Antifection

Cefixime is a third generation cephalosporin antibiotic that is orally active.

Rolitetracycline is a tetracycline antibiotic.

GSK1265744 (GSK744) is a potential inhibitor of HIV integrase with IC50 value of 3 nM

Ecabet sodium is a widely employed mucoprotective agent for the treatment of gastric ulcers.

Solithromycin is a novel ketolide antibiotic. Solithromycin (CAS 760981-83-7) can be used for anti-infection, and It is expected to be the first macrolide antibiotic available in intravenous, oral, and pediatric suspension formulations in over 20 years.

Squalamine(MSI-1256) is an aminosterol compound with potent broad spectrum antiviral activity.

Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively.

BMS-626529 is a potent HIV-1 attachment inhibitor. BMS-663068 is also the phosphonooxymethyl prodrug of BMS-626529 that targets HIV-1 gp120 and prevents its binding to CD4(+) T cells.

Erythromycin Cyclocarbonate, derivative of Erythromycin, inhibits protein synthesis of bacteria by binding to the 50S ribosome.

Mefloquine HCl is a blood schizonticide by inhibiting hemozoin formation.

Micafungin Sodium is an inhibitor of 1, 3-beta-D-glucan synthesis.

Demeclocycline HCl is a tetracycline antibiotic via inhibition of protein synthesis by bacteria

Nelfinavir Mesylate is a potent HIV protease inhibitor with Ki of 2 nM.

Aminoacyl tRNA synthetase-IN-1, is a bacterial aminoacyl tRNA synthetase (aaRS) inhibitor.

Vibunazole is an antifungal agent.

KIN-1148, a small-molecule IRF3 agonist, functions as an influenza vaccine adjuvant by modulating the antiviral immune response.

GSK3532795, also known as BMS-955176, is a potent, orally active, second-generation HIV-1 maturation inhibitor. CAS: 1392312-45-6 (free base) 2023808-13-9 (HCl) 2023798-97-0 (HCl hydrate) 2097784-79-5 (oxalate)

Cinchonine prevents High-Fat-Diet-Induced Obesity through downregulation of Adipogenesis and Adipose inflammation.

Cefadroxil, also known as Duricef, is an antibiotic effective against pyodermic skin diseases, such as Staphylococcus aureus and Streptococcus pyogenes.

Cefamandole nafate is a pro-drug that is hydrolyzed by plasma esterases to produce cefamandole, second-generation cephalosporin antibiotic with bactericidal activity. Cefamandole nafate is used to study the effects of expression and inhibition of PBP 2A and other penicillin-binding proteins (PDPs) on bacterial cell wall mucopeptide synthesis. Cefamandole binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Turimycin is a macrolide antibiotic that is effective against a wide spectrum of pathogens.

Cefepime Dihydrochloride Monohydrate is a broad-spectrum cephalosporin with enhanced coverage against Gram-positive and Gram-negative bacteria.

Cefsulodin sodium salt hydrate is a third generation β lactam antibiotic and member of the cephems subgroub of antibiotics.

Cefonicid sodium is a broadspectrum cephalosporin antibiotic which inhibits the formation of the bacterial cell wall.

Chlorobutanol (trichloro-2-methyl-2-propanol) is a preservative, sedative, hypnotic and weak local anesthetic similar in nature to chloral hydrate.

Sulfachlorpyridazine, also known as Sonilyn, Cluricol, Durasulf, and Ba 10370, is an antibacterial agent typically used in agricultural practices.

Benznidazol (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease.

Pyrogallol is a polyphenol compound, which has anti-fungal and anti-psoriatic properties. Pyrogallol is a reductant that is able to generate free radicals, in particular superoxide anions.

Procaine hydrochloride is a local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block.

Piromidic acid is antibacterial against mainly gram negative organisms. It is used for urinary tract and intestinal infections.

Cinoxacin was an older synthetic antimicrobial related to the quinolone class of antibiotics with activity similar to oxolinic acid and nalidixic acid.

Phthalylsulfacetamide is an antibiotic sulfonamide used as a leprostatic agent to treat urinary tract infections.

Cephapirin Sodium is the sodium salt form of cephapirin, a semi-synthetic, broad-spectrum, first-generation cephalosporin antibiotic. It is beta-lactam with bactericidal activity. Cephalosporin antibiotic is effective against gram-negative and gram-positive organisms. Cephapirin sodium inhibits bacterial cell wall synthesis by inhibiting the final transpeptidation step of peptidoglycan synthesis and subsequent cross-linking of peptidoglycan units.

Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. It is only functional against Gram-positive bacteria, It penetrates into human lung tissue.

Benzyl isothiocyanate is a member of natural isothiocyanates with antimicrobial activity. Benzyl isothiocyanate potent inhibits cell mobility, migration and invasion nature and matrix metalloproteinase-2 (MMP-2) activity of murine melanoma cells.

Cefuroxime axetil is a second generation cephalosporin antibiotic with a broad spectrum activity against Gram positive and Gram negative bacteria.

Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations.

Meropenem trihydrate (SM 7338 trihydrate) is a carbapenem antibiotic with broad-spectrum antibacterial activity.

Faropenem sodium is an orally bioavailable penem antibiotic which can efficiently kill Mycobacterium tuberculosis.

Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.

Nicarbazin is an equimolar complex of 4,4'-Dinitrocarbanilide and 2-Hydroxy-4,6-dimethylpyrimidine. It is used as a coccidiostat for poultry.

Sulfamethoxazole sodium is an antibiotic used for bacterial infections.

Cefodizime sodium is a third generation cephalosporin antibiotic with a broad spectrum of antibacterial activity.

Cefazedone is a semisynthetic first-generation cephalosporin with antibacterial activity.

Cephapirin Benzathine is the benzathine salt form of cephapirin. Cephapirin Benzathine is the first generation cephalosporin with broad spectrum antibiotic activity.

Taurolidine is a broad-spectrum antimicrobial for the prevention of central venous catheter-related infections. Taurolidine has a direct and selective antineoplastic effect on brain tumor cells by the induction of apoptosis.

Sorbic acid is a mold and yeast inhibitor. Used as a fungistatic agent for foods, especially cheeses.

Cefotetan Hydrochloride is a second-generation cephalosporin that is active against some strains of β-lactamase producing bacteria. It shows anti-microbial activity against Gram-positive and Gram-negative bacteria; it is more efficacious against Gram-negative and anaerobic bacteria

Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.

Phenazine methylsulfate is a free radical generator. Phenazine methylsulfate has been used as an electron transfer reactant in cell viability assays.