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Verteporfin

Catalog No. A12658
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YAP inhibitor

Verteporfin is a small molecule that inhibits TEAD–YAP association and YAP-induced liver overgrowth. It is also a potent second-generation photosensitizing agent derived from porphyrin. Learn More

Product Citations (3)

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- Po-Ju Lee, .et al. Epstein-Barr viral product-containing exosomes promote fibrosis and nasopharyngeal carcinoma progression through activation of YAP1/FAPα signaling in fibroblasts, J Exp Clin Cancer Res, 2022, Aug 20;41(1):254 PMID: 35986369
- Wang Y, .et al. Verteporfin inhibits lipopolysaccharide-induced inflammation by multiple functions in RAW 264.7 cells, Toxicol Appl Pharmacol, 2019, 2019 Dec 5;387:114852 PMID: 31812773
- Abe T, .et al. Role of YAP Activation in Nuclear Receptor CAR-Mediated Proliferation of Mouse Hepatocytes, Toxicol Sci, 2018, Oct 1;165(2):408-419 PMID: 29893953
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XMU-MP-1

Catalog No. A16228
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MST1/MST2 inhibitor

XMU-MP-1 is a reversible and selective MST1/2 inhibitor with IC50 values of 71.1±12.9 nM and 38.1 ± 6.9 nM against MST1 and MST2, respectively. Learn More

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