RIP Kinase

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  1. Necrostatin-1

    Catalog No. A11973
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    RIPK1 inhibitor
    Necrostatin-1 is an ATP-competitive, allosteric inhibitor of receptor-interacting protein kinase 1 (RIPK1) (EC50 = 182 nM). Learn More
  2. GSK481

    Catalog No. A12615
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    RIP1 inhibitor
    GSK481 is a novel benzoxazepinone (BOAz) series of RIP1 inhibitors. Receptor Interacting Protein Kinase 1 (RIP1) has been implicated as a key contributor to inflammation through the regulation of programmed necrosis. Inhibition of this kinase has been shown to hinder cell necrotic death, thereby establishing RIP1 as a viable target for the potential treatment of multiple inflammatory diseases. Learn More
  3. GSK583

    Catalog No. A16311
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    RIP2 kinase inhibitor
    GSK583 is a highly potent and selective inhibitor of RIP2 Kinase. Learn More
  4. RIP2 kinase inhibitor 1

    Catalog No. A16312
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    RIP2 kinase inhibitor
    RIP2 kinase inhibitor 1 is a receptor interacting protein-2 (RIP2) kinase inhibitor extracted from patent WO/2014043446 A1, compound example 1. Learn More
  5. RIP2 kinase inhibitor 2

    Catalog No. A16313
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    RIP2 kinase inhibitor
    RIP2 kinase inhibitor 2 is a receptor interacting protein-2 (RIP2) kinase inhibitor extracted from patent WO/2014043437 A1, compound example 9. Learn More

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