Mps1

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  1. Mps1 inhibitor

    AZ 3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). It interferes with chromosome alignment and overrides spindle assembly checkpoint and also Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores.

  2. Mps1 inhibitor

    Mps1-IN-1 is a highly potent and selectibe Mpsl inhibitor with IC50 of 367 nM; >1000-fold selectivity relative to the 352 member kinase panel with the major exceptions of Alk and Ltk.
  3. Mps1 inhibitor

    MPI-0479605 is an ATP competitive and selective inhibitor of mitotic kinase Mps1

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