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Catalog No.
Product Name
Application
Product Information
Citations
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Bacterial Inhibitor
Triclosan-methyl is a transformation product of triclosan, functioning primarily as a bacterial inhibitor. It exhibits significant antimicrobial activity, making it relevant for applications in assessing bacterial resistance and efficacy of antimicrobial compounds. This compound is commonly utilized in research related to personal care products and their environmental impact, particularly in evaluating the persistence and degradation of antibacterial agents. -
Bacterial Inhibitor
(+)-Viroallosecurinine is a potent antibacterial alkaloid that acts as a bacterial inhibitor. It demonstrates significant antimicrobial activity, with a minimum inhibitory concentration (MIC) of 0.48 μg/mL against Pseudomonas aeruginosa and Staphylococcus aureus. This compound is suitable for research applications focused on understanding bacterial resistance and developing novel antibacterial agents. -
Bacterial Inhibitor
Ribocil-C (R enantiomer) is a selective inhibitor targeting bacterial riboflavin riboswitches. This compound disrupts riboflavin biosynthesis by binding to specific RNA structures, effectively inhibiting bacterial growth. It is useful in research applications focusing on bacterial gene regulation and the development of novel antimicrobial strategies. -
Bacterial Inhibitor
Chloroneb is a bacterial inhibitor with fungicidal properties that effectively protects plants. It is utilized in analytical applications for the detection of organochlorine pesticide residues, demonstrating excellent selectivity, stability, and reproducibility. Chloroneb has been successfully applied in the analysis of various samples, including licorice, cucumber, river water, and soil, providing reliable results for environmental monitoring and agricultural research. -
Bacterial Inhibitor
Amifloxacin is a synthetic antibacterial agent belonging to the quinolone class, primarily targeting bacterial DNA gyrase and topoisomerase IV. This compound exhibits potent bactericidal activity against a broad spectrum of gram-negative and gram-positive bacteria. It is commonly utilized in research applications for studying bacterial infections and evaluating the efficacy of antibiotic treatments. -
Bacterial Inhibitor
Lavendamycin is a quinolinedione with antimicrobial properties, primarily acting as a bacterial inhibitor. It demonstrates significant antibacterial and antitumor activity, making it a valuable compound for research in microbiology and cancer biology. Its unique mechanism and efficacy position Lavendamycin as a potential tool for exploring therapeutic approaches against bacterial infections and tumors. -
Bacterial Inhibitor
Dodine is a bacterial inhibitor with fungicidal properties, primarily targeting various plant pathogens. It is effective in controlling diseases such as black spot in apples, pears, and pecans, as well as brown rot in peaches, along with a range of foliar diseases affecting strawberries, cherries, jacaranda, and black walnuts. In addition to its agricultural applications, Dodine serves as an industrial biocide and preservative, making it valuable in diverse research settings focused on plant disease management and microbial control. -
Bacterial Inhibitor
Meso-2,6-Diaminopimelic acid serves as a critical biosynthetic precursor in the synthesis of the essential amino acid L-lysine. It plays a vital role in the formation of peptidoglycan, a key structural component of the cell walls in various bacterial species. This compound is primarily utilized in research related to bacterial inhibition and the study of cell wall biosynthesis, making it essential for antimicrobial investigations and the development of antibacterial agents. -
Bacterial Inhibitor
D-Homoserine lactone is a bacterial inhibitor that functions as a signaling molecule regulating quorum sensing through its interaction with acyl-homoserine lactone (AHL) synthase RhlI. By inhibiting RhlI activity, D-Homoserine lactone disrupts bacterial communication, making it a valuable tool in studies of bacterial behavior and pathogenicity. Additionally, as an enantiomer of L-homoserine lactone, it serves as an inhibitor of serine hydroxymethyltransferase, expanding its potential applications in biochemical research and synthetic biology. -
Bacterial Inhibitor
Afabicin disodium is a specialized bacterial inhibitor that functions as a proagent for Debio1452. It specifically targets Staphylococcus species while exhibiting minimal activity against other Gram-positive and Gram-negative bacteria. The active form, Debio1452, is an inhibitor of FabI, an enzyme essential for fatty acid biosynthesis in staphylococci, making it a valuable tool for research in combating staphylococcal infections. -
Bacterial Inhibitor
Epinecidin-1 is a potent antimicrobial peptide derived from the orange-spotted grouper (Epinephelus coioides), targeting various bacterial strains. It exhibits substantial antibacterial, antifungal, antiviral, and antiprotozoal activity, making it a valuable tool in studies examining microbial inhibition. Additionally, its immunomodulatory and wound healing properties further support research applications in infection control and regenerative medicine. -
Bacterial Inhibitor
Tuberculosis Inhibitor 3 (Compound 2i) is a potent antibacterial agent targeting Mycobacterium tuberculosis, demonstrating a minimum inhibitory concentration (MIC) of less than 0.016 μg/mL against both sensitive and resistant strains. This compound exhibits favorable pharmacokinetic properties, including adequate oral bioavailability, making it a promising candidate for further research and development in tuberculosis treatment strategies. -
Bacterial Translation Inhibitor
NOSO-502 is a bacterial translation inhibitor that targets ribosomal activity in Enterobacteriaceae. It demonstrates potent antibacterial properties while maintaining a favorable safety profile. This compound is suitable for research applications focused on bacterial protein synthesis and the development of novel antimicrobial agents. -
Bacterial Inhibitor
Antitubercular agent-10 is a bacterial inhibitor that demonstrates potent antitubercular activity, exhibiting a minimum inhibitory concentration (MIC) of 30 nM. This compound is primarily utilized in research focused on combating tuberculosis, enabling investigations into its mechanisms of action and potential therapeutic strategies. Its effectiveness makes it a valuable tool for studying mycobacterial infections and the development of novel antitubercular therapies. -
Bacterial Inhibitor
CGI-17341 is a 5-nitroimidazole antibacterial agent targeting bacterial pathogens, specifically Mycobacterium tuberculosis. This compound demonstrates significant inhibitory activity against both sensitive and multidrug-resistant strains of M. tuberculosis in vitro. In vivo studies indicate that CGI-17341 can prolong the survival time of infected mice in a dose-dependent manner, making it a valuable tool for research on tuberculosis and related bacterial infections. -
Bacterial Inhibitor
Cephabacin M4 is a cephalosporin derivative, specifically a 7-methoxydesacetylcephalosporin, that functions as a bacterial inhibitor. It exhibits significant antimicrobial activity against a range of bacterial pathogens, making it valuable for research involving antibiotic development and bacterial resistance studies. Isolated from the culture filtrate of Xanthomonas lactamica, Cephabacin M4 serves as a useful tool in exploring cephalosporin efficacy and mechanisms of action. -
Bacterial Inhibitor
Antibacterial agent 202 (compound 45c) is a bacterial inhibitor that targets Gram-negative bacteria, demonstrating significant antibacterial activity against strains such as Escherichia coli, Klebsiella pneumoniae, and especially Pseudomonas aeruginosa, with a minimum inhibitory concentration (MIC) ranging from 7.8 to 31.25 μM. This compound functions by disrupting the integrity of bacterial cell membranes, making it a valuable tool for research into bacterial infections and potential therapeutic applications. -
Bacterial Inhibitor
BPH-651 is a bacterial inhibitor that targets dehydrosqualene synthase, an essential enzyme involved in bacterial terpenoid biosynthesis. This compound exhibits potent antibacterial activity by binding to multiple sites on the enzyme, revealing structural insights into the mechanism of action and inhibition of head-to-head prenyltransferase. BPH-651 is useful for research focused on designing new antibacterial agents and studying bacterial resistance mechanisms. -
Bacterial Inhibitor
Antistaphylococcal agent 1 functions as a bacterial inhibitor, specifically targeting Staphylococcus species. This compound exhibits significant antimicrobial activity, making it a valuable tool in the study of bacterial infections and resistance mechanisms. Its application can aid in the development of novel therapeutic strategies against staphylococcal infections. -
Bacterial Inhibitor
(Rac)-DNDI-8219 is a bacterial inhibitor with demonstrated efficacy against Leishmania species. This compound exhibits potent antituberculosis and anti-leishmanial activities, showcasing significant effectiveness in both the Leishmania donovani mouse model and the Leishmania infantum hamster model. Interestingly, the R-6 candidate form of (Rac)-DNDI-8219 offers excellent oral bioavailability and efficacy in the hamster model, making it a valuable tool for research focused on treating leishmaniasis and tuberculosis. -
Bacterial Inhibitor
Acaterin is a bacterial inhibitor derived from Pseudomonas, known for its role in antimicrobial activity. Research indicates that its biosynthesis is regulated through a complex gene cluster, with studies highlighting its associated biosynthetic pathway. Comparative transcriptomics further demonstrates the compound's formation is intricately linked to bacterial regulatory networks, making it valuable for studies in bacterial physiology and the development of new antimicrobial strategies. -
Bacterial Inhibitor
8-Epidiosbulbin E acetate is a furanoid compound derived from Dioscorea bulbifera L. It functions as a bacterial inhibitor, demonstrating broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. Additionally, it has been noted to induce liver injury in murine models, highlighting its potential impact on liver function. This compound is valuable for research involving antibiotic resistance and bacterial pathogenicity. -
Bacterial Inhibitor
FtsZ-IN-10 is a bacterial division inhibitor that targets the assembly of FtsZ, a critical protein involved in bacterial cytokinesis. By binding specifically to Bacillus subtilis FtsZ monomers, FtsZ-IN-10 disrupts their polymerization, ultimately hindering the formation of the Z ring and inhibiting cell division. This compound has demonstrated efficacy against antibiotic-resistant clinical isolates, including Staphylococcus aureus and Enterococci, making it a valuable tool in microbiological research and antibiotic development. Additionally, FtsZ-IN-10 may stimulate nucleotide-free archaeal FtsZ to form structured polymers, contributing to its versatile applications in studying bacterial growth and division mechanisms. -
Bacterial Inhibitor
Ianthelliformisamine C ditrifluoroacetate is a bacterial inhibitor that enhances the activity of antibiotics against resistant Gram-negative bacteria. This compound has been shown to significantly improve the efficacy of doxycycline against Pseudomonas aeruginosa. Its mechanism of action involves inducing ATP efflux and causing membrane depolarization in bacterial cells. Ianthelliformisamine C ditrifluoroacetate is synthesized using peptide coupling, resulting in high chemical yields ranging from 27% to 91%, making it a valuable tool for research in combating antibiotic resistance. -
Bacterial Inhibitor
Protactin is a pentapeptide lactone that targets bacterial growth, derived from the Streptomyces cucumeris strain L703-4 (ATCC 53784). This compound demonstrates significant antioxidant properties and can be converted to actinomycin Zp through ferrocyanide oxidation, which displays potent antibacterial activity in vitro. Additionally, actinomycin Zp has been shown to possess substantial antitumor effects against P-388 leukemia in murine models, making it a valuable reagent for cancer research and microbiological studies. -
Bacterial Inhibitor
Cyclo(Leu-Ala) is a cyclic dipeptide with demonstrated antimicrobial properties targeting bacterial pathogens. This compound exhibits significant inhibitory activity against various plant pathogens, making it a valuable tool in studies involving plant-microbe interactions and the development of novel antimicrobial agents. Its potential applications include agricultural research and the investigation of natural products for controlling plant diseases. -
Bacterial Inhibitor
Haplopine is a bacterial inhibitor that exhibits photo-activated antimicrobial properties. It demonstrates the ability to bind to DNA, making it a valuable tool for research applications focused on bacterial infections and microbial resistance. This compound is beneficial in studies investigating the mechanisms of antimicrobial action and the potential development of novel therapeutic strategies. -
Bacterial Inhibitor
Forphenicinol is a bacterial inhibitor that acts as an immunomodulator, derived from the bacterial metabolite forphenicine. It enhances the phagocytic activity of peritoneal macrophages and is effective in mitigating cyclophosphamide-induced suppression of delayed-type hypersensitivity (DTH) in murine models. Forphenicinol increases macrophage bactericidal activity against Pseudomonas aeruginosa and improves survival rates in mouse models of P. aeruginosa infection. Additionally, it demonstrates anti-tumor effects in S180 sarcoma and IMC carcinoma xenograft models, with effective dosing ranging from 0.05 to 5 mg/kg per day. -
Bacterial Inhibitor
Glyasperin D is a flavonoid derived from Glycyrrhiza uralensis that demonstrates antibacterial properties, specifically as a bacterial inhibitor against Helicobacter pylori. Its biological activity suggests potential applications in research focused on bacterial infections and the development of antibacterial agents. This compound may serve as a valuable tool in studying H. pylori-related diseases and exploring flavonoid mechanisms in bacterial inhibition. -
Bacterial Inhibitor
JM 1397 is a potent antibacterial agent with a primary mechanism of action against bacterial pathogens. It demonstrates significant antibacterial activity against both methicillin-susceptible and methicillin-resistant Staphylococcus aureus, with a minimum inhibitory concentration (MIC90) of 1 μg/mL. This compound is valuable for research in antibiotic resistance and the development of new antimicrobial therapies. -
Bacterial Inhibitor
Gyramide A is a bacterial inhibitor that targets bacterial topoisomerases. It has been shown to exhibit a unique mechanism of action distinct from other topoisomerase inhibitors, highlighting its potential in studies related to bacterial resistance. Gyramide A is valuable for research applications aimed at understanding the protective effects of Qnr proteins on bacterial enzymes and developing novel antibacterial strategies. -
Bacterial Inhibitor
MT0703 is an aminothiazolyl glycyl cephalosporin that targets bacterial pathogens, exhibiting potent anti-Pseudomonas activity. This compound is studied for its potential in understanding bacterial resistance mechanisms and developing novel therapeutic strategies. Its structure, featuring a 1,5-dihydroxy-4-pyridone-2-carbonyl group, enhances its efficacy against a range of bacterial infections. -
ATPase/Bacterial Inhibitor
Dihydronovobiocin is a bacterial inhibitor that targets ATPase activity by binding to the GyrB subunit of DNA gyrase. This compound is useful for investigating the interactions between coumarin antibiotics, such as Novobiocin, Chlorobiocin, and Coumermycin, and their effects on DNA gyrase function. Dihydronovobiocin also has potential applications in the study of bacterial infections, facilitating research into the mechanisms of antibiotic action and resistance. -
Bacterial Inhibitor
(4-Aminobenzyl)phosphonic acid is a bioactive compound that acts as a bacterial inhibitor. It exhibits notable antibacterial and potential anticancer activities, making it useful in various research applications, particularly in the synthesis of new compounds aimed at inhibiting bacterial growth. Its unique structural properties enable effective interaction with biological targets, facilitating the exploration of novel therapeutic strategies. -
Bacterial Inhibitor
MGB-BP-3 is a bacterial inhibitor that targets multi-resistant Gram-positive pathogens. This antibiotic exhibits potent activity across a variety of clinically relevant bacterial strains, making it a valuable tool for studies focused on combating antibiotic resistance. Its broad-spectrum efficacy supports research applications in antibiotic development and microbiology. -
Bacterial Inhibitor
Gramicidin C is a polypeptide antibiotic with a primary mechanism of action as a bacterial inhibitor. It disrupts bacterial cell membrane function, resulting in increased permeability that leads to cell lysis. This compound is widely utilized in microbiology research to study bacterial resistance mechanisms and to investigate antibiotic efficacy against various gram-positive and gram-negative bacteria. -
Bacterial Inhibitor
Anhydroerythromycin A is a bacterial inhibitor derived from the degradation of the macrolide antibiotic erythromycin. It exhibits antimicrobial activity against Staphylococcus aureus and Bacillus cereus, with minimum inhibitory concentrations of 12.5 µg/ml and 6.25 µg/ml, respectively. Additionally, Anhydroerythromycin A inhibits steroid 6β-hydroxylase activity linked to the cytochrome P450 isoform CYP3A in human liver microsomes, making it a valuable tool for studying bacterial resistance and metabolic pathways. -
Bacterial Inhibitor
Cefsulodin is a bacterial inhibitor primarily targeting Pseudomonas aeruginosa. It exhibits potent antimicrobial activity against penicillin-susceptible and gentamicin-sensitive strains, demonstrating effectiveness comparable to gentamicin and debendazole. However, Cefsulodin's efficacy is reduced against penicillin-resistant strains of P. aeruginosa, particularly those also resistant to gentamicin. The compound shows a similar minimum inhibitory concentration for P. aeruginosa maltofila when compared to penicillin, gentamicin, and debendazole, while Pseudomonas cepacia strains typically present moderate resistance to Cefsulodin. Its applications include evaluating bacterial resistance mechanisms and antibiotic efficacy in clinical microbiology. -
Bacterial Inhibitor
Ampicillin is a broad-spectrum beta-lactam antibiotic that targets bacterial cell wall synthesis by inhibiting penicillin-binding proteins. It is effective against a wide range of gram-positive and gram-negative bacteria, making it a valuable reagent in microbiological research and antibiotic susceptibility testing. Ampicillin is commonly used to study bacterial resistance mechanisms and is also employed in molecular biology for the selection of recombinant plasmids in cloning applications. -
SPT Inhibitor
Myriocin is a potent serine palmitoyltransferase (SPT) inhibitor derived from various fungal species such as Myriococcum albomyces, Isaria sinclairi, and Mycelia sterilia. By inhibiting SPT, Myriocin plays a crucial role in the disruption of de novo sphingolipid synthesis. It has demonstrated significant antiviral activity, effectively suppressing the replication of both the subgenomic HCV-1b replicon and the JFH-1 strain of genotype 2a infectious HCV, with an IC50 of 3.5 μg/mL. This compound is valuable for research into sphingolipid metabolism and hepatitis C virus infection mechanisms. -
Bacterial Inhibitor
Acorafloxacin hydrochloride is a broad-spectrum fluoroquinolone antibacterial agent that targets bacterial DNA gyrase and topoisomerase IV. It exhibits potent activity against a range of Gram-positive bacteria, with a mean MIC90 value of 0.12 mg/L. This compound is particularly relevant for research on acute bacterial skin infections and community-acquired pneumonia, as well as the investigation of methicillin-resistant Staphylococcus aureus (MRSA) infections. -
Bacterial Inhibitor
Targeting the bacterial sliding clamp peptide 46 is a short peptide designed to inhibit the bacterial sliding clamp (SC). By interfering with SC-dependent DNA synthesis, this peptide serves as a valuable tool for studying bacterial replication mechanisms and developing novel antibacterial strategies. Its application in research underscores its potential utility in exploring bacterial growth and resistance pathways. -
Bacterial Inhibitor
Cephabacin M6 is a 7-methoxydesacetylcephalosporin that acts as a bacterial inhibitor. It is isolated from the culture filtrate of Xanthomonas lactamica and exhibits significant antibacterial activity against various bacterial strains. This compound is useful in microbiological research for studying antibiotic mechanisms and resistance patterns in bacteria. -
Bacterial Inhibitor
Lascufloxacin hydrochloride is a potent antibacterial compound that targets bacterial DNA gyrase and topoisomerase IV, exhibiting broad-spectrum activity against diverse clinical isolates. It demonstrates robust efficacy against Gram-positive bacteria, outperforming other quinolone derivatives. Notably, Lascufloxacin hydrochloride shows incomplete cross-resistance to certain quinolone-resistant strains, making it a valuable candidate for further investigation. Its ability to inhibit both wild-type and mutated target enzymes underscores its potential in tackling resistant bacterial infections in research settings. -
Bacterial Inhibitor
Antibacterial Agent 63 is a conjugate of aztreonam and a siderophore mimetic, designed to inhibit gram-negative bacteria. This compound exhibits a significant antibacterial activity by targeting bacterial cell wall synthesis, providing a mechanism that enhances its effectiveness against resistant strains. It is suitable for research applications aimed at studying bacterial infections and antibiotic resistance mechanisms. -
Bacterial Inhibitor
DA-7867 is an antibacterial compound that targets a broad spectrum of bacterial strains, including those that are drug-resistant. This amide analog of Tedizolid demonstrates significant antibacterial activity against key clinically relevant pathogens, highlighting the potential of tetrazoles in the discovery of novel antibacterial agents. Its efficacy makes DA-7867 a valuable tool for research into bacterial infections and antibiotic resistance. -
Bacterial Inhibitor
Ro 24-6392 is an ester-linked co-drug that combines Ciprofloxacin and Desacetylcefotaxime, targeting inhibition of bacterial growth. It demonstrates potent antibacterial activity against a range of aerobic bacteria in vitro, making it a valuable tool for microbiological research and studies focused on bacterial resistance mechanisms. This compound can be utilized in the development of novel antibacterial therapies and for evaluating bacterial susceptibility to co-drug formulations. -
Bacterial Inhibitor
Apalcillin is a bacterial inhibitor designed to target and disrupt the activity of various gram-negative bacteria, particularly those that produce β-lactamase. In combination with Ro 48-1220, a β-lactamase inhibitor, Apalcillin exhibits broad-spectrum activity, effectively inhibiting strains such as Moraxella catarrhalis, Haemophilus influenzae, and Neisseria gonorrhoeae, with minimum inhibitory concentrations as low as 11 μg/mL. This combination also shows significant effectiveness against Pseudomonas aeruginosa and Stenotrophomonas maltophilia at even lower MICs (0.25 to 4 μg/mL). However, its efficacy against certain gram-positive organisms remains limited, making it a valuable tool for research on β-lactamase resistance. -
Bacterial Inhibitor
Phenyl(9H-purin-6-yl)amine is an antibacterial compound that targets bacterial growth by inhibiting various cellular processes. This reagent exhibits significant antibacterial activity and is useful in the development of novel antibacterial agents. Its potential inhibitory effects make it a valuable tool for medical research focused on combating bacterial infections. -
Bacterial Inhibitor
Radicinol is a bacterial inhibitor derived from the metabolite of Cochliobolus lunata. It demonstrates potent antimicrobial activity, particularly against various strains of bacteria, making it a valuable tool for research in microbiology and drug development. Radicinol can be utilized to study bacterial resistance mechanisms and assess the efficacy of new antibacterial agents.
