MMP

Cat. No.

A12826

CAS No.

154039-60-8

Marimastat

Marimastat acted as a broad-spectrum matrix metalloproteinase inhibitor.

Cat. No.

A12985

CAS No.

130370-60-4

Batimastat (BB-94)

Synonyms: BB 94

Batimastat (BB-94) is a potent and synthetic inhibitor of a broad spectrum of matrix metalloproteinases (MMPs), including interstitial collagenase (IC50 = 3 nM), stromelysin (IC50 = 20 nM), Mr 72,000 type IV collagenase (IC50 = 4 nM), Mr 92,000 type IV collagenase (IC50 = 4 nM), and matrilysin (IC50 = 6 nM). It is a low-molecular-weight (MW = 478) and peptide-like collagen substrate analogue consisting of a peptide backbone and a hydroxamic acid group which bind to MMPs and the catalytically active zinc atom respectively.

Cat. No.

A13072

CAS No.

7497-07-6

NSC 405020

NSC-405020 is a membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L).

Cat. No.

A15292

CAS No.

704888-90-4

ARP 100

ARP 100 is a selective inhibitor of matrix metalloproteinases 2 (MMP-2) with IC50 value of 12 nM.

Cat. No.

A11345

CAS No.

193022-04-7

CTS-1027

Synonyms: RS 130830; Ro 1130830

CTS-1027 is a potent MMP inhibitor that protects Against TNFα- and α-Fas-Induced liver Injury.

Cat. No.

A12848

CAS No.

101342-45-4

4-epi-Chlortetracycline Hydrochloride

Synonyms: ECTC

4-epi-Chlortetracycline Hydrochloride is a tetracycline derivative that acts as a metalloproteinase (MMP) inhibitor, used in treating tissue destructive diseases and cancer

Cat. No.

A12853

CAS No.

869296-13-9

T-26c

T-26c is highly potent and selective matrix metalloproteinase-13 (MMP-13) inhibitor with an IC50 of 6.75 pM and more than 2600-fold selectivity over the other related metalloenzymes.

Cat. No.

A13185

CAS No.

312930-75-9

MMP3 inhibitor 1

MMP3 inhibitor 1 is a potent and highly selective MMP-3 inhibitor with an IC50 of 1 nM.

Cat. No.

A13320

CAS No.

142880-36-2

GM 6001

Synonyms: Galardin; Ilomastat

GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs).

Cat. No.

A13330

CAS No.

287405-51-0

Apratastat

Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) .

Cat. No.

A13597

CAS No.

307002-71-7

CL-82198

Synonyms: MMP-13 inhibitor

CL-82198 is a selective inhibitor of human collagenase-3, also known as matrix metalloproteinase-13 (MMP-13), producing 89% inhibition at 10 mg/ml.

Cat. No.

A13724

CAS No.

143457-40-3

(S,S)-TAPI-0

Synonyms: TNF Protease Inhibitor 0

(S,S)-TAPI-0 is an inhibitor of TACE (IC50 = 50-100 nM) as well as other matrix and membrane metalloproteases

Cat. No.

A14009

CAS No.

187034-31-7

TAPI-2

Synonyms: TNF Protease Inhibitor 2

TAPI-2 is an inhibitor of TACE, ADAMs, ACE secretase, and other MMPs (metalloproteinases). TAPI-2 blocks release of DCC7, APP, TNFα, L-selectin, NOTCH, TGFα, IL-6R9, erbB2/HER2, and ACE. This inhibitor has been used in tissue culture.

Cat. No.

A14070

CAS No.

171235-71-5

(S,S)-TAPI-1

Synonyms: TAPI1

TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.

Cat. No.

A14243

CAS No.

164204-38-0

Phosphoramidon Disodium Salt

Phosphoramidon Disodium Salt is a metalloendopeptidase inhibitor.

Cat. No.

A14253

CAS No.

292605-14-2

SB-3CT

SB-3CT is an effective and selective gelatinase inhibitor with Ki of 13.9 nM and 600 nM for MMP-2 and MMP-9.

Cat. No.

A15293

CAS No.

849773-63-3

ARP 101

ARP 101, selective inhibitor of MMP-2 that displays ~ 600-fold selectivity over MMP-1 (IC50 values are 0.81 and 486 nM respectively).

Cat. No.

A15297

CAS No.

210755-45-6

CP 471474

CP 471474, broad spectrum MMP inhibitor (IC50 values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively).

Cat. No.

A15305

CAS No.

223472-31-9

ONO 4817

Synonyms: MMP Inhibitor V

ONO 4817 is used for testing effective treatment of MMP-related diseases.

Cat. No.

A15307

CAS No.

199850-67-4

PD 166793

PD166793 is a cell-permeable compound that strongly inhibits MMP (matrix metalloproteinase) -2 , -3, and -13, and weakly inhibits AMP deaminase, MMP-1, -7, -9, and -14.

Cat. No.

A15311

CAS No.

190648-49-8

Cipemastat (Ro 32-3555)

Synonyms: Ro 32-3555

Ro 32-3555 is a potent, collagenase-selective MMP inhibitor .

Cat. No.

A15316

CAS No.

230961-21-4

UK 370106

UK 370106 is a highly selective MMP-3 and MMP-12 inhibitor .

Cat. No.

A15317

CAS No.

307002-73-9

WAY 170523

WAY 170523 has been reported to be a selective and potent inhibitor of MMP-13.

Cat. No.

A15323

CAS No.

230961-08-7

UK 356618

UK 356618 is a selective and potent inhibitor of MMP-3 that shows selectivity over a range of MMPs.

Cat. No.

A15326

CAS No.

130464-84-5

Batimastat sodium salt

Synonyms: BB-94 sodium salt

Batimastat is an anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. Batimastat (BB-94) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor.