Catalog No.
Product Name
Application
Product Information
Citations
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Anti-inflammatory Agent
Lonchocarpic acid acts as an anti-inflammatory agent, targeting pathways involved in neuroinflammation. It has demonstrated efficacy in models of LPS- or poly(I:C)-induced neuroinflammation, suggesting potential applications in investigating neuroinflammatory conditions. This compound is useful for researchers exploring the molecular mechanisms of inflammation and developing therapeutic strategies for related disorders. -
Anti-inflammatory Agent
Ibuproxam is a non-steroidal anti-inflammatory agent that exhibits potent inhibition of cyclooxygenase enzymes, thus reducing the synthesis of prostaglandins. This compound is utilized in various studies focused on pain relief and inflammation reduction, making it relevant for pharmacological research and therapeutic applications. Its mechanisms may contribute to further understanding of inflammatory pathways and potential drug development. -
Anti-inflammatory Agent
Isoxepac is an orally active non-steroidal anti-inflammatory agent that primarily targets inflammation pathways. It effectively inhibits carrageenan-induced paw edema and adjuvant-induced polyarthritis, alongside reducing prostaglandin synthesis. Isoxepac has demonstrated analgesic effects in postoperative pain management with minimal side effects. This compound is valuable for research involving inflammatory conditions, such as rheumatoid arthritis, and pain management studies. -
Anti-inflammatory Agent
Anti-inflammatory agent 106 is a derivative of Paeonol that functions as a potent anti-inflammatory agent. It demonstrates significant efficacy in inhibiting xylene-induced ear swelling in murine models, making it valuable for the study of inflammatory responses. This compound can be utilized in research focused on inflammatory diseases such as rheumatoid arthritis, psoriasis, and type 1 diabetes. -
Anti-inflammatory Agent
Betamethasone-17-butyrate-21-propionate is a potent anti-inflammatory agent primarily used in the treatment of inflammatory skin conditions. This synthetic corticosteroid acts by inhibiting the release of inflammatory mediators, thereby reducing erythema, swelling, and discomfort. Its efficacy makes it a valuable research tool for studying corticosteroid effects on skin inflammation and for evaluating therapeutic strategies in dermatological applications. -
Anti-inflammatory Agent
Bucloxic acid calcium is an anti-inflammatory agent classified as a pyrrazole derivative. It exhibits potent anti-inflammatory properties, making it suitable for research applications in chronic glomerular nephropathies. This compound can aid in the study of inflammatory processes and potential therapeutic interventions in kidney diseases. -
Anti-Inflammatory Agent
SM-8849 is a thiazole derivative characterized by its anti-inflammatory properties. This compound selectively targets and inactivates T cells associated with delayed-type hypersensitivity (DTH) reactions, effectively disrupting the key immunopathological processes implicated in arthritis while sparing humoral immune functions such as antibody synthesis. In a Type II Collagen-induced mouse model of arthritis, SM-8849 demonstrated significant efficacy by relieving clinical symptoms and mitigating bone destruction and joint damage. SM-8849 serves as a valuable reagent for research on autoimmune diseases, particularly rheumatoid arthritis. -
Anti-inflammatory Agent
HMR-4011A is a chemically modified derivative of Contignasterol, functioning as an orally active anti-inflammatory agent. It exhibits significant efficacy in reducing inflammation and has potential applications in respiratory research, particularly in the context of asthma. HMR-4011A offers valuable insights for studies focused on inflammatory pathways and therapeutic interventions. -
Anti-Inflammatory Agent
Mofebutazone is a monophenyl analogue of Phenylbutazone, functioning primarily as an anti-inflammatory agent. It exhibits potent anti-inflammatory activity and is utilized in research related to asthma and other inflammatory conditions. Its oral bioavailability makes it a valuable tool for studying the therapeutic effects of anti-inflammatory compounds in various biological models. -
Anti-inflammatory Agent
Stemospironine is an alkaloid derived from plants of the genus Hyacinth, functioning primarily as an anti-inflammatory agent. It exhibits significant biological activity as a cough suppressant while also serving as a valuable tool for investigating various inflammatory conditions. Its potential applications in research include exploring mechanisms of inflammation and evaluating therapeutic strategies for related diseases. -
Anti-inflammatory agent
SerBut is a serine-conjugated butyrate prodrug designed to exert anti-inflammatory effects. It demonstrates potential therapeutic activity in modulating inflammation, making it suitable for research applications targeting inflammatory pathways and related diseases. Its oral bioactivity enhances its utility in in vivo studies. -
Nonsteroidal Anti-inflammatory Drug
Azapropazone is a nonsteroidal anti-inflammatory drug (NSAID) primarily targeting the inhibition of cyclooxygenase enzymes. This compound exhibits significant anti-inflammatory and analgesic properties, making it valuable in the study of rheumatoid arthritis and related inflammatory disorders. Researchers can utilize Azapropazone to investigate its effects on pain management and the underlying mechanisms of inflammatory conditions. -
Anti-inflammatory Agent
Fenclozic acid is an orally active anti-inflammatory agent that exerts its effects by inhibiting prostaglandin synthesis. It demonstrates significant analgesic and antipyretic properties, making it useful in the study of pain and fever management. Researchers commonly utilize fenclozic acid to explore pathways underlying inflammation and to develop therapeutic strategies for related conditions. -
Anti-inflammatory Substance
Kebuzone is a non-steroidal anti-inflammatory compound that targets inflammatory pathways. It exhibits significant anti-inflammatory activity and may be useful in research related to inflammatory diseases, including thrombophlebitis and rheumatoid arthritis. This reagent provides a valuable tool for studying mechanisms of inflammation and exploring potential therapeutic strategies. -
Non-steroidal Anti-inflammatory Agent
Difenpiramide is a non-steroidal anti-inflammatory agent that exhibits pronounced anti-inflammatory, analgesic, antipyretic, and uricosuric properties. This compound also demonstrates platelet anti-aggregation activity, making it valuable for research applications in inflammation, pain management, and cardiovascular studies. Its multifaceted biological activities contribute to its potential use in various therapeutic contexts. -
Anti-inflammatory Agent
Furobufen is an anti-inflammatory agent that exerts antiarthritic and antipyretic effects, providing significant relief in conditions characterized by inflammation. Its analgesic properties are particularly pronounced in inflamed tissues, making it a valuable compound for research applications focused on pain management and inflammatory diseases. This compound can be utilized in exploring therapeutic strategies for various inflammatory conditions. -
Antiinflammatory Agent
D228 is an orally active anti-inflammatory agent that targets T and B lymphocytes. It effectively reduces ConA-induced T cell proliferation with an IC50 of 42.85 μM and LPS-induced B cell proliferation with an IC50 of 3.15 μM. D228 demonstrates efficacy in the treatment of inflammatory bowel disease (IBD) by alleviating inflammation in the DSS-induced IBD model, primarily through the downregulation of the MyD88/TRAF6/p38 signaling pathway. -
Anti-Inflammatory Agent
Anti-inflammatory agent 32 (compound C3) functions as an anti-inflammatory agent, exhibiting notable antioxidative properties. This compound is ideal for research focused on anti-inflammatory mechanisms and skin care product development, contributing valuable insights into inflammatory pathways and therapeutic interventions. -
Anti-inflammatory Agent
Nicotredole is an orally active anti-inflammatory agent that primarily targets inflammatory pathways. It demonstrates significant anti-inflammatory and analgesic effects, exhibiting potency comparable to that of Phenylbutazone while presenting only minimal ulcerogenic activity. Nicotredole is suitable for research applications focused on inflammation and pain management studies. -
Anti-inflammatory Agent
Tetridamine is a non-steroidal anti-inflammatory agent that primarily targets inflammatory pathways. It has been demonstrated to significantly reduce paw swelling and alleviate pain sensitivity in various models of inflammation. This compound is valuable for research into inflammation-related conditions and the development of novel anti-inflammatory therapies. -
Anti-inflammatory Agent
Cedrol methyl ether is an anti-inflammatory agent derived from ginger. It exhibits significant anti-inflammatory activity, making it a valuable compound for research applications related to hyperhidrosis and abnormal vaginal discharge. Its potential uses in studying inflammatory conditions highlight its importance in biochemical and therapeutic investigations. -
Anti-Inflammatory Agent
Mosedipimod is a monoacetyldiaglyceride that functions as a Toll-Like Receptor (TLR) signaling inhibitor. It exhibits significant anti-inflammatory activity by reducing myeloperoxidase expression in lung tissue, thereby attenuating airway inflammation. This compound is primarily utilized in research related to chronic obstructive pulmonary disease (COPD), contributing to the understanding of inflammatory pathways and potential therapeutic interventions. -
Anti-inflammatory Analgesic
Isamfazone is an anti-inflammatory analgesic that acts primarily by inhibiting the production of pro-inflammatory mediators. It exhibits significant efficacy in reducing pain and inflammation, making it valuable for investigations into pain management and inflammatory diseases. This compound is utilized in preclinical studies to explore its therapeutic potential in various conditions associated with inflammation. -
Anti-inflammatory Drug
Rivasterat is a cholesterol-derived steroid that exhibits potent anti-inflammatory activity. It functions by modulating inflammatory pathways, making it a valuable tool in research focused on inflammation-related diseases. Its potential applications include studying the role of inflammation in chronic conditions and evaluating therapeutic strategies for inflammatory disorders. -
Anti-inflammatory Agent
Epmedin C is an orally active anti-inflammatory agent and immunomodulator that targets multiple key proteins, including UCP1, Caspase-1, CDK2, and Keap1. This compound effectively inhibits epithelial cell proliferation by disrupting the CDK2/Cyclin E complex, while also upregulating Nrf2 expression, reducing reactive oxygen species levels, and inhibiting the secretion of pro-inflammatory cytokines. Through these mechanisms, Epmedin C aids in restoring antibody production and alleviating tissue damage, making it relevant for research on conditions such as obesity, immunotoxicity induced by Deoxynivalenol, and mammary hyperplasia. -
Anti-inflammatory Agent
Saikosaponin A is an anti-inflammatory agent primarily derived from Bupleurum chinense. It effectively regulates lipid metabolism and promotes cholesterol efflux, making it relevant in early atherosclerosis research. Furthermore, Saikosaponin A acts as a potential agonist of peroxisome proliferator-activated receptor γ (PPAR-γ), significantly enhancing its expression. This compound is particularly useful in studies related to hyperlipidemic pancreatitis. -
Anti-inflammatory Agent
Physalin L is an anti-inflammatory agent that inhibits lipopolysaccharide (LPS)-induced nitric oxide (NO) production in macrophages, achieving an average inhibitory rate of 70.97%. This compound is valuable for research focused on inflammation pathways and can be utilized to investigate its potential therapeutic effects in various inflammatory conditions. -
Anti-inflammatory Agent
Chikusetsusaponin IVa is an orally active anti-inflammatory agent that targets YAP, demonstrating a binding affinity with a KD value of 0.388 mM. This compound effectively reduces the expression of inflammatory mediators such as IL-6, IL-10, and COX-2, while modulating nitric oxide production and promoting reactive oxygen species generation. Additionally, Chikusetsusaponin IVa induces apoptosis, inhibits MAPK and TAZ signaling pathways, and regulates Nrf2 and JAK/STAT pathways. It exhibits potential as an anti-H9N2 avian influenza virus agent and demonstrates anti-cancer properties, along with hepatoprotective and osteoprotective effects, making it a valuable tool for research in inflammation and cancer biology. -
Anti-inflammatory Agent
Praeruptorin A is an anti-inflammatory compound derived from Peucedanum praeruptorum. It demonstrates significant anti-inflammatory activity by inhibiting NF-κB activation, which is crucial for mediating inflammatory responses. This compound is valuable in research applications focused on inflammation-related signaling pathways and the development of anti-inflammatory therapies. -
Antiinflammatory Agent
Sodium gualenate is a hydrophilic derivative of guaiazulene that functions as an anti-inflammatory agent. It exhibits significant anti-inflammatory and wound-healing properties, making it useful in the treatment of conditions such as duodenal ulcers, gastric ulcers, and gastritis. This compound is valuable for research focused on gastrointestinal health and the modulation of inflammatory responses. -
Anti-inflammatory Compound
Methyl 2-acetoxybenzoate, also known as methyl acetylsalicylate, serves as a prodrug that exerts anti-inflammatory effects. Upon chemical or enzymatic hydrolysis, it converts to methyl 2-hydroxybenzoate, which is known for its analgesic properties. This compound is applicable in research pertaining to inflammatory diseases and can be utilized as an analgesic agent in topical formulations such as liniments. -
Anti-inflammatory Agent
6α-Fluoroprednisolone is an anti-inflammatory agent that serves as an internal standard for the analysis of methylprednisolone, prednisolone, and prednisone. This compound is essential for research applications related to congenital adrenal virilism and Addison's disease, aiding in the understanding of adrenal function and corticosteroid therapy. It is an invaluable tool for studies focused on steroid hormone action and metabolic regulation. -
Anti-Inflammatory Corticosteroid
Paramethasone is an anti-inflammatory corticosteroid that targets glucocorticoid receptors. It is known for its ability to reduce inflammation and modulate immune responses, making it valuable in the treatment of various inflammatory and autoimmune conditions. This compound is commonly utilized in research to investigate corticosteroid mechanisms and therapeutic applications in disorders such as asthma, arthritis, and other inflammatory diseases. -
Anti-inflammatory and Protein-Binding Inhibitor
4-Acetylaminoantipyrine is a derivative of antipyrine that functions primarily as an anti-inflammatory agent and a protein-binding inhibitor. It acts as a PGE2-dependent blocker and inhibits cyclooxygenase (COX), thereby modulating inflammatory pathways. Additionally, 4-acetylaminoantipyrine has the capability to inhibit Cu/Zn superoxide dismutase (Cu/ZnSOD) and can spontaneously bind with bovine serum albumin (BSA), resulting in conformational changes. This compound is valuable for research applications in inflammation and protein interaction studies. -
Pro-inflammatory Mediator Inhibitor
Heparin disaccharide III-S (trisodium) is a heparin-derived disaccharide that serves as a pro-inflammatory mediator inhibitor. It effectively inhibits the spontaneous secretion of interleukin-8 (IL-8) and interleukin-1 beta (IL-1β) in intestinal epithelial cells by acting at the post-translational level without affecting mRNA or intracellular mediator concentrations. This compound is useful for research on inflammatory responses and the regulation of cytokine secretion in intestinal models. -
Pro-inflammatory Mediator Inhibitor
Heparin disaccharide I-H (trisodium) is a heparin-derived disaccharide that acts as a pro-inflammatory mediator inhibitor. This compound effectively blocks the spontaneous secretion of IL-8 and IL-1β in intestinal epithelial cells at the post-translational level, while leaving mRNA expression levels and intracellular contents unaffected. Demonstrating dose-dependent anti-inflammatory activity, Heparin disaccharide I-H (trisodium) is valuable for research applications targeting intestinal inflammation and associated signaling pathways. -
Anti-inflammatory/Analgesic Agent
Nitraquazone is an anti-inflammatory and analgesic agent that inhibits phosphodiesterase, leading to increased intracellular levels of cyclic adenosine monophosphate (cAMP). This mechanism underlies its potential use in research focused on inflammation and pain management. Nitraquazone serves as a valuable tool in the investigation of anti-inflammatory pathways and analgesic effects in various biological contexts. -
Anti-inflammatory/tumor Agent
Hesperetin triacetate is a compound known for its anti-inflammatory and anti-tumor properties. It exerts its effects by inhibiting the denaturation of bovine serum albumin in vitro and reducing carrageenan-induced paw swelling in mouse models in vivo. Additionally, Hesperetin triacetate demonstrates anti-proliferative activity against breast cancer cells, inducing DNA degradation and apoptosis. This compound is suitable for research focused on breast cancer and inflammation mechanisms. -
Anti-inflammatory agent
Sanggenon B is an anti-inflammatory agent that exhibits inhibitory effects on nitric oxide (NO) production in LPS-stimulated RAW264.7 macrophage cells. This compound, extracted from mulberry trees, serves as a valuable tool in research applications focused on understanding and mitigating inflammatory processes. Its biological activity positions it as a potential candidate for further exploration in therapeutic contexts related to inflammation. -
Anti-Inflammatory Agent
Cucurbitadienol is a natural compound primarily known for its anti-inflammatory properties. Isolated from the seeds of Trichosanthes kirilowii, this tetracyclic terpene has been shown to modulate inflammatory pathways. Its biological activity makes it a valuable tool in research focused on understanding and developing treatments for inflammatory diseases. -
Anti-inflammatory Agent
Alpinenone is a sesquiterpene compound with anti-inflammatory properties. It acts by inhibiting the overproduction of nitric oxide (NO), thereby reducing inflammation. Alpinenone is suitable for research applications focused on inflammation-related diseases, as well as gastrointestinal and urinary system disorders. -
Anti-Inflammatory Agent
Prinomide triethanolamine is an orally available nonsteroidal anti-inflammatory agent targeting pathways involved in inflammation. It exhibits significant anti-inflammatory properties and is utilized in research focused on inflammatory diseases, including rheumatoid arthritis. This reagent provides valuable insights into the mechanisms of inflammation and the potential therapeutic effects of anti-inflammatory compounds. -
Anti-Inflammatory Agent
Anti-inflammatory agent 36 is a potent anti-inflammatory compound that selectively inhibits lipopolysaccharide (LPS)-induced macrophage activation. This mechanism aids in modulating inflammatory responses, making it a valuable tool for studying inflammatory pathways and potential therapeutic interventions. Its application is pivotal in researching conditions characterized by excessive inflammation, contributing to a better understanding of inflammatory diseases. -
Anti-inflammatory Agent
EVT‑401 is an anti-inflammatory agent that modulates immune responses by inhibiting key inflammatory pathways. It demonstrates significant pharmacological effects in vivo and is valuable for studying various inflammatory conditions. EVT‑401 is a potent tool for research focused on understanding the mechanisms of inflammation and potential therapeutic interventions. -
Anti-inflammatory/antioxidant
S-Carboxymethyl-L-cysteine L-lysine monohydrate is a mucosal active compound that demonstrates notable anti-inflammatory and antioxidant properties. This reagent is primarily utilized in research related to chronic obstructive pulmonary disease (COPD), where it may help in elucidating the underlying mechanisms of inflammation and oxidative stress. Its unique profile makes it valuable for studies aimed at developing therapeutic strategies for respiratory conditions. -
Anti-inflammatory Agent
Zidometacin is a nonsteroidal anti-inflammatory agent that primarily targets prostaglandin synthesis, effectively reducing inflammation with a diminished risk of gastrointestinal toxicity. It exhibits notable antinociceptive and antipyretic properties, demonstrating low ulcerogenic potential in rat models. Zidometacin is applicable in research focused on analgesia and osteoarthritis, contributing valuable insights into pain management and inflammatory processes. -
Anti-inflammatory Agent
PH-46A is an indane dimer that operates as an anti-inflammatory agent. It has demonstrated the ability to reduce histological damage and lower serum amyloid A (SAA) levels in murine models of colitis. This compound is valuable for research applications focused on inflammatory diseases and therapeutic intervention strategies. -
Anti-inflammatory Agent
5,7,5′-Trihydroxy-3′,4′-dimethoxyflavonol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside functions as an anti-inflammatory agent and belongs to the flavonol glycoside class. This compound, isolated from Ginkgo biloba leaves, demonstrates significant antioxidative and cardioprotective properties. Its application extends to investigating mechanisms underlying inflammation and cardiac injury, making it a valuable reagent for biochemical and pharmacological research. -
Anti-inflammatory Agent
Chinoin 127 is a non-anesthetic analgesic agent that exhibits significant anti-inflammatory properties. Demonstrated to provide potent analgesic effects in various models, including the hot plate test, Randall-Selitto test, and torsion test, Chinoin 127 is valuable for research applications aimed at understanding pain mechanisms and developing therapies for inflammatory conditions. -
Anti-inflammatory Agent
Diacetyl boldine is an anti-inflammatory agent known for its soothing and moisturizing properties. This compound is investigated for its potential effects on skin disorders, particularly melasma and lentigo senilis. Its biological activity makes it a valuable reagent for research focused on dermatological applications and skin health.
