ITF2357 (Givinostat)

ITF2357 (Givinostat) is a HDACs inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities.
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ITF2357 5mg
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ITF2357 10mg
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ITF2357 50mg
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ITF2357 100mg
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ITF2357 (Givinostat) 10mM * 1mL in DMSO
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Adooq Products cited in reputable paper
Adooq's ITF2357 (Givinostat) has been cited by 1 publications
  • Flavien Bizot, .et al. , Mol Ther Nucleic Acids, 2022, Nov 21;30:606-620 PMID: 36514350
  • Biological Activity
    Discription ITF2357 (Givinostat) is a HDACs inhibitor with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities.
    Target Value
    Product Information
    Catalog Num A10488
    Formula C24H27N3O4.HCl.H2O
    Molecular Weight 476
    CAS Number 732302-99-7
    SMILES CC[NH+](CC)CC1=CC2=C(C=C1)C=C(C=C2)COC(=O)NC3=CC=C(C=C3)C(=O)NO.O.[Cl-]
    Synonyms Gavinostat

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO 94 mg/mL (197.49 mM)
    Water Insoluble
    Ethanol 3 mg/mL
    In vivo 5%DMSO+40%PEG300++5%Tween80+50%ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 21.01 mL 105.04 mL 210.08 mL
    0.5 mM 4.2 mL 21.01 mL 42.02 mL
    1 mM 2.1 mL 10.5 mL 21.01 mL
    5 mM 0.42 mL 2.1 mL 4.2 mL
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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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