Melanocortin Receptor

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  1. MC1R and MC5R antagonist

    JNJ-10229570 is a novel MC1R and MC5R antagonist was used to treat primary human sebaceous cells.
  2. MC3/4R Antagonist

    SHU 9119 is a potent human melanocortin 3 and 4 receptors (MC3/4R) antagonist and a partial MC5R agonist; with IC50 values of 0.23, 0.06, and 0.09 nM for human MC3R, MC4R and MC5R, respectively.

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