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PARP

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  1. Inhibitor (19)


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Catalog No. Product Name Product Information
A15370

4-HQN

4-HQN has been shown to inhibit PARP (poly(ADP-ribose) synthetase) which catalyzes covalent attachment of the ADP-ribose moiety of NAD+ to various proteins. Learn More
A10019

A-966492

A-966492 displayed high potency against the poly(ADP-ribose) polymerase-1 (PARP-1) enzyme with a K(i) of 1 nM and an EC(50) of 1 nM in a whole cell assay. Learn More
A10026

ABT-888 (Veliparib)

ABT-888(Veliparib) is a potential anti-cancer drug acting as a PARP inhibitor. Learn More
A10045

AG-014699 (Rucaparib)

AG-014699 (Rucaparib) is a PARP inhibitor that inhibits poly(ADP-ribose) polymerase (PARP) is a key enzyme in DNA repair. Learn More
A10046

AG14361

AG14361 is a potent PARP inhibitor, enhanced Temozolomide (TMZ) cytotoxicity in MMR(mismatch repair)-proficient / deficient cells. Learn More
A12393

AZD-2461

AZD2461 is a novel and potent PARP inhibitor with lower affinity to P-glycoprotein. Learn More
A15024

BMN-673 8R,9S

BMN-673 (8R,9S) is the (8R,9S) enantiomer of BMN-673. BMN 673 is a novel PARP inhibitor with IC50 of 0.58 nM(PARP1). Learn More
A11243

BMN673

BMN-673 is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity. Learn More
A10164

BSI-201 (Iniparib)

BSI-201 is a potent inhibitor of PARP-1 and has been shown to cross the blood-brain barrier. Learn More
A15371

BYK 204165

BYK204165 is a cell-permeable isoquinolinedione compound that potently and selectively inhibits poly (ADP-ribose) polymerase 1 (PARP1). Learn More
A15372

BYK 49187

BYK 49187, PARP-1 and PARP-2 inhibitor (pIC50 values are 8.36 and 7.50 for cell-free recombinant PARP-1 and murine PARP-2 respectively). Learn More
A15373

DR 2313

PARP Inhibitor XIDR 2313, PARP Inhibitor XI, is a water soluble pyrimidinone compound that functions as a PARP (Poly(ADP-ribose) polymerase) inhibitor. Learn More
A15374

EB 47

EB 47 is a potent inhibitor of PARP1 with IC50 of 45 nM. Learn More
A10475

INO-1001

INO-1001 is a novel PARP inhibitor, known to sensitize cells to radiation in vitro by inhibiting the repair of DNA damage. Learn More
A11026

MK-4827

MK-4827 is a novel potent, orally bioavailable PARP-1 and PARP-2 inhibitor. Learn More
A15375

NU 1025

NU 1025 is a potent poly(ADP-ribose) polymerase (PARP) inhibitor, which potentiates the cytotoxicity of a panel of mechanistically diverse anti-cancer agents in L1210 cells. Learn More
A10111

Olaparib (AZD2281)

Olaparib (AZD2281) is an inhibitor of poly ADP ribose polymerase (PARP), an enzyme involved in DNA repair. Learn More
A12665

PJ 34 hydrochloride

PJ 34 hydrochloride is a potent inhibitor of poly(ADP-ribose) polymerase (PARP) (EC50 = 20 nM). Learn More
A10909

Tenofovir Disoproxil Fumarate

Tenofovir Disoproxil Fumarate is employed as an anti-HIV agend and a reverse transcriptase inhibitor. Learn More
A12750

UPF 1069

UPF 1069 is a selective poly(ADP-ribose) polymerase (PARP) 2 inhibitor (IC50 values are 0.3 and 8.0 μM for PARP-2 and PARP-1 respectively). Learn More

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PARP

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