Dopamine Receptors

Cat. No.

A97071

CAS No.

3138-90-7

1-Benzyl-3-methylpiperazine

Synonyms: 3-Methyl-1-benzyl-piperazine

1-Benzyl-3-methylpiperazine is a piperazine derivative that primarily functions as a monoamine receptor ligand. It exhibits significant activity at various serotonin and dopamine receptors, making it a valuable compound for research in neuropharmacology. This reagent is often utilized in studies exploring the effects of psychoactive substances and the mechanisms underlying mood regulation.

Cat. No.

A97097

CAS No.

38063-96-6

MDBP hydrochloride

MDBP hydrochloride is a piperazine derivative that acts as a central nervous system modulator. It demonstrates significant biological activity by influencing serotonin and dopamine receptors, making it a valuable tool for neuroscience research. This compound is useful for investigating psychiatric disorders and exploring the pharmacological effects of piperazine analogs.

Cat. No.

A97171

CAS No.

71676-01-2

Amisulpride N-oxide

Amisulpride N-oxide is a photodegradation product of Amisulpride, which acts as a dopamine D2/D3 receptor antagonist. This compound may be relevant for studies investigating the stability and degradation pathways of Amisulpride under light exposure. Its characterization can aid researchers in understanding the pharmacokinetics and metabolic processes associated with dopamine receptor modulation.

Cat. No.

A97185

CAS No.

2640680-83-5

1-(4-Trifluoromethylphenyl)piperazine hydrochloride

1-(4-Trifluoromethylphenyl)piperazine hydrochloride is a piperazine derivative that primarily targets serotonin receptors, particularly the 5-HT2A subtype. It exhibits significant biological activity as a psychotropic agent, making it useful in studies related to neuropharmacology and mental health disorders. This compound serves as a valuable tool in research exploring the modulation of serotonin signaling and its effects on behavior and cognition.

Cat. No.

A97398

CAS No.

40160-26-7

1-(2-Trifluoromethylphenyl)piperazine hydrochloride

1-(2-Trifluoromethylphenyl)piperazine hydrochloride is a piperazine derivative that functions as a receptor modulator. This compound demonstrates significant biological activity in neurological research and is often utilized in studies related to central nervous system disorders. It serves as a valuable tool for investigating neurotransmitter pathways and receptor interactions in various biological systems.

Cat. No.

A97421

CAS No.

84477-71-4

2-BZP

Synonyms: 2-Benzylpiperazin

2-BZP is a piperazine compound that functions as a central nervous system stimulant by targeting serotonin and dopamine receptors. Its primary biological activity includes modulation of neurotransmitter release, making it useful in research related to neuropharmacology and behavioral studies. 2-BZP serves as a valuable tool for elucidating the mechanisms of psychostimulant effects and exploring potential therapeutic applications.

Cat. No.

A97457

CAS No.

95884-48-3

1-(3-Chloro-4-fluorophenyl)piperazine hydrochloride

1-(3-Chloro-4-fluorophenyl)piperazine hydrochloride is a piperazine derivative that acts as a potent and selective modulator of various neurotransmitter systems. This compound is primarily utilized in neuroscience research to investigate its effects on serotonin and dopamine receptors, contributing to the understanding of mood disorders and psychotropic drug action. Its unique chemical structure makes it valuable for studies related to pharmacology and medicinal chemistry.

Cat. No.

A97867

CAS No.

849903-79-3

Paliperidone impurity 3

Paliperidone impurity 3 is a known impurity of the antipsychotic agent Paliperidone, which primarily targets dopamine receptors. This compound is utilized in pharmaceutical research for quality control and to assess the purity of Paliperidone formulations. It serves as a crucial reference standard in the development and validation of analytical methods, ensuring compliance with regulatory standards in drug production.

Cat. No.

A98464

CAS No.

28059-64-5

2-Benzylaniline

Synonyms: 2-Aminodiphenylmethane

2-Benzylaniline is an intermediate compound that serves as a precursor in the synthesis of Compound 15. This derivative exhibits affinity for the D3 dopamine receptor, with a Ki value of 4654 nM. 2-Benzylaniline is valuable in research related to mental disorders, enabling the exploration of therapeutic targets within neuropharmacology.

Cat. No.

A98579

CAS No.

4640-41-9

Brexpiprazole impurity 1

Brexpiprazole impurity 1 is a chemical impurity related to the atypical antipsychotic Brexpiprazole, which primarily targets serotonin and dopamine receptors. This impurity can be utilized in the assessment of drug quality and to investigate the stability and degradation pathways of Brexpiprazole. Its presence may influence the pharmacological profile and safety evaluations in related research applications.

Cat. No.

A99383

CAS No.

1797131-21-5

Ropinirole impurity 1

Ropinirole impurity 1 is a structural impurity derived from Ropinirole, a selective dopamine agonist primarily targeting D2 dopamine receptors. This reagent is crucial for analytical and quality control applications, serving as a reference standard for assessing the purity and quality of Ropinirole formulations. Its characterization aids in the understanding of processing variability and ensures compliance with regulatory standards in pharmaceutical development.

Cat. No.

B10149

CAS No.

1246815-83-7

Pramipexole impurity 1

Synonyms: 2-N-Propyl pramipexole

Pramipexole impurity 1 (2-N-Propyl pramipexole) is a chemical impurity associated with the drug Pramipexole, which targets dopamine receptors. This impurity is essential for quality control and validation studies in pharmaceutical research, ensuring the purity and safety of drug formulations. It serves as a reference compound in analytical chemistry and can facilitate the investigation of drug metabolism and pharmacokinetics.

Cat. No.

B10300

CAS No.

954117-22-7

Ropinirole impurity 2

Ropinirole impurity 2 is a chemical impurity associated with the synthesis of Ropinirole, a dopamine receptor agonist. This compound can be utilized for analytical purposes in the assessment of drug purity and quality control in pharmaceutical research. Its presence is significant for the evaluation of Ropinirole formulations and may impact the overall efficacy and safety profile of the drug.

Cat. No.

B10463

CAS No.

920755-10-8

Ropinirole impurity 5

Ropinirole impurity 5 is a chemical impurity associated with Ropinirole, a dopamine agonist primarily targeting the D2 and D3 dopamine receptors. This impurity is important for analytical and quality control purposes in pharmaceutical research and development. Its identification and quantification are crucial for ensuring the purity and safety of Ropinirole formulations.

Cat. No.

B10695

CAS No.

1027600-42-5

Ropinirole impurity 3

Ropinirole impurity 3 is a characterized impurity associated with the dopamine receptor agonist Ropinirole. This compound is crucial for assessing the purity and quality of Ropinirole in pharmaceutical formulations. It aids in the development and validation of analytical methods required for regulatory compliance in drug manufacturing.

Cat. No.

B10727

CAS No.

76013-31-5

Fluphenazine decanoate impurity 8

Fluphenazine decanoate impurity 8 is a known impurity associated with Fluphenazine decanoate, an antipsychotic medication primarily targeting dopamine receptors. This compound can be utilized in analytical research to evaluate the purity of pharmaceutical formulations and support drug development processes. Its presence may affect pharmacokinetics and pharmacodynamics, making it essential for quality control and safety assessments in therapeutic applications.

Cat. No.

B10842

CAS No.

851-68-3

(±)-Levomepromazine ((±)-Methotrimeprazine, dl-Methotrimeprazine)

Synonyms: (±)-Methotrimeprazine; dl-Methotrimeprazine

(±)-Levomepromazine is a racemic mixture primarily targeting dopamine receptors. It exhibits notable antipsychotic activity, making it relevant for research in psychiatry and neuropharmacology. Its effects on neurotransmitter pathways are valuable for studying various psychiatric disorders and the mechanisms of psychotropic agents.

Cat. No.

B10930

CAS No.

69367-51-7

(R)-5-OH-DPAT

Synonyms: (R)-5-Hydroxy-DPAT

(R)-5-OH-DPAT is a selective modulator of the dopamine D2 receptor, functioning as a weak antagonist. This compound has been shown to influence dopaminergic signaling and modulate behaviors related to sexual activity, particularly in male rats. Its role in research explores the complex interactions within dopaminergic pathways and may contribute to studies on neuropsychiatric disorders and sexual behavior modulation.

Cat. No.

B12381

CAS No.

1185177-12-1

7-Benzyloxy-N-des[[2-(2-hydroxy)ethoxy]ethyl] Quetiapine-d8

7-Benzyloxy-N-des[[2-(2-hydroxy)ethoxy]ethyl] Quetiapine-d8 is a deuterium-labeled derivative of Quetiapine, a psychopharmacological agent primarily targeting serotonin and dopamine receptors. This stable isotope is utilized in pharmacokinetic studies to accurately track drug metabolism and bioavailability. It serves as a valuable tool for researchers investigating the pharmacodynamics and pharmacogenomics of antipsychotic therapies.

Cat. No.

B12411

CAS No.

1216730-87-8

Chlorproethazine-d10 hydrochloride

Chlorproethazine-d10 hydrochloride is a deuterium-labeled derivative of Chlorproethazine hydrochloride, functioning as a stable isotope. This compound is primarily utilized in pharmacokinetic studies and drug metabolism research, allowing for enhanced tracking and quantification in biological systems. Its incorporation of deuterium facilitates improved analytical precision in investigations involving the pharmacodynamics of antagonists at dopamine receptors.

Cat. No.

B13165

CAS No.

1246820-80-3

rac-Rotigotine-d3 methyl ether

rac-Rotigotine-d3 methyl ether is a deuterium-labeled analogue of the dopamine agonist rotigotine, targeting dopamine D2 and D3 receptors. This stable isotope is primarily utilized in pharmacokinetic studies and metabolic research, enabling precise tracking of rotigotine's distribution and metabolism in biological systems. Its application enhances the understanding of dopamine receptor activity and drug interactions.

Cat. No.

B14283

CAS No.

76787-63-8

Apomorphine hydrochloride-d4

Synonyms: (-)-Apomorphine hydrochloride-d4

Apomorphine hydrochloride-d4 is a deuterium-labeled derivative of Apomorphine hydrochloride, designed as a stable isotope for metabolic studies. This compound serves as a valuable tool in pharmacokinetic and drug metabolism research, enabling precise tracking of Apomorphine in biological systems. Its application extends to studies on dopamine receptor modulation and related neurological pathways, facilitating a deeper understanding of dopaminergic signaling and its implications in various disorders.

Cat. No.

B14520

CAS No.

1217744-19-8

trans-Dihydro Tetrabenazine-d7

trans-Dihydro Tetrabenazine-d7 is a deuterium-labeled stable isotope of (2S,3S,11bS)-3-Isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol. It serves as a valuable tool for isotopic labeling in biochemical research. Its distinct mass characteristics facilitate studies on pharmacokinetics, metabolism, and drug interactions, particularly in the context of neuropharmacology and the investigation of dopamine receptors.

Cat. No.

B18219

CAS No.

1259305-29-7

Aripiprazole Lauroxil

Aripiprazole Lauroxil is a long-acting injectable antipsychotic targeting dopamine receptors D2 and D4. It is an N-acyloxymethyl proagent of Aripiprazole, which undergoes enzymatic cleavage by esterases in the body to yield N-hydroxymethyl aripiprazole and lauric acid, further converting to aripiprazole and formaldehyde. This compound exhibits therapeutic activity in the management of schizophrenia and is utilized in research related to psychotropic medications and long-term treatment strategies.

Cat. No.

B18274

CAS No.

1225-65-6

Prothipendyl hydrochloride

Prothipendyl hydrochloride is a tricyclic azaphenothiazine neuroleptic agent that primarily targets neurotransmitter pathways within the central nervous system. It exhibits sedative and psychomotor dampening effects, making it valuable for studying conditions related to psychomotor agitation, sleep disorders, and anxiety. Additionally, Prothipendyl hydrochloride serves as a substrate for various cytochrome P450 isozymes, including CYP1A2, CYP2D6, CYP2C19, and CYP3A4, providing insights into metabolic pathways involved in drug action and interaction.