Coumarin Dyes

Cat. No.

A45033

CAS No.

20300-59-8

7-Methoxycoumarin-3-carboxylic acid

7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye that exhibits excitation at 355 nm and emission at 405 nm. This compound is utilized for peptide labeling, making it valuable in various biological research applications, including biochemical assays and imaging studies. Its fluorescence properties enhance visualization and tracking of peptides in cellular and molecular studies.

Cat. No.

A45035

CAS No.

19088-73-4

3-Cyanoumbelliferone

3-Cyanoumbelliferone functions as a fluorescent dye and molecular probe, offering high sensitivity for various biological applications. Additionally, it acts as a macrophage migration inhibitory factor (MIF) tautomerase inhibitor with a Ki value of 2.9 μM. This compound is valuable for studying MIF-related pathways and assessing its role in inflammation and immune responses.

Cat. No.

A45069

CAS No.

2488174-16-7

Coumarin-C2-TCO

Coumarin-C2-TCO is a fluorochrome dye that incorporates a TCO group, enabling it to participate in inverse electron demand Diels-Alder (iEDDA) reactions with tetrazine-tagged molecules. This reactivity allows for specific and efficient labeling in various biological applications, including live cell imaging and protein tagging. The versatility of Coumarin-C2-TCO makes it a valuable tool for studying dynamic cellular processes and enhancing fluorescent assay sensitivity.

Cat. No.

A45088

CAS No.

134471-24-2

7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester

7-Hydroxycoumarin-3-carboxylic acid N-succinimidyl ester is an amine-reactive derivative of 7-Hydroxycoumarin-3-carboxylic acid, serving as a fluorescent dye. This compound exhibits blue fluorescence, making it suitable for the labeling of proteins and nucleic acids in various biological research applications. Its ability to conjugate with amines facilitates its use in tracking and visualization studies in cellular and molecular biology.

Cat. No.

A45098

CAS No.

19063-57-1

7-Aminocoumarin

7-Aminocoumarin is a fluorescent dye known for its excellent optical brightening properties. It serves as a powerful fluorescent probe in various biological applications, enabling visualization and tracking of cellular components. Its strong emission characteristics make it suitable for use in fluorescence microscopy and other imaging techniques in chemical and biomedical research.

Cat. No.

A45100

CAS No.

55804-66-5

Coumarin 314

Coumarin 314 is a fluorescent dye that exhibits intense absorption in the visible spectrum, making it suitable for a variety of fluorescence-based applications. Its strong solvent dependence allows for flexibility in experimental conditions, enabling effective use in biological imaging, labeling, and tracking studies. Researchers can utilize Coumarin 314 to enhance signal detection in assays and visualize cellular processes with high specificity and sensitivity.

Cat. No.

A45106

CAS No.

76877-34-4

DCIA

DCIA is a fluorescent dye that features a coumarin fluorophore, enabling specific conjugation to free cysteines in proteins. This property makes DCIA a valuable tool for the study of protein localization and interactions. Its applications include protein labeling and tracking in various biological systems, aiding in the visualization and analysis of protein dynamics in research studies.

Cat. No.

A45134

CAS No.

15991-13-6

Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate

Methyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate acts as a fluorescent dye through its unique coumarin structure. This compound is primarily utilized in the development of switchable fluorescent substrates, facilitating the detection of bacterial enzymes. Its properties make it a valuable tool for applications in biochemical assays and fluorescent imaging in research settings.

Cat. No.

A45145

CAS No.

928760-60-5

SNAP-430

SNAP-430 is a fluorescent probe labeled with (diethylamino) coumarin, designed for use with the SNAP-tag technology. This reagent facilitates the development of SNAP-tag fusion proteins in living cells, on cell surfaces, or in vitro, enabling real-time monitoring of protein dynamics and localization. Its application is crucial for studies involving protein interactions, gene expression, and cellular imaging.

Cat. No.

A45200

CAS No.

207673-94-7

7-Amino-4-methylcoumarin hydrogensulfate

Synonyms: Coumarin 120 hydrogensulfate; AMC hydrogensulfate

7-Amino-4-methylcoumarin hydrogensulfate is a multifunctional fluorescent dye characterized by its ability to readily bind to biomolecules. This compound is widely utilized in biological research for observing and analyzing cellular structures, tracking biomolecular interactions, and evaluating cell functions. Its versatile applications extend from basic scientific investigations to clinical diagnostics, as well as in emerging sectors such as functional textiles and dye-sensitized solar cells.

Cat. No.

A45242

CAS No.

160291-54-3

7-Diethylamino-3-N-(4-maleimidopropyl)carbamoylcoumarin

7-Diethylamino-3-N-(4-maleimidopropyl)carbamoylcoumarin is a multifunctional fluorescent dye designed for biological applications. This compound enables researchers to visualize and analyze cellular structures, track biomolecules, and assess cell functions. Its properties make it suitable for distinguishing cell types, detecting biomolecules, and studying tissue pathology, as well as applications in diagnostics and microbiology. Additionally, this dye can be utilized in various industries including textile processing, food pigments, and dye-sensitized solar cells.

Cat. No.

A45244

CAS No.

88404-26-6

6,7-Dimethoxy-4-coumarinylacetic acid

Synonyms: 2-(6,7-Dimethoxy-2-oxo-2H-chromen-4-yl)acetic acid

6,7-Dimethoxy-4-coumarinylacetic acid is a multifunctional dye with applications in biological research. This compound enables the visualization and analysis of cellular structures, tracking of biomolecules, and evaluation of cell functions. It is valuable for distinguishing cell types, detecting specific biomolecules, studying tissue pathology, and monitoring microorganisms. In addition to its biological research uses, this dye finds applications in industries such as textile manufacturing, food pigmentation, and dye-sensitized solar cells.

Cat. No.

A45246

CAS No.

203256-20-6

4-(7-Diethylaminocoumarin-3-yl)benzoyl cyanide

Synonyms: DACB-CN

4-(7-Diethylaminocoumarin-3-yl)benzoyl cyanide (DACB-CN) is a multifunctional dye that primarily targets molecular structures in biological systems. It exhibits key properties for visualizing and analyzing cell components, tracking biomolecules, and distinguishing various cell types. DACB-CN is suitable for applications in basic research, clinical diagnostics, tissue pathology studies, and microbial monitoring. Additionally, its versatility extends to fields such as functional textiles and dye-sensitized solar cells.

Cat. No.

A45294

CAS No.

946123-12-2

Coumarin 343 X NHS ester

Synonyms: Coumarin 343-aminohexanoic acid-NHS ester

Coumarin 343 X NHS ester is a fluorochrome dye that acts as a hydrophilic fluorescent probe. It is particularly useful in microfluidic applications, enabling the visualization of biological processes through its fluorescent properties. This reagent can be employed in various research fields, including cell imaging and fluorescence-based assays. The NHS ester functional group facilitates covalent labeling of amino groups in biomolecules, enhancing its utility in chemical biology and bioconjugation studies.

Cat. No.

A45295

CAS No.

2488319-02-2

Coumarin-PEG3-TCO

Coumarin-PEG3-TCO is a fluorochrome dye that incorporates three PEG units to enhance solubility and stability. Its TCO group facilitates an inverse electron demand Diels-Alder reaction (iEDDA) with tetrazine-bearing molecules, making it ideal for bioorthogonal labeling applications. This reagent is particularly useful in fluorescence microscopy and tracking cellular processes in live cells.

Cat. No.

A45296

CAS No.

2488174-19-0

Coumarin-PEG2-TCO

Coumarin-PEG2-TCO is a fluorescent dye that features a coumarin backbone modified with two PEG units. It utilizes a trans-cyclooctene (TCO) group to engage in an inverse electron demand Diels-Alder (iEDDA) reaction with tetrazine-containing compounds. This compound is valuable in biological imaging applications and has potential uses in the development of targeted fluorescent probes for live-cell imaging and other bioconjugation strategies.

Cat. No.

A45421

CAS No.

6950-82-9

7-Hydroxycoumarin-4-acetic acid

7-Hydroxycoumarin-4-acetic acid serves as a pH-indicator dye that exhibits fluorescence changes in response to pH variations. This compound is covalently attached to bovine serum albumin (BSA) at reactive amino group positions, allowing for enhanced stability and utility in biological systems. With an absorption maximum at 326 nm, it is applicable in studies requiring precise pH measurement and monitoring in various biochemical assays.

Cat. No.

A45425

CAS No.

87-05-8

7-Ethoxy-4-methylcoumarin

7-Ethoxy-4-methylcoumarin acts as a substrate probe for mammalian cytochrome P450 enzymes, specifically targeting CYP1A1, CYP2B4, and CYP2B6. This coumarin derivative is widely used in research to study enzymatic activity and metabolic pathways involving these cytochrome P450 isoforms. Its ability to provide insights into drug metabolism and toxicity makes it a valuable tool in pharmacological and toxicological studies.

Cat. No.

A45457

CAS No.

2747-04-8

7-Acetoxy-4-bromomethylcoumarin

7-Acetoxy-4-bromomethylcoumarin serves as a fluorescent dye primarily targeting fatty acids. This compound facilitates the detection and visualization of fatty acid metabolism and distribution in biological samples. Its fluorescent properties make it a valuable tool for researchers investigating lipid biology and cellular processes involving fatty acid signaling.

Cat. No.

A45468

CAS No.

314744-06-4

6,7-Diethoxy-4-methylcoumarin

6,7-Diethoxy-4-methylcoumarin is a fluorogenic substrate utilized for studying enzymatic activity. This compound exhibits fluorescent properties upon enzymatic conversion, making it useful in the detection and quantification of various enzymes in biological samples. Its application extends to areas such as drug metabolism studies and biological research involving Cordyceps militaris metabolites.

Cat. No.

A45474

CAS No.

26078-25-1

4,6-Dimethyl-7-ethylaminocoumarin

4,6-Dimethyl-7-ethylaminocoumarin is a fluorescent dye with applications in both pulse and continuous operation laser systems. This compound exhibits strong fluorescence properties, making it suitable for various biological imaging and analytical techniques. Its stability and efficiency make it an ideal choice for research involving fluorescence microscopy and spectroscopy.

Cat. No.

A48520

CAS No.

117756-27-1

Succinimide-AFK-AMC acetate

Succinimide-AFK-AMC acetate is a fluorescent substrate that targets Pseudomonas aeruginosa protease activity. This compound is utilized as a biomarker for identifying and quantifying protease production in cultured reference strains. It is particularly valuable for research on bacterial virulence and pathogenesis, enabling detailed study of protease-related mechanisms in infection models.

Cat. No.

A49508

CAS No.

97792-39-7

Z-Gly-Gly-Leu-AMC

Z-Gly-Gly-Leu-AMC is a selective substrate for ClpP1 and ClpP2 proteolytic activity. This compound is utilized to monitor and quantify the enzymatic activity of ClpP in conjunction with the activating peptide Z-Leu-Leu. Its application is crucial for research focused on protease activity, protein degradation pathways, and associated cellular processes.

Cat. No.

A52222

CAS No.

156192-32-4

Z-Leu-Arg-AMC

Z-Leu-Arg-AMC is a substrate specifically designed for the cysteine proteinase trypanopain-Tb derived from Trypanosoma brucei brucei. This 4-methylcoumarinyl-7-amide (Amc) leucine derivative features a carboxybenzoyl (Z) moiety, allowing for effective cleavage and fluorescence release. Its application in studying cysteine proteases makes it a valuable tool in proteomics and enzymology research, particularly in exploring the role of trypanopain in parasitic diseases.

Cat. No.

A69435

CAS No.

66642-36-2

L-Pyroglutamic acid 7-amido-4-methylcoumarin

L-Pyroglutamic acid 7-amido-4-methylcoumarin serves as a fluorogenic substrate for pyroglutamate aminopeptidase 1 (PGP-1). This compound exhibits biological activity by enabling the detection of PGP-1 enzymatic activity through fluorescence development. It is primarily utilized in biochemical assays for characterizing the enzyme's function and studying related pathways in research applications.