Catalog No.
Product Name
Application
Product Information
Citations
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Ligand for E3 Ligase
CRBN ligand-869 is a ligand for the E3 ubiquitin ligase cereblon (CRBN) that facilitates the recruitment of this protein for targeted protein degradation. This compound can be conjugated with a ligand specific to the target protein through a suitable linker to create a PROTAC (proteolysis-targeting chimera). CRBN ligand-869 is valuable for research applications in protein modulation and therapeutic discovery. -
Ligand for E3 Ligase
CRBN ligand-508 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be conjugated to a target protein ligand through a linker, enabling the development of proteolysis-targeting chimeras (PROTACs). It is utilized in research applications involving targeted protein degradation and E3 ligase modulation. -
Ligand for E3 Ligase
CRBN ligand-426 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a linker to create a proteolysis-targeting chimeric molecule (PROTAC). It is useful in studies related to targeted protein degradation and the modulation of cellular protein levels. -
Ligand for E3 Ligase
CRBN ligand-314 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN for targeted protein degradation. This compound can be combined with a target protein ligand through a linker to create a PROTAC (proteolysis-targeting chimera), a valuable tool in the study of protein function and turnover in cellular processes. Its applications include research on targeted therapy and novel drug development strategies in oncology and other disease areas. -
Ligand for E3 Ligase
CRBN ligand-429 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein for targeted protein degradation applications. This compound can be effectively conjugated to a target protein ligand using a linker, enabling the formation of PROTAC (proteolysis-targeting chimeras) molecules. It serves as a valuable tool in the study of targeted degradation pathways and has potential utility in therapeutic research focused on modulating protein levels within cellular systems. -
Ligands for E3 Ligase
CRBN ligand-164 is a selective ligand for the CRBN E3 ubiquitin ligase, facilitating the ubiquitination of target proteins. This compound is instrumental in the development of PROTACs (proteolysis-targeting chimeras), which harness the ubiquitin-proteasome system to selectively degrade proteins of interest. Its ability to induce targeted protein degradation makes CRBN ligand-164 valuable in drug discovery and therapeutic research. -
Ligand for E3 Ligase
CRBN ligand-221 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein in protein degradation pathways. This compound can be conjugated to a target protein ligand through a linker, allowing for the development of proteolysis targeting chimeras (PROTACs). Its applications include targeted protein degradation studies and the exploration of novel therapeutic strategies in various diseases. -
Ligand for E3 Ligase
CRBN ligand-750 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound serves as a valuable tool for the development of PROTACs (Proteolysis Targeting Chimeras) by enabling the targeted degradation of specific proteins through ubiquitin-mediated pathways. Its application in chemical biology underscores its potential in elucidating protein function and developing innovative therapeutic strategies. -
Ligand for E3 Ligase
CRBN ligand-207 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN in protein degradation pathways. This compound serves as a crucial element for developing PROTACs (Proteolysis Targeting Chimeras) by linking to target protein ligands through a suitable linker. Its ability to promote targeted protein degradation makes it a valuable tool in cellular and molecular biology research, particularly in studies focused on ubiquitin-mediated proteolysis and the modulation of protein homeostasis. -
Ligand for E3 Ligase
CRBN ligand-341 is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be conjugated to a target protein ligand through a linker to create a PROTAC (proteolysis-targeting chimera), enabling targeted protein degradation. Its utilization aids in studying protein homeostasis and the modulation of cellular functions in various research applications. -
Ligand for E3 Ligase
CRBN ligand-885 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to target protein ligands through a linker to create proteolysis-targeting chimeras (PROTACs), enabling targeted protein degradation. Its application is crucial in the study of protein homeostasis and the modulation of various cellular pathways. -
Ligand for E3 Ligase
CRBN ligand-230 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN in targeted protein degradation applications. This compound can be conjugated to target protein ligands via a linker, thereby enabling the formation of PROTACs (Proteolysis Targeting Chimeras). CRBN ligand-230 is instrumental in research focused on ubiquitination processes and therapeutic strategies for targeted protein modulation. -
Ligand for E3 Ligase
CRBN ligand-559 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), designed to facilitate the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a linker, enabling the formation of a PROTAC (proteolysis-targeting chimera). It is valuable for research applications focused on targeted protein degradation pathways and the exploration of E3 ligase-mediated ubiquitination processes. -
Ligand for E3 Ligase
CRBN ligand-203 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be conjugated to a target protein ligand through a linker, enabling the formation of a PROTAC (Proteolysis Targeting Chimera). It serves a critical role in targeted protein degradation studies and is useful for research into therapeutic applications involving the modulation of protein levels within cells. -
Ligand for E3 Ligase
CRBN ligand-355 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be conjugated to specific target protein ligands through a linker to create PROTACs (Proteolysis Targeting Chimeras), enabling targeted protein degradation. It serves as a valuable tool for researchers investigating protein dynamics, ubiquitination pathways, and therapeutic strategies in cancer and other diseases. -
Ligand for E3 Ligase
CRBN ligand-335 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be utilized in the construction of PROTACs by linking it to other target protein ligands via a suitable linker. Its application supports the study of targeted protein degradation and the modulation of protein levels in various biological contexts. -
Ligand for E3 Ligase
CRBN ligand-561 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be utilized to assemble a PROTAC (Proteolysis Targeting Chimera) by linking it to a target protein ligand through a suitable linker. Research applications include targeted protein degradation and investigations into proteostasis mechanisms, offering insights into therapeutic strategies for various diseases. -
Ligand for E3 Ligase
CRBN ligand-411 is a small molecule ligand that targets the E3 ubiquitin ligase cereblon (CRBN), facilitating its recruitment to specific protein substrates. This compound can be utilized in the development of proteolysis targeting chimeras (PROTACs) by linking to a target protein ligand through a suitable linker. CRBN ligand-411 supports research in targeted protein degradation, enabling the investigation of cellular processes and therapeutic applications in various diseases. -
Ligand for E3 Ligase
CRBN ligand-699 is a small molecule ligand for the E3 ubiquitin ligase cereblon (CRBN). It facilitates the recruitment of the CRBN protein, enabling targeted degradation of specific proteins when linked to a target protein ligand through a suitable linker. This compound is instrumental in the development of PROTACs (proteolysis-targeting chimeras) for research applications focused on ubiquitin-mediated protein turnover and targeted therapy strategies. -
Ligand for E3 Ligase
CRBN ligand-755 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), functioning to selectively recruit the CRBN protein. This compound is designed for use in PROTAC (protasome-targeting chimeras) development, allowing for targeted protein degradation in cellular studies. Its ability to link to a target protein ligand via a linker opens avenues for manipulating protein levels in various biological research applications. -
Ligands for E3 Ligase
CRBN ligand-162 is a ligand for the CRBN-type E3 ubiquitin ligase, facilitating the targeted degradation of proteins through the ubiquitin-proteasome system. This compound is utilized in the design and synthesis of PROTACs (Proteolysis Targeting Chimeras), which are powerful tools for selective protein degradation in various biological research applications. Its utilization promotes advancements in understanding protein function and therapeutic interventions in diseases linked to protein dysregulation. -
Ligand for E3 Ligase
CRBN ligand-636 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound can be utilized in the design of PROTACs (Proteolysis Targeting Chimeras) by linking it to a target protein ligand through a linker, enabling targeted ubiquitination and degradation of the desired protein. CRBN ligand-636 is valuable in research applications aimed at exploring protein function, degradation pathways, and therapeutic interventions in various diseases. -
Ligand for E3 Ligase
CRBN ligand-571 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound can be utilized to synthesize PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. Its distinctive mechanism of action makes it a valuable tool for probing protein degradation pathways and studying the dynamics of protein homeostasis in cellular systems. -
Ligand for E3 Ligase
CRBN ligand-616 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This reagent can be conjugated with a target protein ligand through a linker to generate a proteolysis-targeting chimeric molecule (PROTAC). It supports research in targeted protein degradation, offering potential applications in therapeutic development and cellular signaling studies. -
Ligand for E3 Ligase
CRBN ligand-631 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound is instrumental in the design of PROTACs (Proteolysis Targeting Chimeras) by allowing the conjugation of a target protein ligand through a suitable linker. Its ability to modulate protein degradation pathways makes it valuable for research into targeted protein degradation and therapeutic applications. -
Ligand for E3 Ligase
CRBN ligand-209 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the targeted recruitment of the CRBN protein. This compound can be conjugated to a specific target protein ligand through a linker, enabling the formation of PROTACs (proteolysis-targeting chimeras). It is valuable for research applications focused on targeted protein degradation and exploring protein turnover mechanisms within cellular systems. -
Ligand for E3 Ligase
CRBN ligand-418 is a novel ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound is designed to facilitate the recruitment of CRBN to target proteins when conjugated via a linker, thereby enabling the formation of Proteolysis Targeting Chimeras (PROTACs). Its application in targeted protein degradation offers significant potential in therapeutic research and development. -
Ligand for E3 Ligase
CRBN ligand-695 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this protein in targeted protein degradation applications. It can be conjugated with a target protein ligand through a linker to create a PROTAC, enabling the selective degradation of specific proteins. This compound is valuable for research focused on targeted therapeutics and the manipulation of cellular protein levels. -
Ligand for E3 Ligase
CRBN ligand-687 is a small molecule ligand that targets the E3 ubiquitin ligase cereblon (CRBN). It is designed to facilitate the recruitment of cereblon to specific target proteins, enabling the formation of PROTACs (Proteolysis Targeting Chimeras). This compound is valuable for studies related to targeted protein degradation and offers potential applications in therapeutic development. -
Ligand for E3 Ligase
CRBN ligand-614 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand via a linker, enabling the formation of a proteolysis-targeting chimeric molecule (PROTAC). CRBN ligand-614 is valuable for research applications in targeted protein degradation and the study of ubiquitin-proteasome pathway mechanisms. -
Ligand for E3 Ligase
CRBN ligand-354 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be utilized in targeted protein degradation approaches, such as the development of PROTACs, by linking it to a target protein ligand through a suitable linker. Its role in protein homeostasis and degradation pathways makes it valuable for studying therapeutic mechanisms in various biological contexts. -
Ligand for E3 Ligase
CRBN ligand-437 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN) that facilitates the assembly of CRBN with target proteins. This compound can be utilized in the design of PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. Research applications include studies on protein degradation pathways and the development of targeted protein degradation strategies for therapeutic purposes. -
Ligand for E3 Ligase
CRBN ligand-889 is a ligand for the E3 ubiquitin ligase cereblon (CRBN) that facilitates the recruitment of CRBN to target proteins. This compound can be conjugated with a target protein ligand through a linker, allowing the formation of a PROTAC (proteolysis-targeting chimera). CRBN ligand-889 is instrumental in studying protein degradation pathways and the development of targeted therapies leveraging the ubiquitin-proteasome system. -
Ligand for E3 Ligase
CRBN ligand-250 is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein in targeted protein degradation applications. This compound can be conjugated to target protein ligands through a linker to create a PROTAC (proteolysis-targeting chimera), allowing for the selective degradation of substrate proteins. Its utility in research encompasses the study of protein homeostasis and therapeutic interventions in various diseases. -
Ligand for E3 Ligase
CRBN ligand-380 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of cereblon, enabling the targeted degradation of specific proteins through the formation of PROTACs (Proteolysis Targeting Chimeras). CRBN ligand-380 is instrumental in research applications aimed at exploring targeted protein degradation and ubiquitin-mediated proteolysis. -
Ligand for E3 Ligase
CRBN ligand-408 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound is pivotal for the development of proteolysis-targeting chimeras (PROTACs) by linking target protein ligands through a suitable linker. It is useful in studying the modulation of protein degradation pathways and exploring the therapeutic potential of targeted protein degradation. -
Ligand for E3 Ligase
Thalidomide-5-F-6-I is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to target protein ligands through a linker, enabling the development of PROTACs for targeted protein degradation. Its applications include drug discovery and the investigation of protein regulation mechanisms. -
Ligand for E3 Ligase
CRBN ligand-698 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be utilized in the construction of PROTACs (proteolysis-targeting chimeras) by linking to a target protein ligand through a suitable linker. It is valuable in studies of targeted protein degradation and offers potential applications in drug discovery and development. -
Ligand for E3 Ligase
4-Br-7-O-Desamino lenalidomide is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein within cellular pathways. This compound can be conjugated to a target protein ligand through a linker to create a proteolysis-targeting chimera (PROTAC). Its application in biotherapeutic research underscores its potential in targeted protein degradation strategies, providing insights into the modulation of protein levels in various biological contexts. -
Ligand for E3 Ligase
CRBN ligand-712 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this essential protein. By utilizing CRBN ligand-712, researchers can effectively create PROTACs (Proteolysis Targeting Chimeras) by linking it to target protein ligands through a suitable linker. This compound is instrumental in studies focused on targeted protein degradation and the modulation of protein levels within cells, providing valuable insights into cellular processes and therapeutic applications. -
Ligand for E3 Ligase
CRBN ligand-740 is a small molecule ligand that targets the E3 ubiquitin ligase cereblon (CRBN). It facilitates the recruitment of CRBN, enabling the formation of targeted protein degraders, or PROTACs, through conjugation with specific target protein ligands via a linker. This compound is valuable in the study of protein degradation pathways and offers a tool for research applications in therapeutic development focused on targeted protein modulation. -
Ligand for E3 Ligase
CRBN ligand-641 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), known for its role in targeted protein degradation. This compound facilitates the recruitment of CRBN to target proteins when conjugated with a suitable ligand through a linker, enabling the development of PROTACs. Its applications span drug discovery and therapeutic development, particularly in cancer research and the modulation of protein levels within cellular pathways. -
Ligand for E3 Ligase
CRBN ligand-481 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound effectively recruits CRBN, facilitating the degradation of target proteins through the mechanism of proteolysis-targeting chimeras (PROTACs). Its application in research includes the development of novel therapeutic strategies targeting specific proteins for degradation, making it a valuable tool for studies in protein regulation and cellular homeostasis. -
Ligand for E3 Ligase
CRBN ligand-487 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. It can be utilized in the design of PROTACs (proteolysis-targeting chimeras) by linking to a target protein ligand via a suitable linker. This compound is valuable in studies focused on targeted protein degradation and the modulation of cellular pathways through ubiquitination. -
Ligand for E3 Ligase
CRBN Ligand-539 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. It serves as a crucial component in the development of proteolysis-targeting chimeras (PROTACs) by enabling the conjugation of target protein ligands through a linker. This functionality allows researchers to selectively degrade proteins of interest, providing valuable insights into protein regulation and cellular pathways. -
Ligand for E3 Ligase
CRBN ligand-558 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated with a target protein ligand through a linker to create a PROTAC, which can be utilized in targeted protein degradation research and therapeutic development. Its ability to modulate protein levels by facilitating ubiquitination makes it a valuable tool in cellular and molecular biology studies. -
Ligand for E3 Ligase
CRBN ligand-716 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be utilized in the development of proteolysis-targeting chimeras (PROTACs) by linking it to a target protein ligand via a suitable linker. Its primary application includes targeted protein degradation, contributing valuable insights into protein regulation and therapeutic interventions. -
Ligand for E3 Ligase
CRBN ligand-494 is a ligand for the E3 ubiquitin ligase cereblon (CRBN) that facilitates the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a linker, enabling the formation of a PROTAC (proteolysis targeting chimera). Its application in targeted protein degradation research makes it a valuable tool for studying protein regulation and therapeutic interventions in cellular pathways. -
Ligand for E3 Ligase
CRBN ligand-583 is a small molecule ligand that targets the E3 ubiquitin ligase cereblon (CRBN). It is designed to facilitate the recruitment of CRBN to specific target proteins. By being conjugated to a target protein ligand through a linker, CRBN ligand-583 can be utilized in the development of PROTACs (Proteolysis-targeting chimeras) for targeted protein degradation studies and therapeutic applications in cancer and other diseases. -
Ligand for E3 Ligase
CRBN ligand-727 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), serving to selectively recruit the cereblon protein. This compound can be conjugated to a target-specific protein ligand through a linker, facilitating the creation of a proteolysis-targeting chimera (PROTAC). Its applications lie in targeted protein degradation studies, enabling the investigation of protein function and modulation within various biological systems.
