HDAC1 | Adooq Bioscience

Cat. No.: A11153

CAS No.: 1339928-25-4

Fimepinostat (CUDC-907)

Synonyms: CUDC907

CUDC-907 (Fimepinostat) is a single small molecule inhibitor that targets both PI3K and HDAC. CUDC-907 is more efficacious than either a single PI3K or HDAC inhibitor reference compound or a combination of the two single agents at maximally tolerated doses.

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2 mg

$30.00

5 mg

$55.00

All 8 sizes

Cat. No.: A10611

CAS No.: 209783-80-2

Entinostat (MS-275)

Synonyms: SNDX-275; MS-275

MS-275 (Entinostat) is a potent HDAC inhibitor with IC50 of 0.3 and 8uM for HDAC1 and HDAC3, respectively.

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5 mg

$30.00

10 mg

$35.00

All 7 sizes

Cat. No.: A11920

CAS No.: 128517-07-7

Romidepsin (FK228, Depsipeptide)

Synonyms: FK228; Depsipeptide

Romidepsin strongly inhibits HDAC1 and HDAC2 with IC5N/A of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC5N/A 25 nM and 79N/A nM, respectively.

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1 mg

$90.00

2 mg

$145.00

All 7 sizes

Cat. No.: A17323

CAS No.: 99-66-1

Valproic acid

Synonyms: Depakin; Erganyl; Stavzor; Valproate

Valproic acid is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2; Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.

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500 mg

$35.00

1 g

$45.00

All 5 sizes

Cat. No.: A15934

CAS No.: 1375465-91-0

ACY-738

ACY-738 is a potent and selective HDAC6 inhibitor with improved brain bioavailability. ACY-738 inhibits HDAC6 with low nanomolar potency and a selectivity of 60- to 1500-fold over class I HDACs.

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1 mg

$35.00

2 mg

$50.00

All 8 sizes

Cat. No.: A10516

CAS No.: 404951-53-7

Dacinostat (LAQ824, NVP-LAQ824)

Synonyms: LAQ824; NVP-LAQ824

LAQ824 (NVP-LAQ824) is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.

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1 mg

$40.00

2 mg

$55.00

All 9 sizes

Cat. No.: A10947

CAS No.: 58880-19-6

Trichostatin A (TSA)

Synonyms: TSA

Trichostatin A (TSA) inhibits the HDACs 1, 3, 4, 6 and 10 with IC50 values around 20 nM.

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1 mg

$70.00

2 mg

$105.00

All 8 sizes

Cat. No.: A10488

CAS No.: 732302-99-7

ITF2357 (Givinostat)

Synonyms: Gavinostat

ITF2357 (Givinostat) is a HDACs inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities.

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5 mg

$35.00

10 mg

$65.00

All 7 sizes

Cat. No.: A10830

CAS No.: 929016-96-6

Pracinostat (SB939)

Synonyms: SB-939

SB939 is an oral inhibitor of HDAC, selective for class I, II and IV HDACs and displays an IC50 value of 77 nM in an in vitro HDAC1 activity assay.

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5 mg

$85.00

10 mg

$125.00

All 6 sizes

Cat. No.: A16431

CAS No.: 1045792-66-2

CAY10603

CAY10603 is a potent and selective HDAC6 inhibitor with IC50 of 2 pM, >200-fold selectivity over other HDACs.

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1 mg

$45.00

2 mg

$70.00

All 8 sizes

Cat. No.: A10518

CAS No.: 404950-80-7

Panobinostat (LBH589)

Synonyms: NVP-LBH589; LBH589

LBH589 is a hydroxamic acid and acts as a non-selective HDAC inhibitor with IC5o of HDAC1 to be 0.23 nM.

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5 mg

$25.00

10 mg

$45.00

All 8 sizes

Cat. No.: A10700

CAS No.: 783355-60-2

Abexinostat (PCI-24781)

Synonyms: CRA-024781; PCI-24781

PCI-24781 is a broad-spectrum phenyl hydroxamic acid HDAC inhibitor.

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1 mg

$25.00

2 mg

$40.00

All 8 sizes

Cat. No.: A15437

CAS No.: 604769-01-9

R306465

Synonyms: JNJ-16241199

R306465 is a novel hydroxamate-based histone deacetylase (HDAC) inhibitor with broad-spectrum antitumour activity against solid and haematological malignancies in preclinical models.

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1 mg

$130.00

2 mg

$195.00

All 5 sizes

Cat. No.: A10586

CAS No.: 726169-73-9

Mocetinostat (MGCD0103)

Synonyms: MGCD0103

MGCD0103 (Mocetinostat) is a benzamide histone deacetylase inhibitor by inhibiting mainly histone deacetylase 1 (HDAC1), but also HDAC2, HDAC3, and HDAC11.

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5 mg

$30.00

10 mg

$45.00

All 7 sizes

Cat. No.: A10492

CAS No.: 875320-29-9

Quisinostat (JNJ-26481585)

Synonyms: JNJ-26481585

JNJ-26481585 (Quisinostat) is a pan-HDAC inhibitor with marked potency toward HDAC1 (IC(50), 0.16 nmol/L).

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1 mg

$45.00

2 mg

$70.00

All 8 sizes

Cat. No.: A10979

CAS No.: 149647-78-9

Vorinostat (SAHA)

Synonyms: Zolinza; MK-0683; SAHA

Vorinostat is an inhibitor of HDACs, inhibiting deacetylation and leading to an accumulation of both hyperacetylated histones and transcription factors.