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MK 3207 HCl

CGRP Receptor antagonist

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Catalog No. A10598

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
MK 3207 hydrochloride 5mg A10598-5
MK 3207 hydrochloride 10mg A10598-10
MK 3207 hydrochloride 50mg A10598-50
MK 3207 hydrochloride 100mg A10598-100
MK 3207 HCl 10mM * 1mL in DMSO A10598-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

MK 3207 hydrochloride is a potent CGRP receptor antagonist with IC50 of 0.12 nM.

MK 3207 HCl

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Publications citing Adooq Products
MK 3207 HCl Citations (1)
  • Marlene Dallmayer, .et al. Targeting the CALCB/RAMP1-axis inhibits growth of Ewing sarcoma, bioRxiv, 2018, 2018

Chemical Information

Catalog Num A10598
Actions Antagonist
M. Wt 594.1
Formula C31H30ClF2N5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 957116-20-0
Synonyms MK3207, MK-3207
SMILES C1CCC2(C1)C(=O)N([[email protected]@H](CN2)C3=CC(=CC(=C3)F)F)CC(=O)NC4=CC5=C(C[[email protected]@]6(C5)C7=C(NC6=O)N=CC=C7)C=C4.Cl

Biological Activity

MK 3207 hydrochloride is a potent CGRP receptor antagonist with IC50 of 0.12 nM.
0.12 nM


Solubility (25°C) * In vitro DMSO 119 mg/mL (200.31 mM)
Water 5 mg/mL (8.41 mM)
Ethanol 119 mg/mL (200.31 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.83 mL 84.16 mL 168.32mL
0.5 mM 3.37 mL 16.83 mL 33.66 mL
1 mM 1.68 mL 8.42 mL 16.83 mL
5 mM 0.34 mL 1.68 mL 3.37 mL

*The above data is based on the productmolecular weight 594.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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