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All Dyes is the single product list for the Fluorescent Dyes, Probes & Stains section. Many dyes here have no application or dye-family subcategory, so the list is the broadest way to browse the range. It suits searches by product name when the required dye is already known. Examples range from the near-infrared cyanine indocyanine green and the ratiometric calcium indicator Fura-2 pentapotassium to the nucleic acid stains Hoechst 33258 trihydrochloride and SYBR Green II. Classical stains such as hematoxylin, reactive labeling dyes and enzyme substrates are listed alongside them. For selection by task or by core structure, the parent Fluorescent Dyes, Probes & Stains page groups dyes by application and dye family.
Ac-WLA-AMC is a β5-specific fluorogenic substrate designed for the 20S constitutive proteasome. Upon hydrolysis, it emits a fluorescent signal, enabling real-time monitoring of proteasome activity. This substrate is ideal for research applications involving proteasome function, regulation, and potential drug discovery targeting proteasome-related pathways.
DDAO is a red fluorescent probe designed for near-infrared (NIR) applications, featuring tunable excitation wavelengths ranging from 600 to 650 nm and an emission wavelength of 656 nm. This compound is effective for the detection of various enzyme activities, including β-galactosidase, sulfatase, protein phosphatase 2A, carboxylesterase 2, human albumin, and esterases. DDAO is a valuable tool for biological research and enzyme activity assays, facilitating sensitive detection and analysis in diverse experimental settings.
Ac-ANW-AMC is a fluorogenic substrate specifically designed for the immunoproteasome, targeting the β5i subunit. It exhibits fluorescent properties, allowing for the quantitative measurement of β5i activity with excitation at 345 nm and emission at 445 nm. This reagent is useful in research applications focused on proteasome dynamics and immune response mechanisms.
4-Methylumbelliferyl β-D-galactopyranoside is a sensitive fluorescent substrate specifically designed for the detection of β-galactosidase activity. Upon enzymatic cleavage, it yields a water-soluble blue fluorescent coumarin, facilitating quantification through fluoroenzymetric assays or fluorometric analysis. This reagent is widely utilized in various research applications, including enzyme activity assays and monitoring gene expression in cellular models.
C6 NBD Glucosylceramide is a fluorescent derivative of glucosylceramide that serves as a valuable tool for studying the metabolism and internalization of glucosylceramide. With excitation at 466 nm and emission at 535 nm, this compound enables researchers to monitor glucosylceramide dynamics in cellular environments. Additionally, it can be employed to assess the activity of glucosylceramide synthase, making it an essential reagent for investigations into glycolipid metabolism and related cellular processes.
Synonyms: 1,5-EDANS
EDANS (1,5-EDANS) is a quenched fluorogenic substrate designed for the assessment of retroviral protease activity through resonance energy transfer (RET). This compound enables sensitive detection and quantification of protease activity, facilitating applications in virology and drug development. Its innovative design allows for an effective evaluation of protease inhibitors and contributes to understanding viral replication mechanisms.
Synonyms: Leu-AMC hydrochloride
L-Leucine-7-amido-4-methylcoumarin hydrochloride is a fluorogenic substrate specifically designed for leucine aminopeptidase 3 (LAP3). This substrate exhibits strong fluorescent properties, enabling sensitive detection of LAP3 enzymatic activity. It is suitable for use in in vitro assays aimed at investigating LAP3 function and potential inhibition, making it a valuable tool for biochemical and pharmacological research.
4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside functions as a fluorogenic substrate specifically for N-acetyl-β-D-glucosaminidase. This compound releases a fluorescent signal upon enzymatic cleavage, enabling sensitive detection and quantification of enzymatic activity. It is widely utilized in biochemical assays to study enzyme kinetics, facilitate substrate specificity analysis, and explore metabolic pathways involving glycosaminoglycans.
4-Methylumbelliferyl oleate is a fluorogenic substrate specifically designed for the activity detection of acid and alkaline lipases. Upon cleavage by lipases, it releases 4-Methylumbelliferyl, which can be detected via fluorescence with excitation and emission wavelengths of 320 nm and 450 nm, respectively. This compound is valuable for studying lipase activity in various biological contexts, including enzyme kinetics and metabolic research.
β-Ala-Lys(AMCA) is a multifunctional fluorescent dye that targets biomolecular interactions and cellular structures. It exhibits strong fluorescence, making it an invaluable tool for visualizing and analyzing cell morphology, tracking biomolecules, and distinguishing various cell types. β-Ala-Lys(AMCA) is applicable in a wide range of biological research, including cellular assays, tissue pathology studies, and microbial monitoring, as well as in emerging applications such as functional textiles and photonic devices.
BZiPAR is a fluorescent probe designed for the detection of trypsin activity. Upon cleavage by trypsin, BZiPAR exhibits enhanced fluorescence, making it a valuable tool for monitoring protease activity in biochemical assays. Its use in various research applications facilitates the study of proteolytic processes and enzyme kinetics, contributing to advancements in proteomics and related fields.
Resorufin butyrate is a fluorogenic substrate primarily utilized for the detection of triglyceride lipases and cholinesterase. With excitation at 570 nm and emission at 580 nm, this compound facilitates sensitive fluorescence-based assays. It is particularly valuable in biochemical studies focusing on lipid metabolism and enzyme activity.
QTZ is a bioluminescence agent designed for in vivo imaging applications. This compound features red-shifted emission properties along with minimal background interference, enhancing the clarity of imaging results. QTZ is a coelenterazine analog, distinguished by a 4-quinolinyl substitution at the C8 position of the imidazopyrazinone core, making it a valuable tool for researchers in the field of bioluminescent imaging.
5(6)-Carboxy-2',7'-dichlorofluorescein is a sensitive fluorescent probe with dual-targeting capabilities for studying fluorescein transport mechanisms. It demonstrates excellent properties for use in MRP2 vesicular transport assays, facilitating the assessment of drug transport and cellular efflux pathways. This compound is valuable for researchers investigating multidrug resistance and transporter function in various biological systems.
Synonyms: 3-Benzothiazole-daphnetin
3-BTD (3-Benzothiazole-daphnetin) is a two-photon fluorescence probe targeting Catechol-O-methyltransferase (COMT). It exhibits key biological activity by enabling the detection of endogenous COMT in living cells and tissue sections, making it a valuable tool for biological imaging applications. This compound aids in understanding the role of COMT in various physiological and pathological processes.
Oxazine 170 perchlorate is a laser dye that operates primarily through light absorption and fluorescence emission. It features a broad excitation spectrum ranging from 300 to 550 nm, effectively absorbing light above 550 nm and emitting fluorescence at approximately 645 nm. This compound is valuable for applications in fluorescence microscopy and other optical imaging techniques, enhancing the capabilities of various research studies in biological and material sciences.
4-Methylumbelliferyl palmitate is a fluorogenic substrate specifically designed to measure acid lipase activity in human leukocytes. Its fluorescence is significantly influenced by pH and solvent conditions, exhibiting strong emission at 445 nm in near-neutral aqueous solutions and enhanced fluorescence at 445 nm in weak alkaline environments. This compound is valuable for research applications focusing on lipid metabolism and enzymatic activity assays.
Z-Arg-AMC hydrochloride is a fluorogenic substrate specifically designed for the activity assays of trypsin and papain. This compound enables the monitoring of protease activity through fluorescence, with excitation and emission wavelengths at 355 nm and 460 nm, respectively. It is widely utilized in biochemical research to study proteolytic enzymes and their roles in various biological processes.
X-Gluc cyclohexanamine is a dye reagent specifically designed for the detection of β-glucuronidase (GUS), an enzyme commonly produced by E. coli. This compound is utilized to identify E. coli contamination in various samples, including food, water, and urine, serving as a specific indicator for GUS activity. Additionally, X-Gluc cyclohexanamine is applied in molecular biology studies to label and visualize the expression of target genes, producing a blue reaction upon interaction with the GUS gene.
Mu-6S-Palm-β-Glc is a fluorogenic substrate specifically designed for palmitoyl-protein thioesterase (PPT). This compound exhibits key biological activity suitable for investigating palmitoylation processes and can be utilized in research related to neuronal ceroid lipofuscin disease in infants. Its fluorescent properties make it an essential tool for studying protein modifications and their implications in neurodegenerative disorders.
Msr-blue is a novel turn-on fluorescent probe specifically designed to detect methionine sulfoxide reductase (Msr) activity. This probe exhibits a fluorescence increase of over 100-fold, enabling sensitive monitoring of enzyme activity in live cells with excitation at 340 nm and emission at 440 nm. Its application includes studying oxidative stress and redox signaling pathways in various biological contexts.
Synonyms: MFC
7-Methoxy-4-(trifluoromethyl)coumarin is a fluorescent substrate that serves as an effective tool for assessing cytochrome P450 enzyme activity. This compound enables the quantification of CYP activity, facilitating studies in drug metabolism and toxicology research. Its fluorescent properties make it suitable for various bioanalytical applications, providing valuable insights into pharmacokinetics and enzymatic functions.
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium is a fluorescent dye primarily targeting galactose-6-sulphate sulphatase. This compound is utilized in the diagnosis of mucopolysaccharidosis IV A by enabling the detection of enzymatic activity associated with this disorder. Its fluorescence facilitates quantitative analysis and biochemical research in cellular and tissue samples related to lysosomal storage diseases.
4-(Trifluoromethyl)umbelliferone is a fluorescent probe that selectively targets rat hepatic cytochrome P450 enzymes. This compound exhibits significant fluorescence enhancement upon metabolism, making it a valuable tool for studying enzyme activity and characterization in hepatic systems. Its applications include drug metabolism research and the investigation of cytochrome P450 enzyme kinetics.
Coumberol is a fluorescent substrate that specifically targets the AKR1C3 enzyme. This compound serves as a valuable tool for investigating the enzymatic activity of AKR1C3 in various biological contexts. It is particularly useful in research applications focused on metabolic pathways and disease mechanisms where AKR1C3 plays a critical role.
