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$0.00 Calcium-Sensing Receptor
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NPS-2143 hydrochloride
Catalog No. A11505 CaSR antagonistNPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. Learn More -
NPS-2143 (SB-262470)
Catalog No. A11140 CaSR antagonistNPS-2143 is a selective Ca2+-sensing receptor antagonist, shown to block increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells with an IC50 of 43 nM. Learn More -
AMG-073 HCl (Cinacalcet HCl)
Catalog No. A10219 CaSR activatorAMG-073 HCl (Cinacalcet HCl) represents a new class of compounds for the treatment of hyperparathyroidism known as calcimimetics, which reduce parathyroid hormone (PTH) synthesis and secretion by increasing the sensitivity of the parathyroid calcium-sensing receptor (CaR) to extracellular calcium. Learn More -
Strontium ranelate (Protelos)
Catalog No. A11681 CaSR agonistStrontium ranelate is an antiosteoporotic agent which both increases bone formation and reduces bone resorption, resulting in a rebalance of bone turnover in favor of bone formation. This is similar to the effects of choline stabilized orthosilicic acid. Learn More -
AMG 073 (Cinacalcet)
Catalog No. A11314 CaSR activatorAMG-073 (Cinacalcet) represents a new class of compounds for the treatment of hyperparathyroidism. Learn More -
Evocalcet
Catalog No. A17003 CaSR agonistEvocalcet is a calcium-sensing receptor agonist. The calcium-sensing receptor (CaSR) is a Class C G-protein coupled receptor which senses extracellular levels of calcium ion. Learn More
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