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All Dyes is the single product list for the Fluorescent Dyes, Probes & Stains section. Many dyes here have no application or dye-family subcategory, so the list is the broadest way to browse the range. It suits searches by product name when the required dye is already known. Examples range from the near-infrared cyanine indocyanine green and the ratiometric calcium indicator Fura-2 pentapotassium to the nucleic acid stains Hoechst 33258 trihydrochloride and SYBR Green II. Classical stains such as hematoxylin, reactive labeling dyes and enzyme substrates are listed alongside them. For selection by task or by core structure, the parent Fluorescent Dyes, Probes & Stains page groups dyes by application and dye family.
HITCI is a positively charged indocarbocyanine dye primarily utilized as a laser dye in the near-infrared (NIR) spectrum. Its unique properties make it suitable for applications in fluorescence imaging and biological labeling. The dye demonstrates effective staining of cells and tissues, facilitating advanced research in biophysics and cellular biology.
IR-797 chloride is a near-infrared (NIR) dye with an absorption maximum of approximately 700 nm. This compound exhibits aggregation-induced emission (AIE) properties, making it useful for a variety of imaging applications. Additionally, IR-797 demonstrates cytotoxic effects, providing a valuable tool for research in cellular studies and phototherapy.
Near-IR fluorescent probe-1 is a multifunctional dye that targets biological imaging applications. This probe facilitates the observation and analysis of cellular structures, tracking of biomolecules, and assessment of cellular functions. Its capabilities extend to distinguishing cell types, detecting biomolecules, and studying tissue pathology, making it a valuable tool in both fundamental research and clinical diagnostics. Additionally, Near-IR fluorescent probe-1 finds applications in innovative fields such as functional textiles, food pigments, and dye-sensitized solar cells.
Disulfo-ICG carboxylic acid is a derivative of Indocyanine Green (ICG), a near-infrared (NIR) fluorescent dye. This compound functions as a fluorochrome dye, exhibiting strong fluorescent properties that make it suitable for various imaging applications, including live-cell imaging and in vivo diagnostics. Disulfo-ICG carboxylic acid is particularly beneficial in studies requiring enhanced biocompatibility and stability, facilitating advanced research in molecular biology and medical imaging.
Cypate is a near-infrared (NIR) fluorescent probe designed for in vivo tumor imaging. This cyanine dye exhibits strong fluorescence properties, enabling enhanced visualization of tumors in biological systems. Cypate is particularly useful in research applications involving cancer diagnostics and the monitoring of therapeutic efficacy. Its ability to penetrate deeply into biological tissues makes it a valuable tool for preclinical studies.
Synonyms: 3,3′-Diethylthiatricarbocyanine iodide
DTTCI (3,3′-Diethylthiatricarbocyanine iodide) functions as a sensitizing dye with a primary mechanism of enhancing infrared photographic sensitivity. This compound exhibits strong chiroptical properties, making it an effective reporter for assessing DNA helicity and sequence variations. Its sensitivity to structural changes in nucleic acids positions it as a valuable tool in molecular biology and biophysical studies.
Cryptocyanine is a fluorescent dye characterized by its strong luminescence properties. It is commonly used in various biological imaging applications, providing enhanced visualization of cellular structures and processes. This compound is particularly valuable in fluorescence microscopy and flow cytometry, enabling researchers to study biological phenomena with greater precision and clarity.
Fluorescent polyamine probe-1 is a linear polyamine compound designed for the investigation of polyamine transport mechanisms. This probe exhibits high cellular uptake efficiency, making it suitable for research into the delivery of compounds into cancer cells. Its fluorescent properties facilitate the visualization and study of cellular uptake dynamics in cancer research applications.
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NIR-641 N-succinimidyl ester is a fluorescent dye that operates through the formation of covalent bonds with amine-containing biomolecules. It exhibits strong near-infrared fluorescence, making it suitable for sensitive detection and imaging applications in biological research. This reagent is particularly valuable for labeling proteins and other cellular components, facilitating advanced studies in fluorescence microscopy and molecular imaging.
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Coumarin-PEG2-endoBCN is a fluorescent dye that incorporates a coumarin fluorophore, functioning as a versatile click chemistry reagent. It exhibits strong fluorescence properties, making it suitable for various biological imaging applications. This compound can be utilized in the labeling of biomolecules, facilitating studies in cellular dynamics and molecular interactions.
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IR 813 perchlorate is a near-infrared fluorescent dye that exhibits excitation at 815 nm and emission at 840 nm. This compound is primarily utilized for visualizing regional lymph nodes in murine models. Its unique optical properties make it an essential tool in studies of lymphatic function and metastatic behavior in cancer research.
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Fluorescent NIR 885 is a cyanine dye that exhibits near-infrared absorption, functioning as a photoprotective agent. Its primary mechanism involves effective light absorption in the near-infrared spectrum, providing protection against photodamage. This compound is valuable for research applications in photobiology and protective strategies in various biological systems, enabling the study of cellular responses to light exposure.
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Nile Blue Methacrylamide is a fluorescent pH densor derived from Nile Blue, designed for use in live bioimaging applications. Its distinct properties allow for simultaneous far-red and near-infrared imaging, facilitating enhanced visual resolution in biological samples. This reagent is particularly valuable in studies involving pH variations in cellular environments, contributing to advancements in cellular biology and imaging techniques.
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DMNPE-caged D-luciferin is a caged fluorescent dye that serves as a natural substrate for luciferase, an enzyme pivotal for monitoring cellular activity. Upon deprotection, this compound's luminescent properties allow for the emission of yellow-green light at a peak wavelength of approximately 530 nm, contingent on the presence of ATP. Its ability to permeate cell membranes enhances its utility in various biological research applications, including live-cell imaging and bioluminescence-based assays.
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Synonyms: 5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside
C12FDG (5-Dodecanoylaminofluorescein di-β-D-Galactopyranoside) serves as a lipophilic fluorescent substrate specifically designed for the detection of β-galactosidase activity. With enhanced sensitivity compared to traditional substrates, C12FDG allows for accurate assessment of β-galactosidase in various animal cell models, utilizing an excitation/emission wavelength of 488/523 nm. This compound is valuable for research applications focused on cellular processes involving β-galactosidase activity.
gGlu-2OMe SiR600 is a γ-glutamyltranspeptidase (GGT) responsive fluorescent probe that enables lesion visualization through fluorescence activation. Upon interaction with GGT, this probe is converted into a highly fluorescent form, overcoming initial quenching via a photoinduced electron transfer (PeT) mechanism. gGlu-2OMe SiR600 is particularly effective in distinguishing malignant breast cancer from benign breast fibroadenoma tissues, making it a valuable tool for research in oncology and cancer diagnostics.
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DCM-gal-CF is a fluorescent probe designed for the sensitive detection of β-galactosidase activity. It features a DCM fluorophore scaffold linked to a D-galactose recognition moiety, exhibiting weak fluorescence that significantly increases upon cleavage by β-galactosidase. This compound is valuable for applications in enzyme activity assays, enabling researchers to monitor β-galactosidase activity in various biological samples.
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4-MUNANA is a highly selective fluorescent substrate for influenza virus neuraminidase (NA), undergoing an irreversible enzymatic reaction that releases fluorescent 4-methylumbelliferone (4-MU). The fluorescence intensity of 4-MU provides a quantitative measure of NA activity, making 4-MUNANA a valuable tool in influenza research. Applications include screening for neuraminidase inhibitors, creating new anti-influenza therapies, and investigating the infection mechanisms of influenza viruses.
Z-Gly-Pro-AMC is a fluorogenic substrate specifically targeted for prolyl endopeptidase. Upon hydrolysis, it releases the highly fluorescent compound 7-Amino-4-methylcoumarin, which exhibits excitation and emission maxima at 380 nm and 465 nm, respectively. This substrate is primarily utilized in enzymatic assays and studies involving prolyl endopeptidase activity, making it valuable for research in enzyme kinetics and related fields.
Ac-DEVD-AFC is a fluorogenic substrate specifically designed for the detection of caspase-3 activity. Upon cleavage by caspase-3, it releases a fluorescent signal, enabling real-time monitoring of apoptosis. This reagent is widely used in cell biology research to evaluate programmed cell death and assess therapeutic effectiveness in various experimental settings.
Gly-Pro-AMC hydrobromide is a fluorescent dye designed for the specific detection of dipeptidyl peptidase IV (DPP-IV) activity. This substrate enables sensitive fluorescence measurements ideal for studying enzyme kinetics and activity in various biological samples. It serves as a valuable tool for researchers investigating DPP-IV's role in metabolic processes and its implications in conditions such as diabetes and obesity.
Boc-Val-Pro-Arg-AMC hydrochloride is a fluorogenic substrate specifically designed for the quantitative assessment of trypsin-like serine protease activity. It exhibits high sensitivity, enabling researchers to accurately measure the enzymatic activity of serine proteases in various biological samples. This reagent is useful in studies investigating protease function, substrate specificity, and screening of protease inhibitors.
Synonyms: DMMB
Dimethyl methylene blue zinc chloride double salt (DMMB) is a cationic fluorescent dye that primarily targets the active site of the PANI-Benz-Ag nanocomposite in the presence of endotoxins, enhancing fluorescence intensity upon release. It serves as an effective fluorescent probe for the detection of bacterial endotoxins, including those from E. coli. Additionally, DMMB is utilized for the quantification of sulfated glycosaminoglycans in various biological research applications.
Synonyms: MUG
4-Methylumbelliferyl-β-D-glucuronide hydrate is a fluorogenic substrate that emits fluorescence upon hydrolysis by β-glucuronidase (λex=362 nm, λem=445 nm). This reagent is primarily utilized for the detection of β-glucuronidase activity, making it valuable in various microbiological applications, including the quantification of Escherichia coli. Its sensitive fluorescence signal enhances detection capabilities in biochemical assays, contributing to effective research in enzymology and microbial studies.
Synonyms: Rhodamine 110 chloride; RH110
Rhodamine 110 is a fluorescent substrate designed for the detection and quantification of proteinases in both solution and living cells. This compound displays high sensitivity and selectivity, making it ideal for various protease activity assays. With an excitation wavelength of 498 nm and an emission wavelength of 521 nm, it is suitable for fluorescence microscopy and flow cytometry applications.
