CGRP Receptor

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  1. CGRP 8-37 (human)

    Catalog No. A16949
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    CGRP receptor antagonist
    HCGRP-(8-37) is a human calcitonin gene-related peptide (hCGRP) fragment and also an antagonist of CGRP receptor. Sequence: Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe ;VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF . Learn More
  2. Olcegepant

    Catalog No. A11512
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    CGRP1 receptor
    Olcegepant is a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and Ki of 14.4 pM for human CGRP. Learn More
  3. Ubrogepant

    Catalog No. A21670
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    CGRP antagonist
    Ubrogepant (MK-1602) is a novel oral calcitonin gene-related peptide receptor (CGRP) antagonist in development for acute treatment of migraine. Learn More
  4. Olcegepant hydrochloride

    Catalog No. A21900
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    CGRP1 receptor antagonist
    Olcegepant hydrochloride is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor with IC50 of 0.03 nM and with a Ki of 14.4 pM for human CGRP. Learn More
  5. MK 3207 HCl

    Catalog No. A10598
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    CGRP Receptor antagonist
    MK 3207 hydrochloride is a potent CGRP receptor antagonist with IC50 of 0.12 nM. Learn More
  6. MK-0974 (Telcagepant)

    Catalog No. A11255
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    CGRP receptor antagonist
    MK-0974 (Telcagepant) is a potent and selective antagonist of the human and rhesus CGRP receptors. Learn More
  7. BMS-927711

    Catalog No. A13102
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    CGRP receptor antagonist
    BMS-927711 is a potent, selective, competitive human calcitonin gene-related peptide (CGRP) receptor antagonist that has shown in vivo efficacy without vasoconstrictor effect. Learn More
  8. MK-3207

    Catalog No. A15165
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    CGRP Receptor antagonist
    MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC50= 0.12 nM; Ki value= 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3. Learn More

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