All Dyes

Cat. No.

A44291

CAS No.

1245606-71-6

TPE-MI

Synonyms: Tetraphenylethene maleimide

TPE-MI (Tetraphenylethene maleimide) is a fluorogenic dye that serves as a thiol probe for evaluating unfolded protein load and proteostasis in cellular contexts. Its excitation and emission wavelengths at 350 nm and 470 nm respectively enable sensitive detection of proteostasis imbalances in induced pluripotent stem cell models of Huntington’s disease, as well as in cells expressing mutant Huntington exon 1 prior to aggregate formation. Additionally, TPE-MI is valuable for assessing protein damage in studies involving dihydroartemisinin and the malaria parasite Plasmodium falciparum.

Cat. No.

A44294

CAS No.

1564286-24-3

Cy5-DBCO

Synonyms: DBCO-Sulfo-Cy5

Cy5-DBCO is a near-infrared fluorescent dye that features an absorption maximum at 646 nm and emission maximum at 670 nm. This compound functions as a click chemistry reagent, containing a DBCO group that readily participates in strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. It is particularly useful in bioconjugation applications, facilitating the labeling of proteins and other biomolecules for imaging and tracking studies, although it is not recommended for staining intracellular components in permeabilized cells due to potential high background.

Cat. No.

A44295

CAS No.

1782950-79-1

DBCO-Cy3

Synonyms: DBCO-Sulfo-Cy3

DBCO-Cy3 is an orange fluorescent dye derived from the Cyanine3 fluorophore, exhibiting stable fluorescence across a pH range of 4-10. It has an excitation maximum at 555 nm and an emission maximum at 580 nm, making it suitable for various fluorescence applications. DBCO-Cy3 features rapid reaction kinetics and is compatible with standard fluorescence instruments. As a click chemistry reagent, it contains a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules, enabling targeted labeling and imaging in biochemical research.

Cat. No.

A44296

CAS No.

76877-33-3

CPM

CPM is a maleimide derivative that functions as a blue fluorescent thiol-reactive dye, with excitation and emission maxima at 387 and 463 nm, respectively. This compound is primarily utilized for the selective labeling of sulfhydryl groups in proteins and peptides, enabling the study of protein interactions, dynamics, and functions in various biological contexts. Its applications are valuable in biochemistry, cell biology, and proteomics research.

Cat. No.

A44297

CAS No.

10199-89-0

NBD-Cl

Synonyms: NBD chloride

NBD-Cl is a nonfluorescent reagent that undergoes a transformation to become highly fluorescent upon reacting with thiols or amino groups. This unique property makes it an invaluable tool for labeling and detecting biomolecules in various biochemical assays. NBD-Cl is widely used in the characterization of proteins and peptides, facilitating studies in areas such as biochemistry, molecular biology, and pharmacology.

Cat. No.

A44298

CAS No.

150810-68-7

5-TAMRA-SE

Synonyms: 5-TAMRA-NHS ester; 5-Carboxytetramethylrhodamine succinimidyl ester

5-TAMRA-SE is an amine-reactive fluorescent agent that forms stable conjugates, exhibiting bright, pH-insensitive orange-red fluorescence with excellent photostability (Ex/Em = 565/580 nm). This reagent is ideal for a variety of applications, including protein labeling, cellular imaging, and flow cytometry, enabling researchers to visualize biological processes with precision and clarity.

Cat. No.

A44299

CAS No.

2363751-90-8

Rhodamine-N3 chloride

Rhodamine-N3 chloride is a fluorescent dye with a primary mechanism based on its azide functionalities. This reagent is designed for the labeling of biomolecules containing alkyne groups through copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. With an excitation/emission wavelength of 544/576 nm, Rhodamine-N3 chloride is ideal for various applications in bioimaging and chemical biology studies.

Cat. No.

A44300

CAS No.

11016-15-2

C-Phycocyanin

Synonyms: C-PC

C-Phycocyanin (C-PC) is a water-soluble protein pigment primarily targeted for its antioxidant properties. It demonstrates significant biological activities, including the ability to scavenge free radicals and modulate immune responses. C-PC is commonly utilized in research applications related to dietary supplements, natural colorants, and potential therapeutic agents in oxidative stress-related conditions.

Cat. No.

A44301

CAS No.

124387-19-5

5(6)-CFDA

Synonyms: 5-(6)-Carboxyfluorescein diacetate; CFDA

5(6)-CFDA is a fluorescent dye that acts through passive diffusion into cells, where it is hydrolyzed by intracellular non-specific lipases into carboxyl fluorescein (CF). The carboxylate group of CF imparts a negative charge, enhancing its retention within cells compared to traditional fluorescein dyes. This property makes 5(6)-CFDA particularly useful for various biological applications such as cell tracking, apoptosis detection, and cellular viability assays in live cell imaging studies.

Cat. No.

A44302

CAS No.

1407523-31-2

Fl-DIBO

Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective fluorescent probe specifically designed for azide compounds. It enables the rapid formation of highly fluorescent products upon reaction with azides, exhibiting maximum emission at 469 nm and excitation at 363 nm. This probe is ideal for labeling diazo-tagged proteins, providing minimal background signal interference. As a click chemistry reagent, Fl-DIBO contains an alkyne moiety, facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules, making it a valuable tool for various bioconjugation applications in chemical biology.

Cat. No.

A44303

CAS No.

847180-48-7

Cy7.5

Cy7.5 is a cyanine dye characterized by its long wavelength and high extinction coefficient, making it an effective fluorescence labeling agent. It exhibits excellent water solubility and adjustable absorption and emission properties, facilitating simple labeling procedures for proteins, antibodies, and small molecular compounds. This compound is widely utilized in bioconjugation applications, providing researchers with robust means for the visualization and quantification of biomolecules in various biological assays.

Cat. No.

A44304

CAS No.

38597-12-5

4-Methylumbelliferyl-α-D-galactopyranoside

Synonyms: 4MU-α-Gal

4-Methylumbelliferyl-α-D-galactopyranoside is a pro-fluorogenic substrate specifically designed for α-galactosidase A (GLA) activity. Upon enzymatic cleavage by GLA, this compound yields galactose and the fluorescent product 4-methylumbelliferone, which enables the visualization and quantification of enzymatic activity. It is widely utilized in biochemical assays and research applications to study GLA function and activity.

Cat. No.

A44305

CAS No.

1811539-59-9

Janelia Fluor® 646, SE

Synonyms: JF646; SE; NHS

Janelia Fluor® 646, SE is a red fluorescent dye that facilitates cellular imaging applications. This compound exhibits excellent photostability and brightness, making it ideal for high-resolution visualization of biological specimens. Its unique properties enable researchers to conduct advanced studies in cellular dynamics, protein localization, and other fluorescence-based research endeavors.

Cat. No.

A44306

CAS No.

1267539-32-1

Cyanine5 azide chloride

Cyanine5 azide chloride is a versatile fluorescent dye featuring an azide functional group, making it amenable to copper-catalyzed azide-alkyne cycloaddition (CuAAC). With excitation and emission wavelengths of 646 nm and 662 nm, respectively, it is highly effective for various biological imaging applications. Its reactive profile allows for coupling with terminal alkynes, as well as ring strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN-containing molecules, thereby expanding its utility in chemical biology and conjugation strategies.

Cat. No.

A44308

CAS No.

150173-78-7

BODIPY 576/589

BODIPY 576/589 is a near-infrared (NIR) fluorophore that exhibits strong fluorescence with an emission and excitation maximum at 589 nm and 576 nm, respectively. This compound features a free carboxylic acid (-COOH) group, making it suitable for various bioconjugation applications. BODIPY 576/589 is particularly useful in fluorescence imaging, enabling sensitive detection of biomolecules in live cells and tissues. Its long-wavelength properties allow for reduced background fluorescence, facilitating enhanced signal visibility in biological assays.

Cat. No.

A44309

CAS No.

246256-50-8

5(6)-TAMRA SE

Synonyms: 5(6)-Carboxytetramethylrhodamine N-succinimidyl ester

5(6)-TAMRA SE is a fluorescent dye that emits red fluorescence, primarily targeting oligonucleotides. Its ability to bind specifically to these molecules makes it ideal for applications in DNA sequencing, facilitating the analysis of genetic material. Additionally, 5(6)-TAMRA SE is employed in cancer research, with optimal excitation and emission wavelengths at 565 nm and 580 nm, respectively.

Cat. No.

A44310

CAS No.

86636-92-2

Acrylodan

Acrylodan is a fluorescent dye that exhibits sensitivity to the local dipolarity and dynamics in the environment surrounding Cys34 upon reaction with thiols. This compound serves as a valuable tool for studying protein conformation and dynamics in biochemical research. Its characteristics make it suitable for applications in fluorescence microscopy and spectroscopy, enabling researchers to probe molecular interactions and conformational changes in biological systems.

Cat. No.

A44311

CAS No.

63368-54-7

5-IAF

Synonyms: 5-Iodoacetamidofluorescein

5-IAF (5-Iodoacetamidofluorescein) is a fluorescent probe that selectively labels proteins and other molecules containing free thiols, particularly cysteine side chains. Its utility in labeling enables the visualization and tracking of thiol-containing biomolecules in various biological studies. This compound is instrumental in protein interaction studies and cellular imaging applications, providing insights into protein dynamics and cellular processes.

Cat. No.

A44312

CAS No.

2409591-45-1

Cyanine5.5 maleimide chloride

Synonyms: Cy5.5 maleimide chloride

Cyanine5.5 maleimide chloride is a fluorescent dye known for its ability to label biomolecules effectively. This dye exhibits long wavelength absorption and emission profiles, high extinction coefficients, and water solubility, making it suitable for various applications in biological research. It is commonly used for the labeling of proteins, antibodies, and small molecular compounds through straightforward coupling reactions. Cyanine5.5 maleimide chloride facilitates enhanced visualization in fluorescence microscopy and flow cytometry, enabling researchers to study protein interactions and cellular processes with precision.

Cat. No.

A44313

CAS No.

91366-65-3

4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole

Synonyms: ABD-F

4-(Aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole (ABD-F) is a fluorescent reagent specifically designed for the sensitive detection of thiol groups, exhibiting excitation and emission wavelengths of 380 nm and 510 nm, respectively. This compound displays a low fluorescence background, enhancing signal clarity in analytical applications. Its robust stability as a fluorophore makes it suitable for various biochemical assays and research applications involving thiol-based biomolecules.

Cat. No.

A44314

CAS No.

216699-35-3

5-ROX

Synonyms: 5-Carboxy-X-rhodamine

5-ROX (5-Carboxy-X-rhodamine) is a rhodamine dye known for its strong fluorescence properties in aqueous buffers. It exhibits an excitation wavelength (λexit) of 580 nm and an emission wavelength (λemit) of 604 nm, making it suitable for a variety of fluorescence applications. This dye is commonly utilized in molecular biology for labeling and tracking biomolecules, enabling enhanced visualization in imaging and detection assays.

Cat. No.

A44316

CAS No.

78044-20-9

Fluorescein hydrazide

Fluorescein hydrazide is a highly sensitive fluorescent probe designed for the detection of Hg2+ and Co2+ ions through significant colorimetric and fluorometric changes. This compound is synthesized via the reaction of fluorescein with hydrazine, enabling its application in tracing metal ions in biochemical assays. Exhibiting an excitation wavelength of 508 nm and an emission wavelength of 531 nm, fluorescein hydrazide is an essential tool in environmental monitoring and biological research applications focused on metal ion detection.

Cat. No.

A44317

CAS No.

1176905-54-6

DAz-2

DAz-2 is a sulfonic acid probe designed for the direct detection of sulfonic acid-modified proteins in living cells. This cell-permeable reagent facilitates real-time imaging and analysis of post-translational modifications, supporting research in cellular signaling and protein interactions. It is an invaluable tool for studies involving protein modification and function in dynamic cellular environments.

Cat. No.

A44318

CAS No.

80883-54-1

7-Dimethylaminocoumarin-4-acetic acid

7-Dimethylaminocoumarin-4-acetic acid is a fluorescent dye that emits high-intensity fluorescence upon excitation. It is commonly used in biological imaging and assay development due to its excellent photostability and water solubility. This compound can facilitate the study of cellular processes and molecular interactions, making it valuable for researchers in the fields of biochemistry and molecular biology.

Cat. No.

A44319

CAS No.

49759-20-8

N-(9-Acridinyl)maleimide

N-(9-Acridinyl)maleimide is a maleimide-based fluorescent thiol reagent that functions primarily through covalent coupling with thiol compounds. While N-(9-Acridinyl)maleimide itself exhibits minimal fluorescence, its conjugates display pronounced blue fluorescence, making it an effective tool for monitoring thiol-containing biomolecules. This reagent is commonly utilized for the fluorometric determination of cysteine and glutathione, aiding in the study of redox biology and thiol-related processes.