Cyanine Dyes

Cat. No.

A44857

CAS No.

1782950-80-4

Sulfo-Cy5 azide

Sulfo-Cy5 azide is a near-infrared fluorescent dye that exhibits excellent reactivity in click chemistry reactions. This reagent is primarily utilized for fluorescence imaging and allows for the visualization of PD-L1 expression in tumor tissues and cells. Additionally, Sulfo-Cy5 azide facilitates RNA labeling and can be conjugated to various targeting agents, making it valuable in research applications related to atherosclerosis and breast cancer models.

Cat. No.

A44859

CAS No.

2692677-77-1

Cyanine7 DBCO

Synonyms: Cy7 DBCO

Cyanine7 DBCO is a near-infrared fluorescent dye that acts as an efficient bio-orthogonal quencher. It is generated through the covalent linkage of the Cy7 fluorescent dye and the dibenzocyclooctyne (DBCO) moiety. In biochemical applications, Cyanine7 DBCO significantly decreases the fluorescence of N3-Cy5-COOH by 90% within 90 minutes, with observable signal reduction occurring as quickly as 2-5 minutes. This reagent is ideal for deep tissue imaging and advancing receptor-targeted therapeutic strategies in chemical research.

Cat. No.

A44863

CAS No.

260430-02-2

Cy2

Synonyms: Cyanine2

Cy2 is a fluorescent dye that belongs to the cyanine class of compounds, featuring two nitrogen atoms linked by methene units. It exhibits exceptional optical properties, including long-wavelength absorption and emission with a high extinction coefficient of up to 300,000 M^-1 cm^-1. Cy2 is characterized by good water solubility and ease of synthesis, making it suitable for various applications in in vivo imaging and biological research. Its versatility and robust performance support its use in fluorescence microscopy, cellular imaging, and bioanalytical studies.

Cat. No.

A44865

CAS No.

1432019-64-1

Cy7 NHS ester

Cy7 NHS ester is a fluorescent dye that targets amine groups, facilitating covalent labeling of proteins, peptides, and other biomolecules. This compound exhibits strong near-infrared fluorescence, making it suitable for applications in fluorescent imaging and biological assays. Its properties enable enhanced sensitivity and specificity in the detection and visualization of various biological samples.

Cat. No.

A44868

CAS No.

442912-55-2

Cy5.5-SE

Synonyms: Cyanine5.5 NHS ester

Cy5.5-SE (Cyanine5.5 NHS ester) is a fluorescent dye designed for biochemical labeling applications. It features a long wavelength profile with adjustable absorption and emission, high extinction coefficient, and excellent water solubility, making it suitable for sensitive detection in diverse assays. Cy5.5-SE is commonly used for labeling proteins, antibodies, and small molecular compounds, allowing for straightforward conjugation via a simple mixing method. This dye is ideal for applications in imaging, flow cytometry, and other fluorescence-based techniques.

Cat. No.

A44875

CAS No.

1431148-26-3

Cyanine 5 Tyramide

Synonyms: Tyramide-Cy5

Cyanine 5 Tyramide is a red fluorescent dye that acts as a reporter substrate for horseradish peroxidase (HRP)-catalyzed deposition reactions. This compound is primarily employed in signal amplification techniques in immunoassays and in situ hybridization of nucleic acids. Its high sensitivity makes it suitable for applications requiring enhanced detection of biomolecules in various research settings.

Cat. No.

A44879

CAS No.

1838643-41-6

Cy3 maleimide chloride

Cy3 maleimide chloride is a fluorescent dye derivative of Cyanine 3 (Cy3) featuring maleimide functional groups. It exhibits fluorescence in the green to orange wavelength range and is primarily utilized for labeling biological molecules. The maleimide group facilitates covalent bonding with thiol-containing compounds, allowing for stable conjugation with proteins and antibodies. This property makes Cy3 maleimide chloride an essential tool for tracking protein localization and dynamics in various biological assays and imaging applications.

Cat. No.

A44881

CAS No.

174961-75-2

Cyanine 3 Tyramide

Synonyms: Tyramide-Cy3

Cyanine 3 Tyramide is an orange fluorescent dye that serves as a reporter substrate for horseradish peroxidase (HRP)-catalyzed deposition. This compound plays a crucial role in signal amplification techniques, enhancing the sensitivity of immunoassays and in situ hybridization of nucleic acids. Its effective fluorescence properties make it an invaluable tool for various biological research applications involving protein and nucleic acid detection.

Cat. No.

A44895

CAS No.

1032678-01-5

Cyanine3 carboxylic acid chloride

Cyanine3 carboxylic acid chloride is a red fluorescent dye that exhibits excellent solubility in organic solvents. It serves as a non-toxic, non-reactive fluorophore, making it suitable for experimental control and calibration purposes. Additionally, Cyanine3 carboxylic acid chloride can be conjugated with targeted agents to create fluorescent probes, facilitating the rapid detection of agent interactions in various biological research applications.

Cat. No.

A44900

CAS No.

1881221-50-6

Cy5-PEG3-endo-BCN

Cy5-PEG3-endo-BCN is a fluorochrome dye that features the Cyanine 5 (Cy5) structure with three polyethylene glycol (PEG) units. This compound includes the hydrophilic bidentate macrocyclic ligand endo-BCN, enabling the synthesis of macrocyclic complexes. In the context of click chemistry, endo-BCN readily reacts with azide-containing molecules to form stable triazole linkages without the need for catalytic conditions, making it a valuable tool for bioconjugation and labeling applications in chemical biology and biomedical research.

Cat. No.

A44913

CAS No.

2183440-43-7

Sulfo-Cy3 amine

Synonyms: Sulfo-Cyanine3 amine

Sulfo-Cy3 amine is a fluorochrome dye derived from Cyanine 3 (Cy3) featuring an amine group that enhances its water solubility. This dye exhibits fluorescence in the green to orange wavelength range, making it suitable for diverse biological imaging applications. The amine group can react with carboxyl functionalities, facilitating covalent bonding to proteins and antibodies. Sulfo-Cy3 amine is ideal for tracking molecular localization and dynamic changes in biological samples, providing valuable insight into cellular processes.

Cat. No.

A44918

CAS No.

2270866-73-2

Cy7.5 maleimide

Cy7.5 maleimide is a near-infrared fluorescent (NIRF) dye that targets thiol groups for protein labeling. Characterized by its long wavelength and high extinction coefficient, this cyanine dye exhibits excellent water solubility and can be synthesized easily. Cy7.5 maleimide is particularly useful for the labeling of proteins, antibodies, and small molecules, facilitating a straightforward mixing reaction for conjugation. Its properties make it an ideal choice for applications in in vivo imaging, biomolecular studies, and diagnostics.

Cat. No.

A44921

CAS No.

1032678-42-4

Cyanine5 NHS ester chloride

Cyanine5 NHS ester chloride is a red-emitting fluorescent dye designed for the labeling of amino groups in peptides, proteins, and oligonucleotides. This reagent facilitates the detection and visualization of biomolecules in various applications, including fluorescence microscopy and flow cytometry. The reactive NHS ester group ensures efficient conjugation, making it suitable for diverse biochemical research.

Cat. No.

A44924

CAS No.

36536-22-8

1,1',3,3,3',3'-Hexamethylindodicarbocyanine iodide

Synonyms: HIDC

1,1',3,3,3',3'-Hexamethylindodicarbocyanine iodide is a fluorochrome that specifically targets mitochondria in live cells. This carbocyanine dye is utilized for visualizing mitochondrial structures and dynamics in various cell types. Its fluorescent properties make it suitable for applications in cellular imaging and assessments of mitochondrial function.

Cat. No.

A44935

CAS No.

2055138-61-7

Sulfo-Cy5 hydrazide

Sulfo-Cy5 hydrazide is a fluorescent dye characterized by its hydrazide functional group and exhibits excitation and emission wavelengths of 646 nm and 662 nm, respectively. This compound is primarily used in various bioconjugation applications, facilitating the labeling of biomolecules for imaging and detection purposes. Its high fluorescence intensity makes it an essential tool for researchers in the fields of molecular biology and biochemistry.

Cat. No.

A44945

CAS No.

146368-15-2

Cy5-bifunctional dye

Cy5-bifunctional dye is a fluorescent dye characterized by its two NHS ester groups, enabling efficient labeling of primary amines (R-NH2) in proteins, amine-modified oligonucleotides, and other amine-containing molecules. This reagent is essential for applications in bioconjugation and fluorescence imaging, facilitating the study of biomolecular interactions and cellular processes in research settings. The incorporation of Cy5 enhances the detection capabilities in various assays and enables visualization in complex biological samples.

Cat. No.

A44946

CAS No.

1263093-76-0

Cyanine 5 NHS ester tetrafluoroborate

Cyanine 5 NHS ester tetrafluoroborate is a fluorescent dye that targets macromolecules for detection purposes. Exhibiting an excitation wavelength of 638 nm, this compound is suitable for a variety of applications in biological research, including fluorescence microscopy and flow cytometry. Its reactive NHS ester group allows for efficient conjugation to proteins and other biomolecules, facilitating enhanced imaging and analysis in various experimental contexts.

Cat. No.

A44966

CAS No.

2183440-77-7

Cy5.5 bis-NHS ester

Cy5.5 bis-NHS ester is a reactive cyanine dye that utilizes an NHS ester functionality to effectively label amine groups in biomolecules such as peptides, proteins, and oligonucleotides. This fluorescent dye exhibits strong luminescence properties, making it suitable for a variety of applications in biological imaging and diagnostic assays. Its ability to form stable conjugates allows for enhanced visualization in fluorescence microscopy and flow cytometry studies.

Cat. No.

A44969

CAS No.

25470-94-4

Cy3 dimethyl iodide

Cy3 dimethyl iodide is a fluorochrome dye derivative of Cyanine 3 (Cy3), featuring a dimethyl group in the iodide salt form which enhances its aqueous solubility. This near-infrared fluorescent dye is widely utilized in biolabeling and cell imaging applications. Cy3 dimethyl iodide effectively binds to biomolecules, including proteins and antibodies, enabling the visualization and tracking of their localization and dynamic changes within biological samples.

Cat. No.

A44985

CAS No.

1268616-88-1

Cy7 DiAcid

Cy7 DiAcid is a cyanine dye that serves as an effective fluorescent marker for biomolecules, enabling detailed visualization and tracking in various biological applications. This compound can intercalate with double-helical DNA, resulting in enhanced fluorescence upon binding. Its properties make Cy7 DiAcid particularly useful for studies in molecular biology, including nucleic acid labeling and imaging assays.

Cat. No.

A45004

CAS No.

666829-25-0

Cyanine5 carboxylic acid bromide

Synonyms: Cy5 acid bromide

Cyanine5 carboxylic acid bromide is a fluorescent dye that exhibits excitation and emission maxima at 646 nm and 662 nm, respectively. This compound is characterized by a non-reactive carboxylic acid moiety, making it suitable for use in control samples during various biological assays. Its prominent fluorescent properties facilitate applications in imaging and tracking experiments, contributing to advancements in cellular and molecular biology research.

Cat. No.

A45008

CAS No.

162411-29-2

Heptamethine cyanine dye-1

Synonyms: ADS 815EI

Heptamethine cyanine dye-1 is a fluorophore dye characterized by its strong absorption at 858 nm in dichloromethane. This compound is utilized for the synthesis of pH-sensitive near-infrared fluorescent probes, making it valuable for applications in biological imaging and molecular sensing. Its fluorescence properties enable detailed studies of biomolecules in various research contexts.

Cat. No.

A45010

CAS No.

186205-37-8

Cy2 (iodine)

Synonyms: Cyanine2 (iodine)

Cy2 (iodine) is a Cyanine dye known for its utility in fluorescence applications. Featuring a long wavelength, adjustable absorption and emission properties, and high extinction coefficient, Cy2 demonstrates excellent water solubility and straightforward synthesis. This compound is widely employed for the labeling of proteins, antibodies, and small molecules, facilitating advanced research in biochemistry and molecular biology. Its simple mixing reaction enables efficient conjugation to protein antibodies, making it a valuable tool for various labeling and imaging studies.

Cat. No.

A45019

CAS No.

228272-69-3

Cy3B

Cy3B is an advanced variant of the fluorescent dye Cy3 (Cyanine3) known for its enhanced spectral properties. This dye emits fluorescence within the green to orange wavelength range, making it suitable for applications in fluorescence microscopy and flow cytometry. Cy3B is particularly useful for tagging biomolecules in various biological systems, allowing for the study of molecular interactions and dynamics.

Cat. No.

A45026

CAS No.

1656990-68-9

Sulfo-Cy3 maleimide potassium

Sulfo-Cy3 maleimide potassium is a fluorescent dye that features a maleimide group linked by a short alkyl chain. This reagent is primarily employed for the specific labeling of antibodies and sensitive proteins, enabling enhanced visualization in various biological assays. Its strong fluorescent properties facilitate applications in immunofluorescence and other microscopy techniques, making it a valuable tool for researchers in chemical biology and protein analysis.