5-HT Receptors

Cat. No.

A29431

CAS No.

65527-62-0

ETH-LAD

Synonyms: N-Ethyl-nor-LSD

ETH-LAD (N-Ethyl-nor-LSD) is a selective activator of the 5-HT2A receptor, exhibiting a binding affinity with a Ki value of 5.1 nM. Additionally, it demonstrates affinity for dopamine receptors D1 and D2, with Ki values of 22.1 nM and 4.4 nM, respectively. ETH-LAD is utilized in research exploring psychoactive effects and receptor pharmacology in various models, including rat studies.

Cat. No.

A29852

CAS No.

776-56-7

5-Fluoro-α-methyltryptamine hydrochloride

5-Fluoro-α-methyltryptamine hydrochloride is a potent 5-HT activator that enhances intracellular levels of serotonin (5-HT) and subsequently promotes its release. This compound demonstrates significant efficacy with EC50 values of 37 nM for dopamine (DA), 14 nM for serotonin (5-HT), 78 nM for norepinephrine (NE), and 8.47 nM for the 5-HT2A receptor. Its application in research includes studying serotonin-related pathways and neuropharmacological effects, making it valuable for investigations in behavioral science and psychiatric disorders.

Cat. No.

A29935

CAS No.

65527-61-9

AL-LAD

Synonyms: 6-Allyl-6-nor-LSD

AL-LAD, or 6-Allyl-6-nor-LSD, is a potent activator of the 5-HT2A receptor, exhibiting a Ki value of 3.4-8.1 nM. Additionally, it demonstrates notable affinity for dopamine D1 and D2 receptors, with K0.5 values of 189 nM and 12.3 nM, respectively. AL-LAD's psychoactive properties have been investigated in mouse models, making it a valuable tool for research in neuropharmacology and the study of serotonergic and dopaminergic pathways.