Catalog No.
Product Name
Application
Product Information
Citations
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Stable Isotope
trans-Cinnamic acid-d5 is a deuterium-labeled derivative of trans-Cinnamic acid, a naturally occurring compound known for its antimicrobial properties. This stable isotope can be utilized in various research applications, including pharmacokinetic studies and metabolic profiling. It exhibits a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen Aeromonas sobria, SY-AS1, making it a valuable reagent for studies related to antimicrobial efficacy and resistance. -
Stable Isotope
1-Tetradecanol-d2 is a deuterium-labeled variant of 1-Tetradecanol, a straight-chain saturated fatty alcohol derived from Myristica fragrans. This compound exhibits notable antibacterial and anti-inflammatory properties, specifically in the context of periodontitis. It serves as a valuable stable isotope in research applications involving metabolic studies, lipid metabolism, and the investigation of fatty alcohols’ roles in biological systems. -
Stable Isotope
Valacyclovir-d4 hydrochloride is a deuterated form of the antiviral agent Valacyclovir hydrochloride, designed for use as a stable isotope in research applications. It effectively inhibits herpes simplex virus type 1 (HSV-1) with a half-maximal inhibitory concentration (IC50) of 2.9 μg/ml. This compound serves as a prodrug to Acyclovir, allowing for effective studies on antiviral mechanisms and pharmacokinetics in virology and medicinal chemistry research. -
Stable Isotope
Trimethoprim-13C3 is a stable isotope-labeled variant of Trimethoprim, a potent bacteriostatic antibiotic that acts primarily as a dihydrofolate reductase inhibitor. This compound exhibits significant activity against a variety of Gram-positive and Gram-negative aerobic bacteria and is employed in research focused on conditions such as urinary tract infections, Shigellosis, and Pneumocystis pneumonia. Additionally, Trimethoprim has been shown to inhibit Influenza A virus infection in chick embryos when used in conjunction with zinc, making it a valuable tool for studies related to antimicrobial and antiviral therapies. -
Stable Isotope
Iclaprim-d6 is a deuterium-labeled derivative of Iclaprim, a selective inhibitor of bacterial dihydrofolate reductase. This compound effectively inhibits the growth of methicillin-resistant Staphylococcus aureus (MRSA) with a minimal inhibitory concentration (MIC90) of 0.06 μg/mL. Iclaprim-d6 serves as a valuable tool for research applications involving antibiotic resistance and the mechanisms of bacterial growth inhibition. -
Stable Isotope
Tedizolid-13C,d3 is a stable isotope-labeled form of Tedizolid, which is an oxazolidinone antibiotic. Its primary mechanism involves the inhibition of bacterial protein synthesis by binding to the 23S ribosomal RNA component of the 50S ribosomal subunit. This compound is essential for research applications in studying antibiotic resistance, ribosomal function, and the pharmacokinetics of Tedizolid in various biological systems. -
Stable Isotope
Erythromycin-d6 is a deuterium-labeled analog of Erythromycin, a macrolide antibiotic derived from the actinomycete Streptomyces erythreus. This compound exhibits broad-spectrum antimicrobial activity by binding to the 50S ribosomal subunit of bacteria, thereby inhibiting RNA-dependent protein synthesis through the blockade of transpeptidation and translocation processes. Erythromycin-d6 is valuable for research applications in pharmacokinetics and metabolic studies, particularly in tracing and quantifying the pharmacological behavior of Erythromycin in various biological systems. -
Stable Isotope
Cefazolin-13C2,15N sodium is a stable isotope-labeled derivative of the first-generation cephalosporin antibiotic, Cefazolin. This reagent is designed for advanced research in bacterial infections, leveraging its antimicrobial properties. Additionally, Cefazolin has demonstrated anti-inflammatory effects, making it valuable for studies related to postoperative cognitive dysfunction (POCD) and other inflammatory conditions. -
Stable Isotope
Orbifloxacin-d4 is a deuterated derivative of Orbifloxacin, functioning as a stable isotope tracer in biological research. This compound is utilized for pharmacokinetic studies and metabolic tracing, providing insights into drug metabolism and pharmacodynamics. Its isotopic labeling allows for enhanced detection and quantification in various analytical assays. -
Stable Isotope
Gatifloxacin-d4 is a deuterium-labeled derivative of the fluoroquinolone antibiotic Gatifloxacin, which primarily targets bacterial topoisomerases II. It exhibits broad-spectrum antibacterial activity, with IC50 values of 13.8 μg/mL against S. aureus topoisomerase IV and 0.109 μg/mL for E. coli DNA gyrase. This stable isotope-labeled compound is suitable for investigative research into bacterial infections, particularly in studies related to bacterial conjunctivitis. -
Stable Isotope
trans-Cinnamic acid-d7 is a deuterium-labeled derivative of trans-Cinnamic acid, enabling enhanced tracking in metabolic studies. This compound exhibits natural antimicrobial properties, demonstrating a minimal inhibitory concentration (MIC) of 250 μg/mL against the fish pathogen Aeromonas sobria, strain SY-AS1. It is primarily utilized in biochemical research to study metabolic pathways and antimicrobial efficacy. -
Stable?Isotope
Lactate-d3 sodium (60% w/w in water) is a stable isotope of lactic acid sodium that acts as a hydroxycarboxylic acid receptor 1 (HCAR1) activator and serves as an epigenetic modulator through the lactylation of lysine residues. This compound is a key end-product of glycolysis, linking metabolic processes such as glycolysis and oxidative phosphorylation. Additionally, it plays a significant role in tumor metabolism and has been implicated in enhancing anti-tumor immunity. Lactate-d3 sodium also exhibits antimicrobial properties, making it suitable for use in food preservation. -
Stable Isotope
Lauric acid-d23 is a deuterium-labeled derivative of lauric acid, a medium-chain fatty acid known for its potent bactericidal properties. This compound exhibits strong antimicrobial activity, with effective concentration (EC50) values of 2 μg/mL against Propionibacterium acnes, 6 μg/mL against Staphylococcus aureus, and 4 μg/mL against Staphylococcus epidermidis. Lauric acid-d23 is valuable for use in biochemical research, particularly in studies exploring lipid metabolism and the antimicrobial mechanisms of fatty acids. -
Stable Isotope
Nonanoic acid-d17 is a deuterium-labeled derivative of nonanoic acid, a naturally occurring saturated fatty acid with nine carbon atoms. This compound serves as a stable isotope and is utilized in metabolic studies and tracer experiments. Nonanoic acid exhibits significant antibacterial activity, reduces bacterial translocation, and enhances the secretion of porcine β-defensins 1 (pBD-1) and pBD-2, making it valuable for research in antimicrobial mechanisms and gut health. -
Stable Isotope
Hexadecane-d34 is a deuterium-labeled stable isotope of hexadecane, a saturated hydrocarbon belonging to the alkane family. This compound serves as a valuable organic solvent and is a key component of petroleum. Hexadecane-d34 is primarily used in research applications focused on understanding the bacterial degradation of hydrophobic compounds, making it an important tool in environmental and biochemical studies. -
Stable Isotope
Lauric acid-d3 is a deuterium-labeled derivative of lauric acid, a medium-chain fatty acid noted for its potent bactericidal activity. It exhibits effective antimicrobial properties, with EC50 values of 2 μg/mL for Propionibacterium acnes, 6 μg/mL for Staphylococcus aureus, and 4 μg/mL for Staphylococcus epidermidis. Lauric acid-d3 is primarily utilized in tracer studies and metabolic research to investigate fatty acid metabolism and functions in various biochemical pathways. -
Stable?Isotope
Lactate-d4 sodium (60% w/w in water) is a deuterium-labeled derivative of lactic acid, targeting hydroxycarboxylic acid receptor 1 (HCAR1) for its biological activity. This compound serves as an epigenetic modulator, promoting lactylation of lysine residues and functioning as an important glycolytic end-product linking glycolysis and oxidative phosphorylation. As an oncometabolite, lactate-d4 sodium has demonstrated roles in anti-tumor immunity while also exhibiting antimicrobial properties that may be applied in food preservation. Its stable isotope labeling makes it a valuable tool for metabolic studies and tracer experiments. -
Stable Isotope
Lauric acid-13C is a stable isotope-labeled version of lauric acid, a medium-chain fatty acid recognized for its potent bactericidal activity. Its effectiveness is demonstrated by EC50 values of 2 μg/mL against Propionibacterium acnes, 6 μg/mL against Staphylococcus aureus, and 4 μg/mL against Staphylococcus epidermidis. This reagent is useful for metabolic tracing studies and examining fatty acid metabolism in various biological contexts. -
Stable Isotope
4-Hydroxybenzoic acid-d4 is a deuterium-labeled analog of 4-Hydroxybenzoic acid, a phenolic compound that serves as a potent antimicrobial agent. This compound demonstrates inhibitory activity against a variety of gram-positive bacteria as well as certain gram-negative strains, exhibiting an IC50 value of 160 μg/mL. It is primarily utilized in metabolic studies and as a stable isotope for biochemical applications. -
Stable Isotope
Omadacycline-d9 is a deuterium-labeled derivative of Omadacycline, designed for use as a stable isotope internal standard in analytical applications. This compound serves as a valuable tool for quantifying Omadacycline levels in biological samples, facilitating accurate pharmacokinetic studies and metabolic profiling. Researchers can leverage Omadacycline-d9 to enhance the reliability of their assays in drug development and therapeutic monitoring. -
Stable Isotope
Maleic acid-d2 is a deuterium-labeled derivative of maleic acid, which serves as a stable isotope for research applications. It functions primarily as an inhibitor of glutamate decarboxylase (GAD) in organisms such as E. coli and L. monocytogenes, making it useful for studies related to neurotransmitter regulation and bacterial metabolism. This compound is valuable in the fields of metabolic research and biochemical assays. -
Stable Isotope
L-Lactic acid-13C-1 sodium serves as a stable isotope-labeled precursor for various biochemical applications, including the study of metabolic pathways and biopolymer synthesis. This compound demonstrates key biological activity by exhibiting antiproliferative effects, making it valuable for research involving cancer metabolism and tissue engineering. Additionally, L-Lactic acid-13C-1 sodium is essential for the production of the biodegradable polymer poly-lactic acid, contributing to advancements in sustainable materials research. -
Stable Isotope
Vitamin D3-d3 is a deuterium-labeled form of Vitamin D3 (Cholecalciferol), a naturally occurring vitamin essential for various biological functions. This stable isotope is utilized in metabolic studies and tracer experiments to investigate Vitamin D3 metabolism, mechanisms of action, and its role in cellular differentiation and inhibition of cancer cell proliferation. Its applications extend to research in endocrinology, oncology, and nutrition. -
Stable Isotope
(±)-Leucine-d10 is a deuterium-labeled form of (±)-Leucine, which serves as a stable isotope. This compound exhibits significant growth inhibition of Escherichia coli HfrH by 92.08%, making it a valuable tool for studying metabolic pathways and protein synthesis. Its applications extend to various fields including biochemical research, nutrition studies, and chemosterilization processes. -
Stable Isotope
DL-3-Phenyllactic acid-d3 is a deuterated derivative of DL-3-Phenyllactic acid, functioning as a stable isotope. This compound exhibits broad-spectrum antimicrobial activity, making it valuable for research in microbiology and pharmacology. Its unique isotopic labeling enables precise tracking and quantification in metabolic studies and helps elucidate biochemical pathways involving phenyl lactate metabolism. -
Stable Isotope
D-Glucose-13C6,d7 is a stable isotope-labeled form of D-Glucose, incorporating both deuterium and carbon-13 isotopes. This compound serves as a valuable tracer in metabolic studies, aiding in the investigation of carbohydrate metabolism and metabolic flux analysis. Its unique isotopic composition allows for precise tracking of glucose utilization in various biological systems, making it a critical reagent for researchers studying energy metabolism and cellular processes. -
Stable Isotope
Sulfamethazine-d4 is a deuterium-labeled derivative of Sulfamethazine, a sulfonamide antibiotic. This stable isotope is primarily used for research applications, including pharmacokinetic studies and metabolic tracing in biological systems. Sulfamethazine itself is utilized for its antimicrobial properties, particularly in treating and preventing gastrointestinal and respiratory infections in animals. -
Stable Isotope
α-Terpineol-d3 is a deuterium-labeled derivative of α-Terpineol, a compound derived from Eucalyptus globulus. This stable isotope retains the strong antimicrobial properties of α-Terpineol, demonstrating significant activity against periodontopathic and cariogenic bacteria, as well as antifungal effects against Trichophyton mentagrophytes. Its unique labeling makes it valuable in research applications focused on microbial interactions and cellular disruption mechanisms. -
Stable Isotope
Nonanoic acid-d4 is a deuterium-labeled derivative of nonanoic acid, a naturally occurring saturated fatty acid with nine carbon atoms. This stable isotope is utilized in various research applications to study metabolic processes and fatty acid metabolism. Nonanoic acid has been shown to significantly reduce bacterial translocation, enhance antibacterial activity, and increase the secretion levels of porcine β-defensins 1 (pBD-1) and pBD-2, making it valuable for investigations into antimicrobial peptides and gut health. -
Stable Isotope
D-Sorbitol-13C6 is a stable isotope-labeled form of D-Sorbitol, a six-carbon sugar alcohol. This compound serves as a versatile stabilizing excipient and isotonicity agent, making it suitable for various formulations. It is often utilized in biological research to trace metabolic pathways and assess carbohydrate metabolism, providing valuable insights into biochemical processes. D-Sorbitol-13C6 is also employed extensively in dietary supplement research and food science applications. -
Stable Isotope
Urethane-d5 is a deuterium-labeled version of Urethane, which is the ethyl ester of carbamic acid. It is commonly utilized in studies involving fermentation and food products. Urethane is known to inhibit the growth of bacteria, protozoa, sea urchin eggs, and plant tissues in vitro, making it valuable for various research applications in microbiology and botany. -
Stable Isotope
Tridecanoic acid-d25 is a deuterated form of tridecanoic acid, a medium-chain saturated fatty acid consisting of 13 carbon atoms. This compound acts as an antipersister and antibiofilm agent, demonstrating significant inhibitory effects on the persistence and biofilm formation of Escherichia coli. Its unique properties make it a valuable tool in research focused on bacterial infections and the development of strategies to combat biofilm-related challenges. -
Stable Isotope
Saccharin-d4 is a deuterium-labeled form of saccharin, a widely used non-caloric artificial sweetener. As a stable isotope, Saccharin-d4 serves as a valuable tracer in metabolic studies and research involving dietary components. Its unique isotopic signature allows for enhanced tracking of saccharin's effects on microbiome modulation and bacteriostatic activity in various biological systems. -
Stable Isotope
Mandelic acid-2,3,4,5,6-d5 is a deuterium-labeled variant of mandelic acid, an alpha-hydroxycarboxylic acid. This stable isotope serves as a valuable tool in tracing studies and metabolic research. Mandelic acid demonstrates antimicrobial properties and has applications in the study of urinary tract infections and vaginal trichomoniasis. Additionally, it is known for its high sperm-immobilizing activity while minimizing vaginal irritation, making it relevant for reproductive health research. -
Stable Isotope
Nonanoic acid-d2 is the deuterium-labeled derivative of nonanoic acid, a saturated fatty acid comprising nine carbon atoms. This compound plays a critical role in metabolic studies and tracing experiments due to its stable isotope labeling. Research indicates that nonanoic acid exhibits significant antibacterial properties, reduces bacterial translocation, and enhances the secretion of porcine β-defensins 1 and 2, making it a valuable tool in studies of intestinal health and antimicrobial peptide function. -
Stable Isotope
Thymol-d13 is a deuterated form of Thymol, a key monoterpene phenol primarily found in essential oils from the Lamiaceae family as well as various other plant families, including Verbenaceae, Scrophulariaceae, Ranunculaceae, and Apiaceae. This stable isotope is utilized in research to trace pathways and quantify metabolites in biological systems. Thymol exhibits notable biological activities, including antioxidant, anti-inflammatory, antibacterial, and antifungal properties, making it relevant for studies in pharmacology and biochemistry. -
Stable Isotope
Octacosane-d58 is the deuterated form of octacosane, a long-chain hydrocarbon with antibacterial properties. This stable isotope is valuable for studies investigating the metabolic pathways and biological activities of octacosane. Notably, octacosane exhibits considerable cytotoxicity against murine melanoma B16F10-Nex2 cells and provides protective effects in subcutaneous melanoma models. Additionally, it demonstrates larvicidal activity against the mosquito Culex quinquefasciatus, with an LC50 of 7.2 mg/L, making it a useful compound for research in both cancer biology and pest control. -
Stable Isotope
Vitamin D3-d7 is a deuterium-labeled form of Vitamin D3 (Cholecalciferol), enabling precise tracking in metabolic studies. It is known to promote cell differentiation and inhibit the proliferation of cancer cells, making it a valuable tool in cancer research. This stable isotope is particularly useful for pharmacokinetic studies and the investigation of vitamin D metabolism in biological systems. -
Stable Isotope
Benzothiazole-d4 is a stable isotope-labeled form of Benzothiazole, a naturally occurring heterocyclic compound. This reagent is widely utilized in biological research due to its diverse activities, including anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral properties. Benzothiazole-d4 is particularly valuable for tracing studies and metabolic profiling in various biological systems. -
Stable Isotope
Butylparaben-d4 is a deuterium-labeled derivative of Butylparaben, an organic compound recognized for its effective antimicrobial properties. This reagent is primarily utilized as a stable isotope in chemical research, allowing for the tracing and quantification of Butylparaben in various applications, including cosmetics, pharmaceuticals, and food products. Its stability and unique labeling make it essential for studying the dynamics of antimicrobial preservation and understanding the compound's behavior in complex matrices. -
Stable Isotope
Ethylparaben-d4 is a deuterium-labeled analog of ethylparaben, primarily utilized as a stable isotope standard in analytical chemistry. This compound serves as an internal standard in mass spectrometry and other analytical techniques, facilitating precise quantification and analysis of ethylparaben and its metabolites in biological samples. Its unique isotopic signature enhances the accuracy of trace-level detection and study of paraben-related biological activity in various research applications. -
Stable Isotope
Robenidine-d8 hydrochloride is a deuterium-labeled analogue of Robenidine hydrochloride, primarily utilized as a stable isotope in research. As an effective anticoccidial agent, it exhibits biological activity against Methicillin-resistant Staphylococcus aureus (MRSA) and Vancomycin-resistant Enterococcus (VRE), with MIC50 values of 8.1 µM and 4.7 µM, respectively. This compound is valuable for studies investigating coccidiosis and antibiotic resistance in bacterial pathogens. -
Stable Isotope
Lauric acid-d2 is a deuterium-labeled form of lauric acid, a medium-chain fatty acid known for its potent bactericidal activity. It exhibits effective antibacterial properties against Propionibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis, with EC50 values of 2, 6, and 4 μg/mL, respectively. This stable isotope is valuable for research applications in microbiology and lipid metabolism studies, enabling the elucidation of fatty acid metabolism and the investigation of antimicrobial mechanisms. -
Stable Isotope
(±)-Leucine-d7 is a deuterium-labeled form of (±)-Leucine, a proteinogenic amino acid. This stable isotope is useful for tracing pathways in metabolic studies, particularly in the analysis of amino acid metabolism and protein synthesis. (±)-Leucine exhibits inhibitory effects on the growth of Escherichia coli HfrH, making it relevant for research involving bacterial cultures and metabolic inhibition. -
Stable Isotope
Triclocarban-d4 is the deuterated form of Triclocarban, a triclocarban compound functioning as a broad-spectrum antibacterial agent. This stable isotope is utilized in various applications, including the formulation of personal care products such as soaps, skin creams, and deodorants. Triclocarban has been identified as a potential endocrine disruptor, capable of affecting androgen and estrogen activity, thereby influencing hormone-mediated biological processes in research studies. -
Isotope-Labeled Compounds
Ethyl acetoacetate-d3 is a deuterium-labeled isotopologue of ethyl acetoacetate. This ester serves as a valuable intermediate in the synthesis of diverse organic compounds. Additionally, ethyl acetoacetate demonstrates bioactivity as an inhibitor of bacterial biofilm formation, making it useful for research applications in microbiology and pharmaceutical development. -
Stable Isotope
Nonanoic acid-d3 is a deuterated analog of nonanoic acid, a naturally occurring saturated fatty acid comprising nine carbon atoms. This stable isotope serves as a useful tracer in metabolic studies and is valuable in research focusing on lipid metabolism, fatty acid absorption, and microbial interactions. Nonanoic acid has been shown to reduce bacterial translocation, enhance antibacterial activity, and increase the secretion of important antimicrobial peptides, specifically porcine β-defensins 1 and 2. -
Stable Isotope
Levulinic acid-d5 is a deuterium-labeled derivative of levulinic acid, primarily used as a stable isotope in chemical research. This compound serves as an important precursor for the synthesis of biofuels, particularly ethyl levulinate, enabling studies on metabolic pathways and the mechanisms of biofuel production. Its unique isotopic labeling facilitates advanced analytical techniques, including mass spectrometry and NMR, making it a valuable tool for researchers in the field of sustainable energy and organic synthesis. -
Stable Isotope
Rac cis-Moxifloxacin-d4 hydrochloride is a deuterated form of the antibiotic moxifloxacin, specifically designed for use as a stable isotope. This compound retains the properties of moxifloxacin, an 8-methoxyquinolone antimicrobial that targets bacterial infections, including acute bacterial sinusitis and pneumonia. Its stable isotope labeling is beneficial for pharmacokinetic studies, metabolic tracking, and the development of analytical techniques in medicinal chemistry. -
Stable Isotope
Clindamycin Hydrochloride-13C,d3 is a stable isotope-labeled form of Clindamycin hydrochloride, incorporating deuterium and 13C. As a semisynthetic lincosamide antibiotic, it inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit. This reagent is valuable for studying drug metabolism, pharmacokinetics, and antibiotic resistance in various biological research applications.
