Metal Ion Indicators

Cat. No.

A24517

CAS No.

874748-20-6

Coppersensor 1

Coppersensor-1 (CS1) is a membrane-permeable fluorescent probe with picomolar affinity for Cu⁺ ions, exhibiting high selectivity over other cellular metal ions. It enables sensitive and selective detection of copper(I) in biological samples, including live cells. CS1 is suitable for imaging studies related to copper homeostasis in diseases such as cancer, cardiovascular disorders, and neurodegenerative conditions.

Cat. No.

A24536

CAS No.

1447815-38-4

RhoNox-1

RhoNox-1 is a fluorescent probe designed for the specific detection of divalent iron ions (Fe²⁺). Upon reaction with Fe²⁺, RhoNox-1 forms an irreversible orange-red fluorescent product (Ex/Em: 540/575 nm). It efficiently penetrates cell membranes and is suitable for detecting intracellular Fe²⁺, with a tendency to localize in the Golgi apparatus.

Cat. No.

A24615

CAS No.

109628-27-5

TSQ

TSQ is a membrane-permeable fluorescent probe designed for the detection of zinc ions within cells, specifically targeting the cytosolic compartment. It exhibits a fluorescence emission maximum at approximately 495 nm when excited at 334 nm, enabling effective intracellular imaging of zinc-containing proteins. TSQ forms a complex with Zn2+ in the presence of Ca2+ and Mg2+, resulting in a distinctive blue fluorescence signal, making it a valuable tool for research applications involving cellular zinc dynamics and metalloprotein studies.

Cat. No.

A24770

CAS No.

288574-78-7

Zinpyr-1

Zinpyr-1 is a zinc-responsive fluorescent indicator designed for the detection of biologically mobile zinc ions. This compound exhibits a shift in excitation from 515 to 507 nm as zinc concentrations increase, enabling sensitive quantification of zinc levels. Zinpyr-1 is valuable for investigating zinc's role in various biological processes and can be utilized in live cell imaging and other fluorescence-based assays.

Cat. No.

A24928

CAS No.

181530-09-6

Zinquin ethyl ester

Zinquin ethyl ester is a zinc ion fluorophore specifically designed for the detection of intracellular zinc ions. This lipophilic probe readily penetrates cell membranes and exhibits a strong affinity for Zn2+, resulting in blue fluorescence upon binding. Primarily utilized in research applications focused on zinc signaling and cellular metal ion dynamics, Zinquin ethyl ester serves as a valuable tool for studying zinc-related biological processes.

Cat. No.

A24940

CAS No.

129423-53-6

SBFI-AM

Synonyms: Sodium-binding Benzofuran Isophthalate Acetoxymethyl ester

SBFI-AM is a sodium-selective fluorescent indicator designed for monitoring Na+ concentrations in biological systems. With a Kd of 6.7 mM for Na+ and 166 mM for K+, SBFI-AM demonstrates high selectivity for sodium ions. Its excitation and emission wavelengths are 340/380 nm and 500 nm, respectively. This reagent is widely used in cellular imaging and physiological studies to investigate sodium signaling and ion homeostasis.

Cat. No.

A25030

CAS No.

852057-94-4

KMG-104

KMG-104 is a cell-impermeant fluorescent probe specifically designed for the selective detection of Mg2+ ions. This reagent enables real-time imaging of Mg2+ mobilization in the cytoplasm across various cell types, making it a valuable tool for studies involving cellular signaling and ion homeostasis. Its high specificity and sensitivity facilitate the exploration of magnesium's role in physiological and pathological processes.

Cat. No.

A43705

CAS No.

3047612-66-5

Cobalt(II) ions probe 1

Cobalt(II) ions probe 1 is a selective fluorescent sensor for detecting Co2+ in biological environments. This probative compound effectively binds to cobalt ions, exhibiting fluorescence at 380 nm, even in the presence of other metal ions. It is particularly useful for applications in cobalt ion imaging and tracking within cellular and biochemical systems.

Cat. No.

A43731

CAS No.

443302-08-7

ZnAF-1F

ZnAF-1F is a selective fluorophore that targets zinc ions (Zn2+) with a dissociation constant (Kd) of 2.2 nM. This compound is suitable for use as a fluorescent probe in cellular environments, allowing for the visualization and quantification of Zn2+ ions. ZnAF-1F exhibits an excitation wavelength of 489 nm and an emission wavelength of 514 nm, facilitating sensitive and accurate imaging in various biological applications.

Cat. No.

A43732

CAS No.

1945-77-3

Methylthymol blue tetrasodium

Methylthymol blue tetrasodium is a metallochromic indicator that effectively binds metal ions, resulting in distinct color changes. It serves as a sensitive tool for determining the presence of sulfate and calcium in various samples. This reagent is widely utilized in analytical chemistry and environmental testing for its reliable performance in metal detection and quantification.

Cat. No.

A43761

CAS No.

866534-64-7

CTAP-1

CTAP-1 is a monovalent copper ion probe that selectively binds to Cu(I), effectively inhibiting photoinduced electron transfer and enhancing fluorescence emission. This reagent provides copper-dependent perinuclear staining that colocalizes with mitochondria and the Golgi apparatus. CTAP-1 is ideally suited for imaging intracellular pools of Cu(I), facilitating studies in cellular copper homeostasis and related biological processes.

Cat. No.

A43769

CAS No.

1084800-67-8

ZP1BG

ZP1BG is a fluorescent probe designed for the specific detection of Zn2+ ions, formed through the covalent attachment of the zinc sensor ZP1 from the Zinpyr family to a benzyl guanine moiety. This reagent allows for the imaging and quantification of Zn2+ concentrations within neuronal organelles, including the Golgi apparatus and mitochondria. Its application is valuable for studies focused on zinc's role in cellular signaling and neurobiology.

Cat. No.

A43888

CAS No.

181530-16-5

Zinquin AM ester

Zinquin AM ester is a fluorescent dye that serves as a specific sensor for assessing cellular zinc (Zn2+) levels. Its AM ester modification enhances membrane permeability, allowing for effective intracellular staining and visualization of zinc dynamics in live cells. This reagent is widely utilized in studies investigating zinc's role in various biological processes and cellular signaling pathways.

Cat. No.

A44723

CAS No.

1816254-69-9

DA ZP1

DA ZP1 is a highly sensitive fluorogenic zinc(II) sensor with a dissociation constant (Kd) of 0.6 nM for Zn2+. It exhibits fluorescence with excitation and emission wavelengths at 490 nm and 522 nm, respectively. This compound is primarily used in biological research to detect and quantify zinc ions in various cellular and biochemical systems, facilitating studies on zinc's role in physiological and pathological processes.

Cat. No.

A44733

CAS No.

3682-47-1

Fast Sulphon Black F

Fast Sulphon Black F is a selective copper indicator that facilitates the detection and quantification of copper ions in various solutions. This reagent is particularly useful in EDTA titration, providing clear and reliable results for analytical procedures in chemical research. Its specificity for copper makes it an essential tool for studies involving metal ion interactions and assessments in environmental and industrial applications.

Cat. No.

A44794

CAS No.

234075-45-7

Phen Green SK diacetate (5/6-mixture)

Synonyms: PGSK diacetate (5/6-mixture)

Phen Green SK diacetate (5/6-mixture) is a metal ion-sensitive fluorescent probe designed to penetrate cell membranes for effective intracellular analysis. This reagent selectively chelates metal ions such as Fe2+, Cd2+, Co2+, Ni2+, and Zn2+, leading to fluorescence quenching, which can be reversed by the addition of a membrane-permeable chelator. The probe's excitation and emission maxima are at 507 nm and 532 nm, respectively, making it a valuable tool for studying cellular iron dynamics and the intracellular chelatable iron pool in various biological research applications.

Cat. No.

A44876

CAS No.

1479071-34-5

GSHtracer

GSHtracer is a ratiometric probe designed for the quantification of glutathione (GSH) levels within cellular environments. Upon binding to GSH, GSHtracer exhibits a shift in fluorescence with excitation/emission wavelengths from 520/580 nm to 430/510 nm. This dynamic change enables precise detection and monitoring of GSH concentrations, making it a valuable tool in oxidative stress research and cellular metabolism studies.

Cat. No.

A45249

CAS No.

1787-61-7

Eriochrome black T, Indicator

Eriochrome Black T is a metal ion indicator primarily targeting Ca2+ and Mg2+ ions. This complexing agent is widely utilized in complexometric titrations, where it forms colored complexes with metal ions, signaling the endpoint through a noticeable color change. Additionally, Eriochrome Black T serves as an anionic azo dye in photocatalytic degradation studies, allowing for the assessment of photocatalyst efficiency. In loop-mediated isothermal amplification (LAMP), the dye's color transitions from purple to sky blue upon the consumption of Mg2+, indicating a positive reaction, with an optimal concentration of 60 μM for effective detection of Mycobacterium tuberculosis at a sensitivity of 1 pg DNA per reaction.

Cat. No.

A45799

CAS No.

100743-65-5

3,5-DiBr-PAESA

3,5-DiBr-PAESA is a water-soluble pyridylazo chromogenic reagent designed for the sensitive detection of silver ions. It functions by masking copper ions with EDTA and dissociating silver chelates using bromide ions, allowing for precise quantification of silver at sub-milligram levels in strongly acidic high-copper environments. This reagent is particularly useful in flow injection spectrophotometry applications for environmental and analytical chemistry research.

Cat. No.

A45800

CAS No.

81608-06-2

5-Br-PAPS

5-Br-PAPS is a specific zinc (Zn2+) metallochromic indicator that exhibits distinctive colorimetric properties upon binding to free Zn2+. This reagent is utilized in assays designed to measure free zinc ions in biological samples, forming a strongly colored red complex that enhances detection sensitivity. Its application is essential for studies assessing zinc's role in various biological processes and disease states.

Cat. No.

A73489

CAS No.

65602-55-3

Marionol

Marionol is a flavonol compound that serves as a highly selective fluorescence probe for copper ions (Cu²⁺). Featuring intramolecular proton transfer in its excited state (ESIPT), Marionol produces strong fluorescence when excited by ultraviolet light, with a maximum excitation wavelength of 350 nm and emission around 510 nm, depending on the solvent used. This compound is valuable for applications in metal ion detection and environmental monitoring, facilitating research in biochemistry and analytical chemistry.

Cat. No.

A87366

CAS No.

54010-75-2

Zinc trifluoromethanesulfonate

Synonyms: Zinc(II) Triflate

Zinc trifluoromethanesulfonate (Zinc (II) Triflate) is a Zn(II) salt that plays a crucial role in potentiometric titration for determining the stability constants of Zn(II)-quinoline sulfonamide complexes. Its aqueous solutions can form micellar structures, impacting the desolvation kinetics of Zn(II) and promoting dendrite growth on zinc anodes. This behavior can limit the long-term cycling efficiency of zinc-based anodes, making it a relevant compound for research in electrochemistry and battery development.

Cat. No.

A87435

CAS No.

3051-09-0

Murexide

Synonyms: Ammonium purpurate

Murexide, also known as ammonium purpurate, acts as a colorimetric indicator in complexometric titrations, particularly for the assessment of water hardness. Its ability to form stable complexes with metal ions makes it an essential reagent in analytical chemistry. Murexide is widely employed in laboratories for its effective and accurate detection of calcium and magnesium ions in various samples.

Cat. No.

A88133

CAS No.

569-58-4

Aluminon

Synonyms: ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium

Aluminon (Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium) serves as a complexometric titration indicator, facilitating accurate determination of metal ion concentrations. Additionally, it exhibits properties as a nuclease inhibitor, making it beneficial in transfection studies. This compound is widely utilized in various life science research applications for its reliable performance in both analytical and molecular biology contexts.

Cat. No.

A89333

CAS No.

3270-25-5

Acid chrome blue K

Acid Chrome Blue K serves as a metal indicator primarily targeting magnesium ions (Mg2+). In applications such as Loop-mediated Isothermal Amplification (LAMP), the color of the solution transitions from red to blue, correlating with a decrease in Mg2+ concentration. This property makes Acid Chrome Blue K a valuable reagent for monitoring ion levels in various biochemical assays and enhancing the sensitivity of nucleic acid amplification techniques.