All Dyes

Cat. No.

A24873

CAS No.

143413-85-8

Thiazole orange dimer YOYO 1

Synonyms: YOYO 1

Thiazole orange dimer YOYO 1 is a fluorescent dye that specifically targets DNA for staining applications. As a tetracationic homodimer of oxazole yellow, it exhibits minimal fluorescence in solution but significantly enhances its emission upon binding to double-stranded DNA via diintercalation, resulting in a fluorescence intensity increase of over 3200-fold. This remarkable amplification of fluorescence makes YOYO 1 an invaluable tool for various research applications, including nucleic acid quantification and visualization in molecular biology and genetic studies.

Cat. No.

A24879

CAS No.

1562-85-2

Gallocyanine chloride

Gallocyanine chloride is a DKK1 inhibitor that targets the DKK1/LRP6 interaction, exhibiting an IC50 of 6.38 μM. This compound is relevant for research into Alzheimer's disease and related neurodegenerative tauopathies, as it activates the Wnt signaling pathway and promotes β-catenin accumulation. Additionally, Gallocyanine chloride demonstrates anti-metastatic, anti-inflammatory, and anti-fibrotic properties, and can serve as a fluorescent probe for the detection of superoxide anion radicals.

Cat. No.

A24883

CAS No.

1420815-55-9

DFAME

DFAME is a red fluorophore with excitation and emission wavelengths of 508 nm and 641 nm, respectively. It selectively binds to dimeric fluorescent RNA aptamers derived from Beetroot and Corn, yielding complexes with dissociation constants of 460 nM and 3600 nM, respectively. These Beetroot-DFAME and Corn-DFAME complexes facilitate the assembly of RNA structures within living cells, making them valuable tools for studying RNA nanostructures. The application of DNA/RNA nanostructures holds significant promise in advancing research in cell and gene therapy.

Cat. No.

A24885

CAS No.

20666-12-0

Luminol sodium salt

Luminol sodium salt is a chemiluminescent compound that produces light at a maximum wavelength of 425 nm. This compound is widely utilized in forensic science as a sensitive indicator for the presence of blood stains, leveraging its unique ability to emit light in the presence of hemoglobin. Additionally, Luminol sodium salt has applications in environmental monitoring and biochemical assays, enhancing detection and analysis in various research fields.

Cat. No.

A24891

CAS No.

6358-69-6

Pyranine

Synonyms: HPTS; Solvent Green 7

Pyranine is a cell-impermeant, pH-sensitive fluorescent indicator that serves primarily as a pH monitor. This compound exhibits strong fluorescence and acts as a chemosensor for copper ions (Cu+), making it valuable for various biochemical applications. Pyranine is widely utilized as a biological stain, optical detecting reagent, and as a coloring agent in research environments, with an excitation/emission spectrum of 450/510 nm. Its ability to provide precise pH measurements enhances its utility in various experimental setups.

Cat. No.

A24892

CAS No.

1097709-31-3

Mag-Fluo-4 AM

Mag-Fluo-4 AM is a fluorescent calcium ion indicator that exhibits a high affinity for Ca²⁺. This compound enables the specific detection of intracellular calcium ions with exceptional sensitivity and minimal cytotoxicity. Upon entering the cell, it is hydrolyzed by intracellular esterases, allowing it to bind calcium ions and emit strong fluorescence. Mag-Fluo-4 AM is widely applicable in studies involving calcium signaling and cellular functions.

Cat. No.

A24893

CAS No.

69898-45-9

Ferrozine

Ferrozine is an iron dye reagent that specifically targets divalent iron ions (Fe2+). Upon reaction, it forms a stable magenta complex, which exhibits a maximum absorption peak at 562 nm. This property enables the use of Ferrozine in colorimetric assays for the quantitation of iron in biological samples, facilitating research in iron metabolism and cellular iron homeostasis.

Cat. No.

A24894

CAS No.

52698-84-7

Bathocuproine disulfonate disodium

Bathocuproine disulfonate disodium (BCS) is a highly sensitive colorimetric reagent utilized for the detection of copper ions in biochemical assays. This compound exhibits a bright yellow color and possesses strong absorbance at specific wavelengths, enabling the quantification of trace levels of copper. BCS is instrumental in studying copper's biological roles, as well as in environmental monitoring and water quality testing, where its sensitivity allows for the identification of copper pollution, even at minimal concentrations. Accurate measurement of copper is essential for understanding its physiological effects and ecological impacts.

Cat. No.

A24895

CAS No.

72-57-1

Trypan Blue

Synonyms: Direct Blue 14; Diphenyl Blue; Diamine Blue

Diphenyl Blue, also known as Trypan Blue, is a vital reference dye primarily used to assess cell membrane integrity and viability. It selectively stains dead or damaged cells blue, allowing for the identification of non-viable cells in various tissue and cell culture applications. Viable cells with intact membranes exclude the dye, while macrophages can phagocytize Diphenyl Blue, making it an effective living stain for studying these immune cells. This dye is essential for research involving cell viability assays and tissue analyses.

Cat. No.

A24896

CAS No.

2315-97-1

Lucigenin

Synonyms: NSC-151912; L-6868

Lucigenin is a chemiluminescence probe primarily utilized for the detection of the endogenous superoxide anion radical (O2-). This compound exhibits high sensitivity and can also function as a chloride indicator, as its fluorescence is quenched in the presence of chloride ions. With excitation and emission wavelengths of 455 nm and 505 nm, respectively, Lucigenin serves as a valuable tool in studies involving reactive oxygen species and chloride ion interactions.

Cat. No.

A24897

CAS No.

21658-70-8

BODIPY 505/515

BODIPY 505/515 is a lipophilic fluorescent dye with a strong ultraviolet absorption capacity and sharp fluorescence peak, offering a high quantum yield. This compound exhibits stability across various physiological conditions and is relatively insensitive to environmental polarity and pH. BODIPY 505/515 effectively penetrates cell membranes, allowing specific labeling of neutral lipids within lipid droplets in both live and fixed cells. It is ideal for applications in cellular imaging, studying lipid metabolism, and analyzing cellular lipid storage. Maximum excitation and emission wavelengths are 505 nm and 515 nm, respectively.

Cat. No.

A24898

CAS No.

2044-85-1

2′,7′-Dichlorofluorescein diacetate

Synonyms: DCFH2-DA

2′,7′-Dichlorofluorescein diacetate (DCFH2-DA) is a cell-permeable fluorescent probe utilized for the detection of reactive oxygen species (ROS). It becomes fluorescent upon cleavage by intracellular esterases and subsequent oxidation, allowing for the assessment of oxidative stress levels in biological systems. This reagent is essential for studies in toxicology and cellular signaling, enabling researchers to monitor and evaluate oxidative phenomena in various experimental contexts.

Cat. No.

A24899

CAS No.

2365532-64-3

Copper Fluor-4

Synonyms: CF4

Copper Fluor-4 (CF4) is a highly selective fluorescent probe for Cu+ ions, utilizing a rhodol dye scaffold. With a Kd value of 2.9×10−13 M, it demonstrates exceptional selectivity for copper over competing metal ions such as zinc and iron, as well as common cellular alkali and alkaline earth metals. Copper Fluor-4 remains stable within a physiologically relevant pH range of 6 to 8, making it suitable for various biological applications, including imaging and quantification of copper ions in live cells. Excitation occurs at 415 nm with emission at 660 nm.

Cat. No.

A24900

CAS No.

143-74-8

Phenol Red

Synonyms: Phenolsulfonephthalein

Phenol Red is a pH indicator dye that exhibits a notable color transition from pink to yellow in response to changes in acidity. This property makes it essential for applications in cell culture and biological research, where monitoring pH levels is crucial for maintaining optimal conditions for cell viability and function. Phenol Red is widely utilized in laboratory assays and as a diagnostic tool for evaluating the conditions of various biological systems.

Cat. No.

A24901

CAS No.

1392820-50-6

MitoPerOx

MitoPerOx is a fluorescent probe designed to detect lipid peroxidation specifically in mitochondria, utilizing BODIPY581/591 fluorophores. With its triphenylphosphine cation (TPP+), MitoPerOx selectively accumulates in mitochondria based on membrane potential, allowing for sensitive measurement of lipid peroxides within the inner mitochondrial membrane. The probe exhibits a ratiometric emission shift from 590 nm to 520 nm upon oxidation, facilitating accurate detection at an excitation wavelength of 488 nm. MitoPerOx is valuable for investigating oxidative stress-associated diseases, including aging, neurodegenerative disorders, and mitochondrial dysfunction.

Cat. No.

A24902

CAS No.

71206-95-6

Lucifer Yellow CH dipotassium salt

Lucifer Yellow CH dipotassium salt functions as a high-intensity fluorescent dye, primarily utilized for its ability to react with fatty aldehydes at room temperature. This probe is valuable in biological research for tracing neuronal branching, monitoring regeneration, and detecting gap junctions, as well as for selective ablation of cells following aldehyde fixation. It exhibits optimal excitation and emission wavelengths of 430 nm and 540 nm, respectively, making it an effective tool in various fluorescence microscopy applications.

Cat. No.

A24903

CAS No.

82-76-8

ANS

Synonyms: ANSA; 8-Anilino-1-naphthalenesulfonic acid

ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor of thyroxine binding globulin (TBG), exhibiting a Ki value of 2.09×10^6 M^-1. This compound is utilized in radioimmunoassays to enhance detection sensitivity by displacing bound triiodothyronine (T3) and facilitating its recognition by antibodies. Additionally, ANS serves as a fluorescent probe, selectively binding to hydrophobic regions of proteins, particularly membrane proteins, allowing for real-time monitoring of protein conformational dynamics through fluorescence changes. Its applications extend to biochemical research and the development of antibacterial materials.

Cat. No.

A24904

CAS No.

126208-12-6

Carboxy-SNARF 1 (5/6-mixture)

Synonyms: SNARF 1

Carboxy-SNARF 1 (5/6-mixture) is a pH-sensitive fluorescent probe utilized for the measurement of intracellular and environmental pH changes. It exhibits a significant emission shift from yellow-orange (Em: 580 nm) at acidic pH to deep red fluorescence (Em: 640 nm) in basic conditions, making it particularly useful for dynamic pH monitoring in biological systems. This probe is valuable in various research applications, including studying cellular metabolism, enzyme activity, and membrane potential.

Cat. No.

A24905

CAS No.

150206-05-6

5-Carboxyfluorescein diacetate N-succinimidyl ester

5-Carboxyfluorescein diacetate N-succinimidyl ester is a cell-permeable fluorescent dye with an excitation wavelength of 492 nm and an emission wavelength of 517 nm. It covalently labels intracellular proteins, enabling the tracking of lymphocyte migration and proliferation in biological research. This reagent is particularly useful for studying immune responses and cellular dynamics in various experimental settings.

Cat. No.

A24906

CAS No.

54078-29-4

1,8-Diazafluoren-9-one

Synonyms: DFO

1,8-Diazafluoren-9-one is a chemical reagent primarily utilized in forensic analysis for the detection of latent fingerprints on porous surfaces. This compound reacts with amino acids found in fingerprints, resulting in the formation of highly fluorescent derivatives, with an excitation/emission maximum of approximately 470/570 nm. Its applications extend to enhancing imaging techniques in forensic science, facilitating reliable identification in criminal investigations.

Cat. No.

A24907

CAS No.

121714-22-5

Fluo-3AM

Synonyms: Fluo-3-pentaacetoxymethyl ester

Fluo-3 AM is a fluorescent calcium indicator that effectively chelates Ca2+ ions with high affinity. It is designed for the sensitive detection of intracellular calcium fluctuations, making it a valuable tool for monitoring cellular calcium dynamics. Due to its low cytotoxicity and efficient cellular uptake facilitated by the acetoxymethyl ester moiety, Fluo-3 AM is cleaved intracellularly, allowing for sustained binding to calcium ions and robust fluorescence output. This compound is widely used in studies related to signal transduction, muscle contraction, and various calcium-dependent cellular processes.

Cat. No.

A24908

CAS No.

7240-37-1

7-Aminoactinomycin D

Synonyms: 7-AAD

7-Aminoactinomycin D (7-AAD) is a cell-impermeant fluorescent DNA stain that primarily targets and binds to GC-rich regions of DNA. This compound is often utilized in flow cytometry and fluorescence microscopy to assess cell viability and apoptosis. Additionally, 7-AAD exhibits antibacterial properties, expanding its utility in various biological research applications.

Cat. No.

A24909

CAS No.

4197-25-5

Sudan Black B

Sudan Black B is a fat-soluble diazo dye used primarily as a histochemical stain. This reagent effectively stains neutral triglycerides and lipids, making it a valuable tool in the identification and analysis of adipose tissues and lipid-containing structures in biological samples. Its applications extend to research in lipid metabolism, pathology, and histological studies.

Cat. No.

A24910

CAS No.

150849-52-8

WST-1

WST-1 is a water-soluble tetrazolium salt that serves as a reagent for cell proliferation assays. It selectively undergoes reduction by intracellular mitochondrial dehydrogenases, resulting in the production of a soluble formazan product detectable at 450 nm. This compound is utilized to assess cell viability and cytotoxicity, making it an essential tool in various biological and pharmacological research applications.

Cat. No.

A24911

CAS No.

133867-53-5

BODIPY FL C5-Ceramide

BODIPY FL C5-Ceramide is a Golgi-specific fluorescent dye that targets the Golgi apparatus for precise cellular visualization. This BODIPY-labeled ceramide derivative is synthesized in the endoplasmic reticulum and is effectively transported to the Golgi through ceramide transport proteins or vesicular mechanisms. With an excitation/emission wavelength of 505 nm/512 nm, it is suited for applications in cell biology and imaging studies, allowing researchers to observe and analyze cellular structures with enhanced clarity.