Leukotriene Receptor

Cat. No.

A61045

CAS No.

80445-66-5

Leukotriene B5

Synonyms: LTB5

Leukotriene B5 (LTB5) is a leukotriene receptor activator, primarily influencing inflammatory responses. As a metabolite of eicosapentaenoic acid produced via the 5-lipoxygenase (5-LO) pathway, LTB5 is known to increase the contraction of bullfrog lung strips in a concentration-dependent manner. In vivo studies demonstrate that LTB5 (100 nM) can significantly reduce tumor volume in mice with Tm1 murine melanoma cells. Additionally, LTB5 induces chemokinesis and lysosomal enzyme release from polymorphonuclear leukocytes at significantly lower levels compared to LTB4, and exhibits reduced platelet aggregation.

Cat. No.

A61067

CAS No.

5067-25-4

ST026567

ST026567 is a potent mast cell activator that functions by inducing the secretion of prostaglandin D2 (PGD2) and leukotriene C4 (LTC4) from mast cells. This compound exhibits strong degranulation activity, making it a valuable tool for studies focused on mast cell biology and allergic responses. Research applications include investigations into inflammatory processes and the development of potential therapeutic strategies targeting mast cell-related disorders.