ICMT | Adooq Bioscience

Cat. No.: A60954

CAS No.: 303728-92-9

ICMT-IN-49

ICMT-IN-49 is a potent inhibitor of Isoprenylcysteine Carboxyl Methyltransferase (ICMT), demonstrating an IC50 of 0.12 μM. This compound plays a critical role in modulating cellular processes by regulating protein methylation and is valuable in studies targeting protein function and signaling pathways. Research applications include investigations into cancer biology, neurodegenerative diseases, and other conditions where ICMT activity is implicated.

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Cat. No.: A60955

CAS No.: 1313602-67-3

ICMT-IN-42

ICMT-IN-42 is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), demonstrating an IC50 value of 0.054 μM. This compound is valuable for research into the role of ICMT in post-translational modifications and protein function regulation. It is suitable for studies investigating cancer biology, signal transduction, and therapeutic development targeting ICMT pathways.

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Cat. No.: A60956

CAS No.: 1313602-93-5

ICMT-IN-9

ICMT-IN-9 is an inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), with an IC50 of 0.16 μM. This compound selectively targets ICMT, playing a significant role in regulating post-translational modifications of proteins that are essential for various cellular processes. ICMT-IN-9 can be utilized in research applications focused on cancer biology, signal transduction, and the study of protein interactions influenced by methylation.

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Cat. No.: A60957

CAS No.: 1313602-73-1

ICMT-IN-3

ICMT-IN-3 is a potent inhibitor of Isoprenylcysteine Carboxyl Methyltransferase (ICMT) with an IC50 value of 0.015 μM. This compound is crucial for studying protein modification processes, particularly in the context of signal transduction and cellular regulation. It serves as a valuable tool for investigating the role of ICMT in various biological pathways and its potential implications in disease mechanisms.

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Cat. No.: A60958

CAS No.: 1313602-74-2

ICMT-IN-4

ICMT-IN-4 is a potent inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT), with an IC50 value of 0.27 μM. This compound plays a crucial role in the modulation of protein prenylation, impacting various cellular processes. It is valuable for research applications aimed at investigating the role of ICMT in signaling pathways and disease models related to cancer and other disorders.

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Cat. No.: A60959

CAS No.: 1313603-20-1

ICMT-IN-33

ICMT-IN-33 is a potent inhibitor of Isoprenylcysteine carboxyl methyltransferase (ICMT) with an IC50 value of 0.46 μM. This compound effectively disrupts the post-translational modification of proteins by inhibiting ICMT activity. It is invaluable for research applications focused on elucidating the role of ICMT in cellular signaling and protein function, as well as potential therapeutic interventions targeting ICMT-related pathways.

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Cat. No.: A60960

CAS No.: 68000-92-0

Farnesylcysteine

Farnesylcysteine (FC) is a competitive inhibitor of isoprenylcysteine carboxyl methyltransferase (ICMT). It has been shown to induce an abscisic acid (ABA) hypersensitive phenotype in Arabidopsis thaliana, highlighting its role in plant stress responses. This reagent is valuable for research applications focused on signaling pathways and mechanisms involving ICMT inhibition and ABA-related processes.

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5 mg

$160.00

10 mg

$260.00

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Cat. No.: A60961

CAS No.: 1313602-77-5

ICMT-IN-55

ICMT-IN-55 is a selective inhibitor of isoprenylcysteine carboxymethyltransferase (ICMT) with an IC50 of 90 nM. This compound plays a crucial role in inhibiting ICMT activity, leading to the disruption of protein processing involved in various cellular signaling pathways. ICMT-IN-55 is utilized in research focused on understanding the biological significance of protein lipidation and its implications in cancer and other diseases.

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Cat. No.: A60962

CAS No.: 1001438-81-8

Spermatinamine

Spermatinamine is a natural inhibitor of Isoprenylcysteine carboxyl methyltransferase (ICMT). This novel alkaloid, characterized by its bromotyrosyl-spermine-bromotyrosyl sequence, exhibits significant biological activity affecting protein prenylation. It is derived from the Australian sponge Pseudoceratina and is useful in research applications investigating the roles of ICMT and protein modification pathways in cellular processes.

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Cat. No.: A60963

CAS No.: 1443253-20-0

CAY10677

CAY10677 is a potent inhibitor of Isoprenylcysteine carboxyl methyltransferase (ICMT), a critical enzyme involved in post-translational modifications of proteins. This compound has demonstrated significant ability to inhibit cancer cell proliferation, making it a valuable tool for cancer research. Additionally, CAY10677 exhibits favorable PAMPA permeability, enhancing its applicability in cellular assays.

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Cat. No.: A60964

CAS No.: 1621536-10-4

UCM-13207

UCM-13207 is a selective inhibitor of Isoprenylcysteine Carboxyl Methyltransferase (ICMT) with potential applications in aging research. This compound has been shown to mitigate progeria-like characteristics and enhance the survival rate in LmnaG609G/G609G mice, serving as an effective tool in studying cellular aging processes and related disorders. Researchers can utilize UCM-13207 to explore therapeutic strategies for age-related diseases.

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1 mg

$85.00

5 mg

$215.00

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Cat. No.: A60965

CAS No.: 1244769-10-5

J1-1

J1-1 is an inhibitor of Isoprenylcysteine Carboxyl Methyltransferase (ICMT), with an IC50 of 1.0 μM. This compound demonstrates notable anticancer activity, making it a valuable tool for research into cancer biology. J1-1 can be utilized in studies focusing on protein modification and its implications in oncogenic signaling pathways.

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