti-inflammatory compound derived from the traditional Chinese medicine Tripterygium hypoglaucu. It exhibits significant cytotoxic, immunomodulatory, and anti-inflammatory activities, making it a valuable tool for studying cancer and inflammatory diseases. Researchers can utilize Triptoquinone H to explore its therapeutic potential and mechanisms in various biological contexts. -
Nonsteroidal Anti-inflammatory Drug
Clofenamic acid, a nonsteroidal anti-inflammatory drug, primarily targets cyclooxygenase enzymes (COX-1 and COX-2) to inhibit prostaglandin synthesis. It exhibits significant anti-inflammatory and analgesic properties, making it a useful tool for studying inflammatory processes. Clofenamic acid is particularly relevant in research related to rheumatoid arthritis and other inflammatory disorders. -
Anti-Inflammatory Agent
Broperamole is an anti-inflammatory agent that acts primarily by modulating inflammatory pathways. It exhibits both systemic and topical anti-inflammatory activity, making it a valuable tool for the investigation of inflammation-related disorders. This compound can be utilized in research applications focused on pain management and therapeutic interventions for inflammatory conditions. -
AntiInflammatory Agent
Coixol (6-Methoxy-2-benzoxazolinone; 6-MBOA) functions as a potent anti-inflammatory agent by reducing the expression of inducible nitric oxide synthase (iNOS). It effectively inhibits the production of pro-inflammatory cytokines, including TNF-α, IL-6, and IL-1β. Additionally, Coixol has been shown to enhance glucose tolerance and lower plasma insulin levels, contributing to a reduction in blood glucose levels. This compound is valuable for research applications focused on inflammation and metabolic disorders. -
Anti-inflammatory Agent
Phenylbutazone trimethylgallate serves as a non-steroidal anti-inflammatory agent with oral bioavailability. It exhibits significant anti-inflammatory properties, making it useful for the study of inflammatory pathways and conditions. This compound may be utilized in research to explore its mechanistic effects and potential therapeutic benefits in various inflammatory diseases. -
Anti-inflammatory Drug
Visnagin is an antioxidant furanocoumarin derivative that targets inflammatory pathways to exhibit significant anti-inflammatory and analgesic properties. It demonstrates strong potential in preventing cerulein-induced acute pancreatitis, making it relevant for studies of pancreatic inflammation. Additionally, visnagin displays notable vasodilator effects in vascular smooth muscle, suggesting its utility in cardiovascular research applications. -
Anti-inflammatory Agent
AIM-102 is an immune-modulating anti-inflammatory agent targeting pathways involved in inflammatory responses. It effectively inhibits LPS-induced neutrophilia, making it a valuable tool for research in inflammation and immunology, particularly in studies related to allergic asthma. AIM-102 facilitates a deeper understanding of immune mechanisms and the modulation of inflammatory processes in various disease contexts. -
Non-Steroidal Anti-Inflammatory Drug
Bumadizone calcium is the calcium salt form of Bumadizone, functioning as a non-steroidal anti-inflammatory drug (NSAID). It has demonstrated efficacy in alleviating symptoms associated with chronic inflammatory diseases. However, it is important to note that Bumadizone calcium can be irritating to the gastric lining, potentially resulting in gastric bleeding and ulceration. This compound is primarily utilized in research investigating anti-inflammatory pathways and associated gastrointestinal effects. -
Anti-inflammatory Agent
Anti-inflammatory Agent 82 is designed to inhibit inflammatory pathways, providing potential analgesic effects. Its mechanism of action may involve the modulation of pro-inflammatory cytokines, thus reducing inflammation in various tissues. This reagent is suitable for research applications focused on pain management and inflammatory disease models. -
Anti-inflammatory Agent
Fanetizole mesylate is an anti-inflammatory agent that targets pro-inflammatory pathways to mitigate inflammation. It demonstrates significant biological activity in reducing inflammation and can be utilized in research focused on various inflammatory diseases. This compound is instrumental for studies investigating therapeutic interventions in inflammatory conditions. -
Anti-inflammatory Agent
Neuroprotective Agent 4 is a novel small molecule that functions primarily as an antioxidant and anti-inflammatory agent. It exhibits significant neuroprotective effects, making it a valuable tool in the study of ischemic stroke and associated neurodegenerative diseases. This compound is instrumental in exploring therapeutic strategies for conditions characterized by oxidative stress and inflammation in neural tissues. -
Antiinflammatory Agent
K 308 is a non-steroidal anti-inflammatory agent that inhibits the production of pro-inflammatory cytokines. It demonstrates significant biological activity in reducing inflammation and providing symptomatic relief in various inflammatory conditions. This compound is valuable for research applications focused on understanding inflammatory pathways and developing novel therapeutic strategies for chronic diseases. -
Anti-inflammatory Agent
Flavanone hydrazone is a potent non-steroidal anti-inflammatory agent that primarily targets inflammatory pathways. It effectively inhibits ocular inflammation induced by lens proteins, making it a valuable compound for research related to eye health and inflammatory responses. This compound can be utilized in studies exploring the mechanisms of inflammation and potential therapeutic applications in ocular diseases. -
Anti-inflammatory Agent
Butetamate (HH105) is an anti-inflammatory agent primarily targeting inflammatory pathways. This compound demonstrates potential efficacy in alleviating symptoms associated with respiratory system conditions. It can be utilized to formulate thin films for research applications focused on inflammation and respiratory health. -
Anti-inflammatory Agent
Flufenamate aluminum is a non-steroidal anti-inflammatory agent that inhibits cyclooxygenase (COX) enzymes, leading to a reduction in prostaglandin synthesis. It exhibits significant anti-inflammatory activity and is utilized in research related to pain management and inflammatory processes. This compound is valuable for studying various inflammatory diseases and potential therapeutic interventions. -
Anti-inflammatory Agent
Malkangunin, an anti-inflammatory agent derived from red ginseng, exhibits significant biological activity in modulating inflammatory processes. Its potential applications in medical research include addressing conditions such as premature ovarian failure, making it a valuable compound for studies focused on reproductive health and inflammation-related disorders. -
Anti-inflammatory Agent
Anti-inflammatory agent 34 (Compound IVf) is an orally bioavailable anti-inflammatory reagent that functions by inhibiting key inflammatory pathways. This compound exhibits significant analgesic properties and is useful in research focused on pain management and inflammation-related disorders. Its application extends to studies investigating the molecular mechanisms of inflammation and the development of therapeutic strategies for inflammatory diseases. -
Anti-inflammatory Agent
4-Hydroxy-2,3-dimethoxyxanthone is an anti-inflammatory agent derived from Hypericum oblongifolium. This compound exhibits significant inhibition of inflammatory pathways, making it valuable in research focused on chronic inflammation and related diseases. Its potential applications include studying mechanisms of inflammation and developing novel therapeutic strategies in inflammatory disorders. -
Anti-Inflammatory Agent
Polyporoid B is an ergostane-type ecdysteroid that serves as a potent anti-inflammatory agent. It demonstrates significant anti-inflammatory activity in vivo, making it a valuable tool for research in inflammation-related studies and therapeutic development. Its unique mechanism of action may provide insights into new treatments for inflammatory diseases. -
Nonsteroidal Antiinflammatory Agent
IDPH-8261 is an orally active nonsteroidal anti-inflammatory agent that targets cyclooxygenase enzymes to inhibit prostaglandin synthesis. Its key biological activity includes reducing inflammation and alleviating pain associated with various inflammatory conditions. This compound is applicable in research focused on inflammatory diseases, including arthritis, and may facilitate the investigation of therapeutic strategies for managing chronic inflammation.
