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All Dyes is the single product list for the Fluorescent Dyes, Probes & Stains section. Many dyes here have no application or dye-family subcategory, so the list is the broadest way to browse the range. It suits searches by product name when the required dye is already known. Examples range from the near-infrared cyanine indocyanine green and the ratiometric calcium indicator Fura-2 pentapotassium to the nucleic acid stains Hoechst 33258 trihydrochloride and SYBR Green II. Classical stains such as hematoxylin, reactive labeling dyes and enzyme substrates are listed alongside them. For selection by task or by core structure, the parent Fluorescent Dyes, Probes & Stains page groups dyes by application and dye family.
5(6)-SFX, SE is a fluorescent dye designed for the labeling of primary amines and nascent proteins. Its high fluorescence intensity enables sensitive detection and visualization in various biological assays. This reagent is ideal for applications in proteomics, cell biology, and molecular imaging, facilitating the study of protein dynamics and interactions in live cells.
BADAN (6-Bromoacetyl-2-dimethylaminonaphthalene) is a polarity-sensitive fluorescent probe that detects changes in the microenvironment around biomolecules. Its unique fluorescence characteristics enable monitoring of intracellular processes, lipid membranes, and protein conformational changes. BADAN is widely utilized in studies involving cellular dynamics, drug interactions, and in the assessment of membrane fluidity, making it an essential tool in chemical and biological research.
Synonyms: R6G-SE
5-Carboxyrhodamine 6G succinimidyl ester is an amine-reactive fluorescent dye with a high quantum yield. It is commonly utilized in various biological research applications, including cellular imaging, protein labeling, and tracking biomolecular interactions. The dye facilitates the visualization of biological structures and processes due to its bright fluorescence, making it an essential tool for studies involving live cells and tissue samples.
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8-Azido-cAMP is a fluorescent analog of cyclic adenosine monophosphate (cAMP) that serves as a key tool for detecting cAMP levels in biological samples. This compound contains an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) as well as strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with alkyne groups, such as dibenzocyclooctyne (DBCO) or bicyclo[6.1.0]nonyne (BCN). Its unique properties make it a valuable reagent for studying cAMP signaling pathways and interactions in various biological contexts.
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Synonyms: HM-JF526 NHS
HM Janelia Fluor® 526, SE is a fluorogenic dye known for its spontaneously blinking yellow emission characteristics. This compound is particularly effective for single-molecule localization microscopy (SMLM), providing enhanced imaging capabilities without the need for short-wavelength activation light. Its performance in standard phosphate-buffered saline (pH 7.4) demonstrates robust stability and functionality, making it suitable for advanced biological imaging applications. The unique properties of HM Janelia Fluor® 526, SE facilitate precise tracking of biomolecules, thus contributing to enhanced resolution in live-cell imaging studies.
Synonyms: JF585; SE; NHS
Janelia Fluor® 585, SE is an orange fluorescent dye featuring an NHS ester, enabling efficient conjugation with primary amine groups for labeling applications. This compound is particularly suited for structured illumination microscopy (SIM) and stimulated emission depletion (STED) imaging. Additionally, Janelia Fluor 585, SE can be modified into a photoactivatable derivative, making it valuable for single-molecule localization microscopy (SMLM) experiments.
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Alkyne-probe 1 is a fluorescent probe designed for click chemistry applications. Featuring an alkyne group, this reagent is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its ability to facilitate efficient labeling makes it a valuable tool for studying biomolecular interactions and visualizing cellular processes in various research applications.
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Synonyms: Ocean Blue; SE
PB succiniMidyl ester is a fluorescent dye characterized by excitation and emission wavelengths of approximately 405 nm and 455 nm, respectively. This compound exhibits strong fluorescent properties, making it suitable for various biological imaging applications. PB succiniMidyl ester can be utilized in experiments requiring high-resolution fluorescence detection, facilitating advancements in cellular and molecular biology studies.
TFAX 488,SE dilithium is a green fluorescent dye characterized by its pH insensitivity across a wide range (pH 4-10). This dye forms exceptionally bright, photostable conjugates with proteins and antibodies, including goat anti-mouse IgG and streptavidin. It is ideal for various biological imaging and labeling applications, making it a valuable tool for researchers in the fields of cell biology and biochemistry.
TFAX 488, TFP is a green fluorescent dye that exhibits pH insensitivity across a broad pH range of 4 to 10. This compound produces exceptionally bright and photostable conjugates with proteins and antibodies, making it valuable for applications in immunofluorescence and flow cytometry. Its robust performance enables reliable visualization in various biological research settings.
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Synonyms: AFDye 568 NHS Ester
TFAX 568, SE is an orange fluorescent dye that is pH-insensitive across a broad range of pH 4 to 10. It produces exceptionally bright and photostable conjugates with proteins and antibodies, making it an invaluable tool for various applications in fluorescence microscopy and imaging. This dye is particularly useful for labeling goat anti-mouse IgG, facilitating enhanced visibility in cellular assays and biological studies.
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TFAX 594,SE is a red fluorescent dye known for its pH-insensitivity across a wide range of pH (4-10). This dye produces exceptionally bright and photostable conjugates with proteins or antibodies, including goat anti-mouse IgG. It is ideal for applications in cellular imaging and fluorescence-based assays, enhancing the sensitivity and clarity of experimental results.
NIR dye-1 is a near-infrared (NIR) fluorescent dye with significant absorption and emission properties in the NIR spectrum, featuring an optically tunable hydroxyl group. This compound is suitable for applications in biological imaging and diagnostics, enabling enhanced contrast and sensitivity in fluorescence-based assays. Its unique properties make it an invaluable tool for researchers studying cellular processes and molecular interactions in vivo.
DY-680-NHS ester is a hydrophilic fluorescent dye that reacts with amines to enable the conjugation with antibodies. It maintains a high dye-to-protein (D/P) ratio while minimizing fluorescence quenching and conjugate precipitation. This versatile dye is suitable for a range of applications, including Western blotting, microscopy, flow cytometry, and various cell-based assays, featuring an excitation wavelength of 690 nm and an emission wavelength of 709 nm.
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AF555 NHS is a red fluorescent dye that exhibits superior fluorescence characteristics and light stability. With an excitation wavelength of 556 nm and an emission wavelength of 571 nm, it is ideal for various applications, including protein labeling, antibody labeling, and cell imaging. This reagent enables robust visualization and tracking of biological samples in research settings.
Synonyms: CMFDA
Green CMFDA is a cell-permeable fluorescent probe that serves as an effective cell tracer. It is cleaved by non-specific esterases present in live cells, resulting in the generation of fluorescein, which emits fluorescence at 514 nm upon excitation at 485 nm. This property makes Green CMFDA valuable for various research applications, including cell tracking and monitoring cellular processes in live-cell imaging studies.
Synonyms: ICG-OSu
ICG NHS ester (ICG-OSu) is a near-infrared fluorescent dye that exhibits amine-reactive properties. This derivative of indocyanine green is primarily employed in the development of in vivo imaging probes, facilitating enhanced visualization in biological research. Its fluorescence allows for effective tracking of biological processes and distribution in live organisms, making it a valuable tool in diagnostic and therapeutic applications.
IR-1061 is a near-infrared fluorescent organic dye designed for in vivo bimodal imaging applications. This compound provides high sensitivity and specificity, facilitating the visualization of biological structures and processes in live organisms. Its spectral properties make it suitable for various imaging modalities, enhancing research in molecular biology and preclinical studies.
Synonyms: S01448
IR-1048 is a nitroreductase (NTR)-responsive near-infrared (NIR) fluorescence and photoacoustic imaging probe, as well as a photothermal agent. This compound features a nitroimidazole group, which upon catalytic reduction by NTR in hypoxic conditions, re-establishes strong NIR absorption and fluorescence emission in the NIR II window. The resulting photothermal effect allows for targeted imaging and photothermal ablation of tumor hypoxic regions. IR-1048 is primarily utilized in high-contrast NIR II/photoacoustic imaging and photothermal therapy research, focusing on the characterization and diagnosis of the tumor hypoxic microenvironment.
FD-1080 free acid is a near-infrared (NIR-II) fluorophore that exhibits excitation at 1064 nm and emission at 1080 nm. This compound is particularly suitable for in vivo imaging applications, offering enhanced imaging depth and reduced light scattering. Its unique optical properties make it an invaluable tool for biological research, particularly in studying complex biological systems and disease models.
ICG-amine is a near-infrared fluorescent probe that selectively binds to amino acid residues without the requirement for condensing agents. As a tricarbocyanine dye, it exhibits strong fluorescence properties, making it suitable for various biological imaging applications. This compound is ideal for studies involving protein labeling, cellular imaging, and localization of biomolecules in live cells.
Synonyms: DiA
4-Di-16-ASP is a lipophilic aminostyryl probe that serves as a green fluorescent membrane dye. Its broad emission spectrum allows for detection using green, orange, or red filters, making it versatile for various imaging applications. This compound is particularly effective for neuronal membrane tracing due to its rapid diffusion properties, outpacing traditional dyes such as DiO. It is suitable for studies focusing on membrane dynamics and cellular morphology.
ICG-SH is a negatively charged polymethylcyanine dye that serves as a fluorescent marker in various biological research applications. This compound exhibits strong fluorescence properties, making it suitable for live cell imaging and tracking cellular processes. Its unique characteristics facilitate studies in diagnostics and therapeutic development, particularly in the fields of oncology and in vivo imaging.
CH1055 is a near-infrared II (NIR-II) fluorescent dye that serves as a powerful probe for in vivo imaging applications. Its superior fluorescence characteristics make it ideal for conjugation with antibodies or ligands, enabling targeted imaging such as tumor visualization. CH1055 is essential for researchers seeking advanced imaging techniques in preclinical studies.
FD-1080 is a near-infrared II (NIR-II) fluorophore that exhibits excitation at 1064 nm and emission at 1080 nm. Its unique spectral properties make it suitable for in vivo imaging applications, providing enhanced tissue penetration and reduced autofluorescence interference. Researchers can utilize FD-1080 for advanced imaging studies in biological systems, facilitating the investigation of cellular and molecular processes in real-time.
