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Neuropeptide S Receptor

Neuropeptide S receptor (NPSR) ligands are research compounds for a neuronal G protein-coupled receptor. Receptor signaling is associated with intracellular second messengers and is studied in arousal, stress responses and neural circuit function. ML154 is listed as an antagonist, while R06039-691 and R06039-641 are annotated as agonists. The category also includes other receptor-related modulators. Differences in the listed functional classes provide context for selecting compounds when examining receptor pharmacology and downstream signaling in experimental systems.

4 Items

  • R06039-691
    Cat. No.
    A62177
    CAS No.
    2138445-51-7

    R06039-691

    R06039-691 is an agonist of the neuropeptide S receptor (NPSR), exhibiting an EC50 of 93 nM. This compound is involved in the modulation of several biological functions, including arousal, stress and anxiety responses, memory processes, and food intake, through the activation of NPSR. Its ability to influence these physiological pathways makes R06039-691 a valuable tool for research in neurobiology and potential therapeutic applications in anxiety and related disorders.

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  • R06039-641
    Cat. No.
    A62178
    CAS No.
    2138444-75-2

    R06039-641

    R06039-641 is a potent neuropeptide S receptor (NPSR) agonist with an EC50 value of 169 nM. By activating NPSR, R06039-641 modulates various physiological processes, including arousal, stress and anxiety responses, memory formation, and appetite regulation. This compound is valuable for research focused on neurobiology and behavioral sciences.

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  • R06039-693
    Cat. No.
    A62179
    CAS No.
    2138295-88-0

    R06039-693

    R06039-693 is a neuropeptide S receptor (NPSR) agonist, exhibiting an EC50 value of 169 nM. By activating NPSR, R06039-693 plays a pivotal role in modulating several biological functions, including arousal, stress and anxiety responses, memory processes, and food intake regulation. This compound is valuable for researchers investigating neuropeptide signaling pathways and their implications in neurobiology and behavioral science.

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  • R06039-696
    Cat. No.
    A62181
    CAS No.
    2138295-90-4

    R06039-696

    R06039-696 is a selective agonist of the neuropeptide S receptor (NPSR) with an EC50 of 91 nM. This compound plays a significant role in modulating various biological functions, including arousal, stress and anxiety responses, memory processes, and appetite regulation. R06039-696 is valuable for research applications focused on neurobiology and stress-related disorders.

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