AR-42 (HDAC-42)

Catalog No.: A11037

HDAC inhibitor

AR-42 (HDAC-42)

AR-42 (HDAC-42) Chemical Structure

CAS NO. 935881-37-1

AR-42 is a novel HDAC inhibitor, exhibits biologic activity against malignant mast cell lines via down-regulation of constitutively activated Kit.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$150.00
25 mg
$300.00
50 mg
$550.00
10mM * 1mL in DMSO
$109.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Yong-Hui Liao, .et al. Histone deacetylase 2 is involved in μ-opioid receptor suppression in the spinal dorsal horn in a rat model of chronic pancreatitis pain, Mol Med Rep, 2018, Feb; 17(2): 2803-2810 PMID: 29257262

Biological Activity

AR-42 is a novel HDAC inhibitor, exhibits biologic activity against malignant mast cell lines via down-regulation of constitutively activated Kit.
Targets
HDAC
30 nM
In vitro (25°C) DMSO 63 mg/mL (201.69 mM)
Water <1 mg/mL (<1 mM)
Ethanol 63 mg/mL (201.69 mM)
In vivo 0.5% methylcellulose/0.2% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.01 mL 160.05 mL 320.1 mL
0.5 mM 6.4 mL 32.01 mL 64.02 mL
1 mM 3.2 mL 16.01 mL 32.01 mL
5 mM 0.64 mL 3.2 mL 6.4 mL

*The above data is based on the productmolecular weight 312.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11037
Actions Inhibitor
M. Wt 312.4
Formula C18H20N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 935881-37-1
Synonyms AR42, OSU-HDAC42
SMILES CC(C)[[email protected]@H](C1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)C(=O)NO

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