Angiotensin Receptors

Sparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively.

AVE 0991 is a nonpeptide and orally active angiotensin-(1-7) receptor agonist with an IC50 of 21 nM.

CGP48369 is a nonpeptidic angiotensin II receptor antagonist, used for anti-hypertensive research.

ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.

L162389 is a potent antagonist of angiotensin AT1 receptor with Ki of 28 nM.

Angiotensin III is an angiotensin 1 (AT1) and AT2 receptor agonist.

Apelin agonist 1 is an oral selective apelin agonist AM-2995, a agonist of the APJ (APLNR, angiotensin receptor like-1) receptor, may be used in the treatment of cardiovascular conditions.

Pratosartan is a selective angiotensin II receptor antagonist.

1H-1-Ethyl-d5 Candesartan is a deuterium-labeled derivative of 1H-1-Ethyl Candesartan, primarily utilized as a stable isotope. This compound is valuable in pharmacokinetic studies, allowing for precise tracking of drug metabolism and distribution. It aids researchers in understanding the metabolic pathways and interactions of angiotensin receptor antagonists in cardiovascular studies.

(Asn1,Val5)-Angiotensin II is a potent vasoconstrictor that acts primarily through the angiotensin receptor pathway. This synthetic derivative of angiotensin II demonstrates enhanced cardiac activation properties and is utilized in various cardiovascular research applications. Its ability to modulate blood pressure and vascular tone makes it a valuable tool for studying cardiovascular physiology and related disorders.