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All Dyes is the single product list for the Fluorescent Dyes, Probes & Stains section. Many dyes here have no application or dye-family subcategory, so the list is the broadest way to browse the range. It suits searches by product name when the required dye is already known. Examples range from the near-infrared cyanine indocyanine green and the ratiometric calcium indicator Fura-2 pentapotassium to the nucleic acid stains Hoechst 33258 trihydrochloride and SYBR Green II. Classical stains such as hematoxylin, reactive labeling dyes and enzyme substrates are listed alongside them. For selection by task or by core structure, the parent Fluorescent Dyes, Probes & Stains page groups dyes by application and dye family.
510 Calibration Probe is a chemiluminescent group designed for in vivo imaging applications. With an emission maximum around 520 nm, this probe facilitates the detection and visualization of biological processes, enhancing the accuracy of imaging studies. Its reliable performance makes it suitable for various research applications in the fields of molecular biology and pharmacology.
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Apotracker Red is a fluorogenic dye designed to target apoptotic cells through its specific binding to phosphatidylserine (PtdSer) on the cell surface. Exhibiting excitation and emission wavelengths of 561 nm and 610 nm, respectively, Apotracker Red provides rapid and selective staining of apoptotic cells while leaving viable cells unmarked. This reagent is particularly useful for real-time detection of cancer cell death, facilitating insights into apoptosis-related research.
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5-JOE azide is a fluorescent dye that emits in the yellow region of the spectrum. It features an azide group that participates in Click Chemistry reactions with alkynes, BCN, or DBCO, resulting in a stable triazole linkage. This compound is valuable for various biological applications, including labeling and tracking of biomolecules in cellular and molecular biology studies.
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Synonyms: BHQ-1 DMT amidite
DMT-BH1 amidite is a prominent fluorescent dye characterized by its function as a dark quencher with a broad absorption profile, peaking in the green to yellow regions of the visible spectrum. This reagent is primarily utilized in the synthesis of dual-labeled oligonucleotide probes, particularly for quantitative PCR (qPCR) applications, incorporating the 5'-quencher DusQ 1. Its ability to facilitate Förster Resonance Energy Transfer (FRET) enhances multiplexing capabilities in various assay formats, making it an essential tool for advanced genetic research.
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SIMA phosphoramidite, 6-isomer, is a xanthene-based fluorescent dye exhibiting spectral properties comparable to HEX, combined with an enhanced quantum yield. This compound demonstrates superior stability during deprotection in alkaline environments, making it an ideal choice for applications in nucleic acid labeling and fluorescent assays. Its robust performance enables reliable detection in various research settings.
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BP Fluor 532 NHS ester is an amine-reactive fluorescent dye designed for labeling biomolecules, particularly proteins and antibodies, through primary amines. It exhibits bright yellow fluorescence and maintains stable emission across a wide pH range (4 to 10), making it suitable for diverse biological applications. The dye forms a stable covalent amide bond, with optimal labeling efficiency achieved at pH 7-9. BP Fluor 532 is compatible with frequency-doubled Nd:YAG laser excitation and is widely utilized in imaging techniques and flow cytometry to enhance signal stability.
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Synonyms: BHQ-2 DMT amidite
DMT-BH2 amidite is a black quencher dye designed for the synthesis of dual-labeled oligonucleotide probes with a 5'-quencher suitable for quantitative PCR (qPCR). This amidite effectively quenches fluorophores such as HEX, JOE, ROX, and Cyanine5, making it optimal for applications involving emissions in the orange and red regions of the spectrum. Its selective quenching properties enhance the sensitivity and specificity of nucleic acid detection assays.
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Fluorescein hydrazide (3,6-Dihydroxyxanthane) is a fluorescein dye that primarily targets reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). This compound exhibits strong fluorescence properties, making it suitable for fluorophotometric assays in various biological studies. It is widely used in research applications focused on oxidative stress, cellular signaling, and ROS detection.
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2-Amino-5-methoxybenzamidoxime is a fluorescent dye utilized for the detection of various ketones, such as aromatic, hydroxyl, cyclic, and aliphatic ketones. This compound exhibits distinct fluorescence properties, with an excitation maximum at 389 nm and an emission maximum at 515 nm, making it suitable for applications in analytical chemistry and biochemistry for visualizing and quantifying ketone compounds. Its sensitivity and specificity make it an effective tool for researchers studying ketone-related biochemical processes.
PSP is a two-photon fluorescent probe designed for the selective and sensitive detection of hydrogen sulfide (H2Sn) in live cells and tumor spheroids, with excitation and emission wavelengths of 440 nm and 640 nm, respectively. This reagent is particularly valuable in ferroptosis research, enabling real-time monitoring of reactive sulfur species within biological systems. Its high selectivity and sensitivity make PSP an essential tool for studying cellular pathways and mechanisms associated with oxidative stress and cell death.
Synonyms: APG-1 (TMA)
Asante Potassium Green-1 (TMA) is a cell-impermeable fluorescent indicator designed to selectively detect potassium ions (K+) with an excitation wavelength of 525 nm and emission wavelength of 545 nm. This compound allows researchers to monitor intracellular potassium levels with high sensitivity and specificity, making it invaluable for studies involving ion transport, cellular signaling, and physiology. Its utility in real-time fluorescence imaging facilitates investigations into potassium's role in various biological processes and disease states.
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Synonyms: APG-1 AM
Asante potassium green-1 AM is a cell-permeable potassium (K+) sensitive fluorescent indicator with an excitation/emission wavelength of 525/545 nm. This reagent enables the visualization and quantification of potassium ion fluctuations within live cells, making it suitable for studies in neurobiology, cardiac research, and cellular signaling. Its high sensitivity to K+ concentrations facilitates investigations into ion channel activity and cellular excitability, enhancing understanding of various physiological processes.
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Sulfo-QSY21-NHS is a fluorescent dye featuring an N-hydroxysuccinimide (NHS) moiety that readily reacts with amine groups (-NH2) present in proteins and other biomolecules, resulting in stable amide bond formation. This compound is commonly utilized in the synthesis of activity-based probes (ABPs), facilitating the study of enzyme activity and protein interactions in various biological research applications. Its robust fluorescent properties make it an ideal choice for high-sensitivity detection methods in biochemical assays.
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Disperse Red 343 is an azo dye that primarily targets polyester fibers, functioning as a dyeing agent in textile applications. It exhibits strong color fastness properties, making it ideal for use in synthetic fabric coloration. Research applications may include studies on dye absorption, migration, and the environmental impact of azo dye usage in textile manufacturing processes.
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Disperse Red 153 is an azo dye characterized by its vibrant red color and application in various industries. This compound demonstrates excellent compatibility with plastics and textiles, making it suitable for coloring applications in these materials. Additionally, its stability and non-volatile properties extend its utility to cosmetic formulations.
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Synonyms: APG-2 Acetoxymethyl ester
IPG-2 AM is a membrane-permeable potassium (K+) fluorescent indicator. This reagent is designed to enable the detection and quantification of intracellular potassium ion concentrations in live cells through fluorescence microscopy. Its application is crucial in studies related to ion channel activity, cellular signaling, and neuronal function.
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AIE-GA is a fluorescent probe designed to target the Golgi apparatus, emitting fluorescence in the green channel with excitation at 405 nm and an emission range of 500-700 nm. This probe exhibits favorable binding affinity to cyclooxygenase-2 (COX-2), specifically interacting with its catalytic site. AIE-GA serves as a valuable tool for cellular imaging and studies involving the Golgi apparatus and COX-2, facilitating research in inflammation and related pathways.
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MIT-PZR is a mitochondria-targeted fluorescent probe designed for effective imaging applications. With low cytotoxicity, it is suitable for use in live-cell experiments and in vivo imaging studies. This probe exhibits excitation and emission maxima at 485 nm and 705 nm, respectively, enabling the visualization of mitochondrial activity and dynamics in real-time.
Mito-CCY is a mitochondria-targeted fluorescent dye characterized by its near-infrared (NIR) absorption properties. This cryptocyanine probe exhibits high photothermal conversion efficiency and demonstrates good biological compatibility in vitro. Additionally, Mito-CCY induces photoinduced cytotoxicity in HeLa cells, making it a valuable tool for studies in mitochondrial dynamics and photothermal therapy applications.
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CellTracker Orange CMRA Dye is a fluorescent dye designed for cellular imaging and monitoring. It allows for the visualization of cellular movement and localization, providing insights into cell dynamics and behavior. This reagent is particularly useful in studies requiring tracking of live cells in a variety of biological contexts.
7-Methoxycoumarin-3-carboxylic acid serves as a precursor for the synthesis of hydrophilic dye compounds. The resultant dye demonstrates a uniform distribution within cellular environments, making it an effective probe for assessing viscosity in the cytoplasm. This compound is valuable for various applications in cellular imaging and biophysical studies.
m-Cresol purple is a pH indicator dye that exhibits halochromic properties, allowing for a clear visual transition in the neutral pH range. Its large cross-section enhances its sensitivity, making it an effective tool for monitoring pH changes in various biochemical assays. This compound is commonly utilized in laboratory settings for applications such as titrations, biological studies, and environmental analyses.
Propyl Red is a versatile dye primarily used for biological staining. This compound facilitates the observation and analysis of cellular structures, enables biomolecule tracking, and assists in the evaluation of cell functions, making it valuable in both basic and clinical research applications. Additionally, Propyl Red is utilized for distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Beyond its biological uses, it finds applications in traditional textile dyeing and emerging technologies, including functional textiles and dye-sensitized solar cells.
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PY-PAP is a photoactivatable affinity probe designed for the identification of target proteins through ultraviolet crosslinking. This compound effectively retains the ability to activate YAP transcriptional activity while specifically labeling cathepsin D (CTSD) and annexin A2 (ANXA2) in 293A cells. PY-PAP serves as a critical tool for delineating the interactions and specific targeting of proteins like ANXA2, thereby facilitating research into cellular signaling pathways and protein function.
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Synonyms: 4,4'-DiOMEA; Nasutin C
4,4'-Di-O-methylellagic acid is a blue-fluorescent compound primarily isolated from Australian termites. It exhibits inhibitory effects on colon cancer cell proliferation, primarily through the modulation of the Wnt signaling pathway. This makes 4,4'-Di-O-methylellagic acid a valuable tool in cancer research and studies exploring molecular mechanisms of fluorescence in biological applications.
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