All Dyes

Cat. No.

B11051

CAS No.

3051946-11-0

APO-15

APO-15 is a phosphatidylserine-binding fluorescent probe designed for apoptosis imaging. This reagent demonstrates exceptional chemical stability in both proteolytic and oxidative environments, facilitating the quantification and visualization of drug-induced apoptosis in preclinical mouse models, as well as fixed tissue samples. With an excitation wavelength of 488 nm and emission at 525 nm, APO-15 is particularly valuable in research focusing on acute lung injury and breast cancer.

Cat. No.

B11052

CAS No.

216757-33-4

Ac-IEPD-AMC

Ac-IEPD-AMC is a fluorogenic substrate designed for the quantification of protease activity. Upon hydrolysis, Ac-IEPD-AMC releases the fluorescent molecule 7-amino-4-methylcoumarin (AMC), which exhibits strong fluorescence under UV illumination. This compound is valuable for investigating proteolytic enzyme functions and can be utilized in various assays to measure protease activities in biological samples.

Cat. No.

B11053

CAS No.

2260795-64-8

C11 BODIPY 505/515 MG

C11 BODIPY 505/515 MG is a fluorescently labeled glycerolipid with an excitation/emission wavelength of 495/503 nm. This compound enables the visualization and tracking of lipid dynamics in biological systems. It is widely utilized in cell biology and biochemistry for studying membrane composition and lipid metabolism.

Cat. No.

B11054

CAS No.

728912-45-6

Pentafluorobenzenesulfonyl fluorescein

Pentafluorobenzenesulfonyl fluorescein is a selective fluorescent probe designed for the detection of hydrogen peroxide (H2O2) within cellular environments. This compound exhibits minimal fluorescence in its native state, becoming markedly fluorescent upon cleavage of the sulfonyl linkage by H2O2. Its specific reactivity allows for effective monitoring of oxidative stress and related biological processes, making it a valuable tool for research in cell biology and redox signaling pathways.

Cat. No.

B11056

CAS No.

1811539-43-1

PA-JF549-Halo ligand

PA-JF549-Halo ligand is a photoactivatable fluorescent probe designed for targeting the HaloTag protein. Featuring the bright and photostable JF549 dye, this conjugate has intrinsic properties that facilitate localization to mitochondria, enhancing imaging quality. PA-JF549-Halo ligand is ideal for high-resolution single-molecule and super-resolution imaging of specific proteins in live cells, supporting applications in cellular and molecular biology research.

Cat. No.

B11058

CAS No.

5662-03-3

Quinophthalone

Quinophthalone is a synthetic dye known for its distinctive greenish-yellow coloration. It functions as a coloring agent for a variety of materials, emphasizing its versatility in applications such as textiles and plastics. Additionally, Quinophthalone demonstrates strong sensitizing properties in guinea pigs, with a threshold concentration for induction and challenge established at 10 ppm, highlighting its potential implications in toxicological studies and safety assessments.

Cat. No.

B11060

CAS No.

1266615-85-3

Ferrozine sodium hydrate

Ferrozine sodium hydrate is an iron dye reagent that selectively binds to divalent iron ions (Fe²⁺), forming a stable magenta complex. This complex exhibits a strong absorption peak at 562 nm, making it suitable for spectrophotometric analysis. Ferrozine sodium hydrate is widely employed in colorimetric assays to quantify iron levels in biological samples, providing essential data for studies on iron metabolism and related disorders.

Cat. No.

B11061

CAS No.

83-61-4

Alizarin Red S

Synonyms: ARS

Alizarin Red S is an anthraquinone derivative dye primarily utilized for visualizing calcium deposits. It forms a coordination bond with calcium ions, resulting in an orange-red fluorescence, making it useful for detecting osteoblast differentiation and screening calcium compounds in synovial fluid. This reagent is also commonly employed for bone staining in murine models. The excitation and emission wavelengths are 500 nm and 570 nm, respectively.

Cat. No.

B11062

CAS No.

635-90-5

1-Phenylpyrrole

Synonyms: N-Phenylpyrrole

1-Phenylpyrrole is a compound exhibiting dual fluorescence, characterized by distinct emission profiles based on solvent polarity. In nonpolar solvents, it displays a single fluorescent band, while in polar solvents, a second red-shifted emission band is observed. This unique behavior makes 1-Phenylpyrrole valuable for studies involving solvent effects on fluorescence, as well as applications in photonic devices and fluorescence-based assays.

Cat. No.

B11065

CAS No.

177332-37-5

Acridinium C2 NHS ester

Acridinium C2 NHS ester is a fluorescent dye that functions as a chemiluminescent label, specifically designed for the development of protein and nucleic acid probes. This reagent enables highly sensitive detection solutions, making it valuable in bioanalysis and diagnostics. Its broad applications in medical research, particularly in the monitoring and analysis of biomolecules, underscore its significance in advancing scientific studies.

Cat. No.

B11066

CAS No.

115-41-3

Catechol violet

Catechol violet is a complexometric indicator dye known for its versatility as a ligand in Cu(I)-catalyzed C-S coupling reactions. Its ability to form stable complexes makes it valuable in various analytical applications, allowing for the detection and quantification of metal ions in solution. This reagent is essential for researchers investigating metal-mediated reactions and complexation phenomena in chemical studies.

Cat. No.

B11068

CAS No.

94367-20-1

Suc-Leu-Tyr-AMC

Suc-Leu-Tyr-AMC is a fluorescent peptide substrate designed specifically for µ-calpain and m-calpain enzymes. It is characterized by an excitation wavelength of 360 nm and an emission wavelength of 460 nm, making it suitable for fluorescence-based assays. This reagent serves as a vital tool in studying calpain activity and related biological processes. Its application in research can aid in the understanding of proteolytic cleavage and its implications in various physiological and pathological conditions.

Cat. No.

B11069

CAS No.

133628-73-6

H-Asp(AMC)-OH

H-Asp(AMC)-OH is an amino acid derivative functioning as a fluorescent dye that is widely used in biochemical assays. This compound exhibits significant fluorescence properties, making it an excellent tool for studying protein interactions and enzyme activities. Importantly, H-Asp(AMC)-OH does not inhibit glycine transport at concentrations up to 0.25 mM, ensuring minimal interference in transport studies. Its applications include fluorescence microscopy and various biochemical assays that require sensitive detection of biomolecules.

Cat. No.

B11070

CAS No.

1631716-11-4

Ac-YEVD-AMC

Ac-YEVD-AMC is a fluorescent substrate specifically designed for the detection of caspase-1 and caspase-11 activity. Upon hydrolysis by these caspases, Ac-YEVD-AMC releases the fluorescent compound amino-4-methylcoumarin (AMC), enabling real-time monitoring of caspase activation in various biological assays. This reagent is suitable for research applications focused on inflammation, apoptosis, and other signaling pathways mediated by caspase activity.

Cat. No.

B11071

CAS No.

2148335-01-5

Bile acid probe 1

Bile Acid Probe 1 is a photoreactive chemical probe designed to selectively target bile acids through its clickable ester linkage. This reagent enables detailed studies of bile acid dynamics, transport mechanisms, and interactions within biological systems. It is an essential tool for researchers investigating bile acid metabolism, signaling pathways, and related diseases, providing insights into gastrointestinal functions and potential therapeutic interventions.

Cat. No.

B11072

CAS No.

128-80-3

Solvent Green 3

Solvent Green 3 is an anthraquinone-based fluorescent dye that targets biological samples for imaging applications. This dye exhibits strong fluorescence under UV light, making it suitable for the staining of cells, bacteria, and tissue samples in microscopy studies. Solvent Green 3 is particularly useful in biological research for visualizing cellular structures and processes, allowing for enhanced clarity in experimental analysis.

Cat. No.

B11075

CAS No.

98516-76-8

H-Glu-AMC-OH (H-Glu-AMC)

H-GLU-AMC-OH is a fluorescent peptide substrate specifically designed for the assessment of aminopeptidase A enzyme activity. This compound enables sensitive quantification and observation of enzyme kinetics in various biological samples. Its application is beneficial in studies involving peptide metabolism and enzyme regulation, providing valuable insights into aminotransferase functions.

Cat. No.

B11076

CAS No.

3027246-94-9

SPB-PEG4-AAD

SPB-PEG4-AAD is a BFPX probe that selectively crosslinks the Nkx2.5/DNA and p53/DNA complexes while exhibiting minimal interaction with DNA alone. This compound is valuable for studying protein-DNA interactions and investigating the role of transcription factors in gene regulation. Its unique properties make it a useful tool in molecular biology research.

Cat. No.

B11078

CAS No.

149695-85-2

(Z-Ala-Ala-Ala-Ala)2Rh110

Synonyms: (Z-Ala-Ala-Ala-Ala)2Rhodamine110; bis-CBZ-L-alanyl-L-arginine amide Rhodamine 110

(Z-Ala-Ala-Ala-Ala)2Rh110 is a fluorogenic elastase substrate that exhibits high sensitivity. Initially colorless and nonfluorescent, this compound is specifically cleaved by elastase, resulting in the production of the fluorescent rhodamine 110, which can be effectively measured at an excitation wavelength of 485 nm and an emission wavelength of 525 nm. This substrate is valuable for studying elastase activity and can be applied in various biochemical assays and research applications focused on protease activity.

Cat. No.

B11080

CAS No.

133233-38-2

Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2

Abz-Thr-Ile-Nle-p-nitro-Phe-Gln-Arg-NH2 is a fluorogenic substrate designed for use in fluorescence-based screening assays. This compound exhibits enhanced fluorescence upon enzymatic cleavage, making it suitable for the study of enzymatic activity and proteolytic processes. Its applications extend to substrate specificity assays and the characterization of proteases in various biological research contexts.

Cat. No.

B11081

CAS No.

3027246-93-8

SPB-AAD

SPB-AAD is a BFPX probe that facilitates covalent capture of in vitro assembled MEF2/DNA and NFAT1/DNA complexes. This reagent is valuable for studying gene regulation mechanisms involving these transcription factors, providing insights into cellular signaling pathways. Its applications extend to molecular biology research, particularly in investigating gene expression and transcriptional activity.

Cat. No.

B11083

CAS No.

1224691-12-6

Pantothenate-AMC

Pantothenate-AMC is a fluorogenic substrate specifically designed for the detection of vanin-1 enzymatic activity, which plays a crucial role in L-pantothenic acid recycling. Upon cleavage by vanin-1, the substrate releases 7-amino-7-methylcoumarin (AMC), resulting in fluorescence that can be quantitatively measured. With excitation and emission maxima at 340-360 nm and 440-460 nm, respectively, Pantothenate-AMC is a valuable tool for research applications focused on enzymatic assays and metabolic studies.

Cat. No.

B11084

CAS No.

926905-86-4

Cy3B maleimide

Cy3B maleimide is a mono-reactive fluorescent dye that targets thiol groups, enabling the selective conjugation of the Cyanine3B fluorophore to proteins and peptides with cysteine residues, as well as to other thiolated compounds, including thiol-containing oligonucleotides. This dye exhibits enhanced fluorescence quantum yield and superior photostability compared to traditional Cy3 dyes, making it an excellent choice for applications in fluorescence microscopy, flow cytometry, and various labeling studies in biochemical research. The versatility and efficiency of Cy3B maleimide offer valuable tools for studying protein interactions and intracellular processes.

Cat. No.

B11085

CAS No.

888327-74-0

2-Hydroxy nile red trifluoromethanesulfonate

2-Hydroxy nile red trifluoromethanesulfonate is a fluorescent probe that functions by integrating into oligodeoxyribonucleic acid as a nucleotide replacement. This compound exhibits significant utility in monitoring polar changes within tumor microenvironments, thereby aiding in cancer research. Its application as a DNA probe facilitates the study of nucleic acid dynamics and cellular responses, making it invaluable for researchers exploring tumor biology and related fields.

Cat. No.

B11086

CAS No.

761401-89-2

DANP

DANP is a bulge base recognition probe that specifically interacts with single cytosine and thymine bulges in duplex DNA. Its high affinity enables the stabilization of both cytosine and thymine bulges, making it a useful tool for studying DNA structures. This probe can be applied in research involving DNA repair mechanisms, gene regulation, and nucleic acid interactions.