All Dyes

Cat. No.

A44613

CAS No.

573-58-0

Congo Red

Congo Red is an azo dye that specifically binds to amyloid proteins. Its primary application is as a histological stain for the detection of amyloid deposits in tissue sections, facilitating the diagnosis of amyloidosis and related diseases. Additionally, Congo Red is utilized in various research studies to investigate protein aggregation and misfolding, making it a valuable reagent in both clinical and experimental settings.

Cat. No.

A44614

CAS No.

6104-58-1

Brilliant blue G-250

Brilliant Blue G-250 is a dye that functions as a P2×7 receptor (P2×7R) antagonist. It exhibits selective inhibition of P2×7R, leading to the inactivation of the NLRP3 inflammasome, which is crucial in inflammatory processes. This compound is widely utilized for protein visualization in SDS-PAGE, providing a straightforward staining method alongside high quantitation capabilities in the Bradford protein assay, where protein concentrations are assessed by measuring absorbance at 595 nm.

Cat. No.

A44615

CAS No.

115-39-9

Bromophenol blue

Bromophenol blue is an acid phthalein dye that functions as a pH indicator with a transition range of pH 3 to 4.6. Its utility in electrophoresis as a tracking dye enables the visualization of biomolecules during separation processes. Additionally, Bromophenol blue serves as a sensor for quantifying compounds such as ammonia, drugs, proteins, and amino acids, with significant absorbance observed at 610 nm upon protein binding.

Cat. No.

A44617

CAS No.

2411398-95-1

NTPAN-MI

NTPAN-MI is a fluorescent probe that operates through selective activation upon labeling unfolded proteins with exposed thiols. Functioning as a sensitive indicator of protein homeostasis, NTPAN-MI emits fluorescence at an excitation wavelength of 405 nm. This probe is invaluable for researchers investigating protein folding, stability, and the cellular stress response in various biological systems.

Cat. No.

A44619

CAS No.

6104-59-2

Brilliant Blue R250

Synonyms: Brilliant Blue R

Brilliant Blue R250 is an anionic dye primarily used for protein detection in SDS-PAGE gels. This dye effectively binds to proteins, providing clear visualization and enabling quantification of protein samples. It is widely utilized in biochemical research for analyzing protein purity and assessing protein molecular weight.

Cat. No.

A44620

CAS No.

130-22-3

Alizarin Red S sodium

Synonyms: ARS sodium

Alizarin Red S sodium is an anthraquinone-derived dye that specifically targets calcium deposits. This reagent forms coordination bonds with calcium ions, resulting in an orange-red fluorescence that can be detected under excitation at 500 nm and emission at 570 nm. Alizarin Red S sodium is widely used in research applications for screening calcium compounds in synovial fluid, detecting osteoblast differentiation, and visualizing bone structures in murine models.

Cat. No.

A44621

CAS No.

199293-83-9

NSP-SA-NHS

NSP-SA-NHS is a chemiluminescent acridinium ester used for the development of highly sensitive immunoassays. It facilitates rapid detection of target analytes, specifically in applications such as the assay of Bisphenol A (BPA). The compound's efficient labeling improves the sensitivity and specificity of immunoassays, making it suitable for various biomedical research applications.

Cat. No.

A44622

CAS No.

1937-37-7

Direct Black 38

Synonyms: Chlorazol Black E; Ferristatin II disodium; C.I. 30235

Direct Black 38 is a benzidine-based azo dye primarily utilized in textile dyeing applications. Its primary mechanism involves the degradation of azo bonds by microbial enzymes, particularly Enterococcus gallinarum azoreductase, leading to the release of benzidine and 4-aminobiphenyl. This compound is significant for studies in environmental toxicology, wastewater treatment, and carcinogenicity, although it is essential to note that its metabolite benzidine is classified as a human carcinogen.

Cat. No.

A44623

CAS No.

34487-61-1

Phenol Red sodium salt

Synonyms: Phenolsulfonephthalein sodium salt

Phenol Red sodium salt is a pH indicator dye with a primary role as an acid-base indicator. It exhibits a distinct color change from pink to yellow in response to shifts in pH, allowing for effective monitoring in various biological assays. Additionally, Phenol Red sodium salt acts as an antagonist of rat P2X1R and enhances the halogenating activity of myeloperoxidase, making it valuable for studies involving cellular mechanisms and enzyme activities. Its applications extend to cell culture and biochemical research where precise pH measurement is essential.

Cat. No.

A44624

CAS No.

569-64-2

Basic green 4

Synonyms: Malachite green

Basic Green 4, also known as Malachite Green, is a cationic dye primarily utilized for its bactericidal properties in aquaculture and for the determination of phosphates in laboratory settings. It is characterized by significant cytotoxicity and potential carcinogenic effects on mammalian cells, evidenced by IC50 values of 2.03 µM for HEp-2 human laryngeal cells and 13.8 µM for Caco-2 human colorectal adenocarcinoma cells. Additionally, Basic Green 4 has been associated with the promotion of liver tumor development, with a maximum absorbance wavelength of 621 nm.

Cat. No.

A44625

CAS No.

878019-47-7

Coumberone

Coumberone is a selective substrate for all AKR1C isoforms, functioning as a metabolic fluorogenic probe. It can be enzymatically reduced by the four members of the AKR1C family into the fluorescent product coumberol. This compound is useful in studying the catalytic activities and pharmacological roles of AKR1C enzymes in various biological contexts. Its fluorescent properties enable sensitive detection and quantitative analysis in research applications related to enzyme kinetics and metabolic profiling.

Cat. No.

A44626

CAS No.

2783-94-0

Sunset Yellow FCF

Synonyms: Orange Yellow S; Food Yellow 3; CI 15985

Sunset Yellow FCF is an orange azo dye that exhibits maximal absorption at a wavelength of 480 nm. This compound serves as a coloring agent in various applications, including food, cosmetics, and pharmaceuticals, and is utilized for its stability and vibrant hue. Its use in research allows for the study of dye behavior and interactions in biological systems.

Cat. No.

A44627

CAS No.

477-73-6

Safranin

Synonyms: Safranine T

Safranin, a phenazinium dye, serves as a spectroscopic probe and indicator due to its planar structure and cationic nature. It readily intercalates with biological macromolecules, including DNA and proteins, facilitating various imaging and labeling applications. Additionally, Safranin exhibits antibacterial activity against gram-positive bacteria such as Staphylococcus aureus and functions as a redox indicator for metal ion concentration assessments. This versatility makes it a valuable reagent in microbiological, biochemical, and analytical research.

Cat. No.

A44628

CAS No.

2280796-94-1

RT-AM

RT-AM is a glutathione fluorescent probe designed to monitor real-time glutathione dynamics in living cells through a reversible reaction mechanism. This pro-agent transforms into a highly sensitive fluorescent reporter upon interaction with thiols, enabling quantitative assessments of glutathione levels. RT-AM is essential for studying oxidative stress, cellular redox states, and related biochemical pathways in cellular and molecular research applications.

Cat. No.

A44629

CAS No.

531-53-3

Azure A chloride

Azure A chloride is a phenothiazine dye that primarily targets DNA for binding. This reagent is commonly utilized in agarose gel electrophoresis and polyacrylamide gel electrophoresis (PAGE) for the effective separation of DNA and protein fragments. Azure A chloride exhibits non-cooperative binding to double-stranded DNA through weak intercalation, inducing molecular conformational changes that affect rotational motion and optical characteristics. Its unique properties also allow for chemisorption on mild steel surfaces to form a protective film, as described by the Langmuir adsorption isotherm.

Cat. No.

A44630

CAS No.

2381-85-3

Nile blue chloride

Nile blue chloride is a photostable organic dye with strong fluorescent properties. It can be utilized in the development of ratiometric pH-sensitive probes for real-time monitoring of extracellular fluid pH in cancer research. Additionally, Nile blue chloride shows promise for investigation in the field of nonlinear optics.

Cat. No.

A44631

CAS No.

1416872-50-8

Sulfidefluor 7-AM

Synonyms: SF7-AM

Sulfidefluor 7-AM is a stable fluorescent probe specifically designed for the detection of hydrogen sulfide (H2S). This compound features an azide group and participates in click chemistry techniques, including copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules, as well as strain-promoted azide-alkyne cycloaddition (SPAAC) with DBCO or BCN substrates. It serves as a valuable tool for studying H2S dynamics in biological systems and facilitates the development of H2S-related research applications.

Cat. No.

A44632

CAS No.

78338-22-4

Thionin acetate

Synonyms: Thionine acetate

Thionin acetate is a cationic histological dye known for its metachromatic properties. It exhibits antibacterial activity and is commonly used in biological staining applications. This compound is effective in visualizing cell structures and can be applied in various histological and cytological studies.

Cat. No.

A44634

CAS No.

3567-69-9

Carmoisine

Synonyms: Azorubine; Acid Red 14; E122

Carmoisine, an azo dye, is primarily utilized as a colorant in various food applications. This compound exhibits strong coloring properties, making it ideal for use in the food and beverage industry. Research on Carmoisine may also extend to studies investigating its safety and regulatory aspects as a food additive.

Cat. No.

A44635

CAS No.

196504-57-1

8-Aminopyrene-1,3,6-trisulfonic acid trisodium

Synonyms: APTS

8-Aminopyrene-1,3,6-trisulfonic acid trisodium acts as an anionic fluorescent dye, exhibiting strong fluorescence with excitation at 425 nm and emission at 503 nm in pH 7.4 phosphate-buffered saline. Its fluorescence intensity remains stable across a pH range of 4 to 10 and is preserved when immobilized in hydrogel matrices through copolymerization. This compound is particularly useful in biochemistry for applications such as glucose sensing, contributing to various sensor technologies.

Cat. No.

A44636

CAS No.

569-61-9

Pararosaniline hydrochloride

Synonyms: Basic red 9

Pararosaniline hydrochloride is a basic dye that functions as a biological stain to visualize and track specific proteins. This compound exhibits pH sensitivity, with optimal staining occurring at a pH of 0.48 and a maximum absorption wavelength (λmax) of 549 nm. Additionally, Pararosaniline hydrochloride acts as a potent modifier of RNA splicing, making it useful in molecular biology research. It has applications in various analytical contexts, including the detection of sulfur dioxide and formaldehyde, as well as in the staining of bacteria and other microorganisms.

Cat. No.

A44637

CAS No.

17354-14-2

Solvent Blue 35

Synonyms: Sudan Blue II; Oil Blue 35

Solvent Blue 35, also known as Sudan Blue II, is a blue solvent dye primarily employed for coloring specific diesel fuels. This compound exhibits excellent solubility in organic solvents, making it useful in various industrial applications, including dyeing processes and as a tracer in fuel analysis. Its distinctive color properties allow for effective monitoring and identification in fuel-related research.

Cat. No.

A44638

CAS No.

85-86-9

Sudan III

Synonyms: Sudan Red III; Tetrazobenzene-β-naphthol; 111440 Red

Sudan III is a disazo dye that exhibits hydrophobic characteristics. It is primarily utilized in the staining of lipids in biological samples, facilitating the visualization of fat-containing tissues under a microscope. This compound is widely applied in histological studies and various biochemical assays to analyze lipid distribution and metabolism in research settings.

Cat. No.

A44640

CAS No.

6409-77-4

Nuclear Fast Red

Synonyms: Kernechtrot

Nuclear Fast Red is an anthraquinone dye that serves as a fluorescent probe targeting guanine. As a highly sensitive "off/on" probe, it is capable of detecting guanine with increased specificity. Additionally, Nuclear Fast Red is utilized as a histochemical and colorimetric reagent for calcium staining, often in combination with aluminum ions as a red nuclear counterstain. Its applications span various fields of biological research, including histology and nucleic acid detection.

Cat. No.

A44642

CAS No.

35661-51-9

9-Fluorenylmethyl carbazate

9-Fluorenylmethyl carbazate serves as a fluorescent labeling agent primarily used for the fluorimetric detection of glycans. Its ability to form stable fluorescent derivatives allows for sensitive and specific analysis in glycan profiling. This reagent is essential in various applications including carbohydrate biochemistry and glycomics research.