Cyanine Dyes

Cat. No.

B11101

CAS No.

3091879-31-8

Cyanine 7 free acid bromide

Cyanine 7 free acid bromide is a near-infrared fluorescent dye that targets amine groups on biomolecules, including antibodies, nucleic acids, and proteins. This reagent facilitates the labeling process, allowing for sensitive detection using various fluorescence techniques such as microscopy and flow cytometry. Its application in biological research supports studies in cellular imaging and molecular interaction analysis.

Cat. No.

B11112

CAS No.

2756733-39-6

Cy5.5 bis-COOH bromide

Cy5.5 bis-COOH bromide is a fluorescent dye that features carboxyl groups enabling the formation of covalent bonds with amines. It exhibits absorption and emission maxima at 680 nm and 710 nm, respectively. This reagent is ideal for applications in fluorescence imaging, providing enhanced sensitivity and specificity in labeling and detecting biomolecules in various biological assays.

Cat. No.

B11134

CAS No.

1850419-05-4

ASMI

ASMI is a ratiometric, two-photon excited fluorescent probe that targets mitochondrial cysteine. It features a biocompatible merocyanine fluorophore and an acrylate moiety for selective thiol reactivity. ASMI enables high-contrast, bright imaging of living cells and intact tissues, with a depth of up to 150 μm, facilitating rapid monitoring of cellular redox states. The probe exhibits a two-photon action cross section (Φσmax) of 65.2 GM at an excitation wavelength (λex) of 740 nm, making it suitable for advanced fluorescence microscopy applications.

Cat. No.

B11145

CAS No.

3091879-88-5

Meso-Cl cyanine 7.5 free acid chloride

Meso-Cl cyanine 7.5 free acid chloride is a fluorescent dye primarily targeting amine groups in biological molecules. This reagent effectively labels antibodies, nucleic acids, and proteins, enabling detailed studies in various applications, including microscopy and flow cytometry. With excitation and emission wavelengths of 815 nm and 825 nm, respectively, it provides high sensitivity and versatility for fluorescence detection techniques in chemical research.

Cat. No.

B11147

CAS No.

3091879-41-0

Cyanine 5.5 DBCO chloride

Cyanine 5.5 DBCO chloride is a versatile click chemistry reagent featuring a cycloalkyne moiety that enables efficient, copper-free bioconjugation. This compound serves as a linker for the Cyanine 5.5 fluorophore, providing excellent stability and fast reaction kinetics. With excitation and emission wavelengths of 680 nm and 715 nm, respectively, it is ideal for applications in fluorescent imaging and labeling of lipids and biomolecules in various biological research contexts.

Cat. No.

B11164

CAS No.

3091879-86-3

Sulfo-Cy3(Me)COOH potassium

Sulfo-Cy3(Me)COOH potassium is a sulfo-Cyanine 3 derivative designed as a fluorescent dye. This compound exhibits strong orange fluorescence, making it suitable for labeling proteins and nucleic acids with an excitation wavelength of 554 nm and an emission wavelength of 568 nm. It is commonly utilized in various biological applications, including fluorescence microscopy and flow cytometry, facilitating the visualization and tracking of biomolecules in research studies.

Cat. No.

B11169

CAS No.

3077081-59-2

Cyanine 3.5 maleimide chloride

Cyanine 3.5 maleimide chloride is a fluorescent dye that targets thiol groups in proteins for specific labeling applications. It exhibits advantageous properties, including a long wavelength, adjustable absorption and emission spectra, high extinction coefficient, and good water solubility. This dye is commonly utilized in the labeling of proteins, antibodies, and small molecular compounds, facilitating the study of protein dynamics and interactions through fluorescence techniques. The labeling process is straightforward, typically involving a simple mixing reaction with the target biomolecule.

Cat. No.

B11182

CAS No.

2204261-66-3

Cyanine 5 azide

Cyanine 5 azide is a fluorescent dye featuring an azide functional group, primarily serving as a click chemistry reagent. This compound can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. With excitation and emission wavelengths of 633 nm and 670 nm, respectively, it is valuable for a range of biological applications, including labeling and imaging studies.

Cat. No.

B11189

CAS No.

3091879-96-5

Cyanine 7.5 NHS chloride

Cyanine 7.5 NHS chloride is a fluorescent dye that functions as a reactive electrophile, allowing for selective conjugation to amine-containing biomolecules. This compound is particularly useful in the development of fluorescent copolymers, such as mPEG-b-PDPA-Cy7.5, enhancing their imaging capabilities. Its fluorescent properties, with excitation and emission wavelengths of 780 nm and 820 nm respectively, make it suitable for various fluorescence imaging applications in biological research.

Cat. No.

B11233

CAS No.

1888323-45-2

GSH Tracker Probe

GSH Tracker Probe (CPDSA) is a cyanine-based fluorescent probe designed for the selective detection of glutathione (GSH) with near-infrared (NIR) emission characteristics. Excited at 635 nm and emitting between 655-755 nm, this probe enables real-time monitoring and imaging of GSH levels in live cells and in vivo models. It serves as a valuable tool for studies related to oxidative stress, cellular redox states, and various pathological conditions linked to glutathione alterations.

Cat. No.

B11236

CAS No.

3077081-53-6

Cyanine 3.5 azide

Cyanine 3.5 azide is a fluorescent dye featuring an azide functional group, making it suitable for click chemistry applications. It effectively participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing compounds, as well as in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This versatile reagent exhibits excitation and emission maxima at 591 nm and 604 nm, respectively, and is ideal for labeling and imaging studies in chemical biology and biomolecular research.

Cat. No.

B11239

CAS No.

3091879-84-1

Meso-Cl cyanine 7 free acid chloride

Meso-Cl cyanine 7 free acid chloride is a fluorescent dye targeting amine groups on biomolecules. It is particularly useful for labeling antibodies, nucleic acids, and proteins, enabling enhanced visualization in various fluorescence detection techniques including microscopy and flow cytometry. The dye exhibits excitation and emission wavelengths of 778 nm and 805 nm, respectively, making it suitable for multiplex applications in biological research.

Cat. No.

B11258

CAS No.

3091880-03-1

Cyanine 7.5 maleimide chloride

Cyanine 7.5 maleimide chloride is a near-infrared fluorescent dye, designed for specific labeling applications in biochemical research. This compound exhibits exceptional properties, including a long wavelength, high extinction coefficient, and excellent water solubility, making it an ideal choice for the selective labeling of proteins, antibodies, and small molecules. It can facilitate efficient conjugation through a straightforward mixing reaction, enabling researchers to visualize and track biomolecules with precision in various applications such as cellular imaging and protein interaction studies.

Cat. No.

B11267

CAS No.

3077081-67-2

(E)-Cyanine 3.5 chloride

Synonyms: (E)-Cy3.5 NHS ester chloride; (E)-Cy 3.5 chloride

(E)-Cyanine 3.5 chloride is a fluorescent dye that features a N-hydroxysuccinimide (NHS) moiety, enabling efficient labeling of biomolecules. The NHS group allows for the formation of stable ester bonds upon reaction with amines, making it suitable for conjugation applications. With excitation and emission wavelengths of 586 nm and 612 nm, respectively, (E)-Cyanine 3.5 chloride is highly useful in various biological imaging and assay applications, including fluorescence microscopy and flow cytometry.

Cat. No.

B11311

CAS No.

2236573-39-8

Sulfo-Cy7 amine

Sulfo-Cy7 amine is a near-infrared (NIR) fluorescent dye featuring a free amine group, allowing for conjugation with various reactive functionalities such as NHS esters and epoxides. This compound serves as an essential tool for labeling and tracking biological targets through electrophilic reactions and enzymatic transamination processes. Its capability to improve detection sensitivity makes it valuable in applications such as in vivo imaging and cell tracking in various research fields.

Cat. No.

B11316

CAS No.

2892098-34-7

Cy3 NHS ester bromide

Synonyms: Cyanine3 NHS ester bromide

Cy3 NHS ester bromide is a cyanine dye characterized by its ability to covalently label biomolecules via amine groups. This compound exhibits strong long-wavelength fluorescence with high extinction coefficients, making it suitable for sensitive detection applications. Cy3 NHS ester is widely utilized in various research fields, including protein labeling, antibody conjugation, and small molecule tagging, facilitating advanced studies in cell biology, immunology, and molecular imaging. The labeling reaction is straightforward, enabling efficient coupling for diverse experimental setups.

Cat. No.

B11321

CAS No.

54268-70-1

Cy5 dimethyl

Cy5 dimethyl is a non-reactive fluorescent dye primarily used for instrument calibration and control sample preparation. Although it exhibits limited water solubility, it can be effectively dissolved in organic solvent mixtures such as DMF, DMSO, and alcohols. This versatile dye is essential for various applications in fluorescence imaging and research involving fluorescent labeling techniques.

Cat. No.

B11334

CAS No.

1144107-79-8

Cy3.5 carboxylic acid

Cy3.5 carboxylic acid is a fluorescent dye characterized by its carboxylic acid functional group, which readily engages with amines to form stable amide bonds. As a cyanine dye, it exhibits excitation and emission maxima at 576 nm and 603 nm, respectively. This dye is commonly utilized in various biological research applications, including imaging, labeling, and tracking of biomolecules in cellular assays and fluorescence microscopy. Its effective fluorescence characteristics make it an ideal choice for studies requiring precise visualization of target molecules.

Cat. No.

B11337

CAS No.

871514-32-8

Cy3 hydrazide

Cy3 hydrazide is a cyanine dye linker designed for the selective labeling of carbonyl-containing molecules, including aldehydes and ketones. This reagent effectively labels proteins such as antibodies and glycoproteins following periodate oxidation, as well as proteins affected by oxidative stress or deamination. Cy3 hydrazide is suitable for various fluorescent applications and is compatible with a wide range of fluorescence instrumentation, facilitating advanced biochemical and cellular studies.

Cat. No.

B11342

CAS No.

2394903-71-8

(Z)-Thiazole Orange iodide

(Z)-Thiazole Orange iodide is a fluorescent dye primarily utilized for nucleic acid detection. Its fluorescence is enhanced significantly upon binding to double-stranded DNA and RNA, increasing by up to a thousandfold in these environments. With a maximum absorption wavelength of 509 nm and an emission peak at 532 nm, this dye is valuable for applications such as determining reticulocyte percentages in human peripheral blood using microscopy and flow cytometry.

Cat. No.

B11364

CAS No.

2768-90-3

Pinacyanol chloride

Synonyms: Quinaldine blue

Pinacyanol chloride is a cyanine dye primarily utilized for its staining properties. It exhibits strong affinity for cellular components, making it effective in staining chromosomes in histological studies and bacteria in biochemical assays. This reagent is instrumental in enhancing the visualization of cell structures, aiding researchers in cellular and microbiological investigations.

Cat. No.

B11374

CAS No.

210834-26-7

Sulfo Cy5.5-COOH

Sulfo-Cy5.5-COOH is a sulfonated fluorescent dye characterized by the presence of both a sulfonic acid group and a carboxylic acid group. This dye exhibits strong fluorescence in the near-infrared region, making it suitable for applications requiring deep tissue penetration. It is commonly utilized in in vivo imaging, molecular labeling, and compatibility with various bioconjugation techniques.

Cat. No.

B11380

CAS No.

2714419-16-4

Tetra-sulfo-Cy7 DBCO

Tetra-sulfo-Cy7 DBCO is a highly fluorescent near-infrared dye designed for applications requiring low background noise and high sensitivity. This water-soluble, hydrophilic probe exhibits remarkable photostability and maintains consistent fluorescence across a pH range of 4 to 10, minimizing autofluorescence interference in biological samples. Tetra-sulfo-Cy7 DBCO is ideal for use in various imaging techniques, where its long-wavelength emission is optimized for detection by advanced imaging systems.

Cat. No.

B11381

CAS No.

2516243-92-6

UBQ-3 NHS ester

UBQ-3 NHS Ester is a fluorescent dye characterized by its terminal N-hydroxysuccinimide (NHS) ester group. The compound exhibits a broad emission spectrum ranging from 620 to 730 nm, making it an excellent acceptor for fluorescence resonance energy transfer (FRET) applications when paired with far-red to near-infrared emitting dyes, such as Cy5 and Alexa Fluor variants. This NHS ester can effectively label primary amines (-NH2) found on proteins, amine-modified oligonucleotides, and other amine-containing biomolecules, facilitating various biochemical and molecular biology research applications.