All Dyes

Cat. No.

B11205

CAS No.

116763-35-0

5(6)-Carboxyrhodamine 110

5(6)-Carboxyrhodamine 110 is an amine-reactive fluorescent probe that targets nucleic acids, proteins, and cells, exhibiting excitation and emission maxima at 498 nm and 530 nm, respectively. This compound is widely utilized in various applications, including fluorescence microscopy, flow cytometry, and cellular imaging, facilitating studies of biomolecular interactions and cellular processes. The stability and brightness of 5(6)-Carboxyrhodamine 110 make it an invaluable tool in molecular biology and biochemistry research.

Cat. No.

B11207

CAS No.

223759-19-1

NPE-caged-HPTS sodium

NPE-caged-HPTS sodium is a caged fluorophore that becomes fluorescent upon the release of the free highly polar fluorophore HPTS. With excitation at 470 nm and emission at 525 nm, HPTS facilitates the rapid and uniform monitoring of diffusion processes within tissues. This characteristic makes it a valuable tool for studying diffusion coefficients comparable to that of synaptic L-glutamate, providing insights into cellular dynamics.

Cat. No.

B11208

CAS No.

689263-76-1

NBD dodecanoic acid N-succinimidyl ester

NBD dodecanoic acid N-succinimidyl ester is a fluorescent dye that incorporates a long-chain fatty acid moiety, enabling targeting of lipid-rich cellular environments. This compound can be utilized for labeling and tracking biological molecules, facilitating fluorescence microscopy and imaging studies. Its ability to stably conjugate to amine-containing biomolecules enhances its application in cellular and molecular biology research.

Cat. No.

B11209

CAS No.

1616957-48-2

Cbz-Lys-Lys-PABA-AMC diTFA

Cbz-Lys-Lys-PABA-AMC diTFA is a fluorogenic peptide designed to function as a substrate for proteases. It exhibits high specificity for certain enzymes, enabling the detection and quantification of proteolytic activity in biological samples. This compound is valuable in studies requiring the measurement of enzyme kinetics, protease activity, and related metabolic processes.

Cat. No.

B11210

CAS No.

2260669-68-7

Cy5-DSPE

Cy5-DSPE is a fluorescent phospholipid that serves as a vital tool for membrane labeling and imaging applications. Its unique fluorescent properties enable researchers to study cell membrane dynamics, lipid interactions, and membrane-associated processes in living cells. This compound is particularly useful for applications in fluorescence microscopy and various biophysical assays, contributing to advanced understanding in cellular research and diagnostics.

Cat. No.

B11211

CAS No.

885597-18-2

1,N6-Ethenoadenosine 5'-monophosphate sodium

Synonyms: 1,N6-Etheno-AMP sodium; 1,N6-ε-AMP sodium

1,N6-Ethenoadenosine 5'-monophosphate sodium is a highly fluorescent analog of adenosine 5'-monophosphate (AMP) designed for use as a fluorescent probe. This compound exhibits strong fluorescence properties, with excitation occurring in the range of 250-300 nm and emission at 415 nm, enabling sensitive detection at low concentrations. It serves as a valuable tool in research applications focused on adenosine signaling pathways, allowing for the investigation of cellular mechanisms involving AMP.

Cat. No.

B11212

CAS No.

949898-96-8

Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans

Dabsyl-Leu-Gly-Gly-Gly-Ala-Edans is a Dabsyl-labeled peptide designed as a fluorophore substrate for studying peptidase activity. It serves as a specific probe for evaluating the enzymatic activity of the LasA protease from Pseudomonas aeruginosa. This reagent is valuable in research focused on protease function and substrate specificity, facilitating insights into microbial proteolytic mechanisms.

Cat. No.

B11214

CAS No.

1392300-20-7

Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA

Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA is a fluorogenic substrate specifically designed for matrix metalloproteinases (MMPs). Upon cleavage by MMPs, 7-methoxycoumarin-4 acetyl (Mac) is released, exhibiting fluorescence that can be quantified to assess MMP activity. This substrate is particularly useful in studying the role of MMPs in various biological processes and diseases. Mac shows excitation and emission wavelengths at 328 nm and 420 nm, respectively, facilitating sensitive detection in biochemical assays.

Cat. No.

B11215

CAS No.

2260795-66-0

18:1-18:1-C11 BODIPY 505/515 TG

18:1-18:1-C11 BODIPY 505/515 TG is a fluorescently labeled triglyceride designed for the measurement of triacylglycerol hydrolases. With excitation and emission wavelengths of 495 nm and 503 nm, respectively, this reagent serves as a valuable tool for studying lipid metabolism and enzyme activity in various biological systems. It is particularly suitable for assays investigating triglyceride turnover and lipid homeostasis.

Cat. No.

B11216

CAS No.

263889-50-5

Di-sulfo squarefluor 640/660 free acid

Di-sulfo squarefluor 640/660 free acid is a fluorescent lipid designed for the visualization of cell membranes, with excitation and emission wavelengths of 640 nm and 660 nm, respectively. This reagent is suitable for applications in fluorescence microscopy and cellular imaging, facilitating studies of membrane dynamics and cellular architecture. Its distinct fluorescence properties enable enhanced contrast and clarity in biological assays.

Cat. No.

B11217

CAS No.

846022-21-7

AOI 987

AOI 987 is an oxazine dye that serves as a fluorescent molecule, enabling visual tracking of biological macromolecules. Its ability to bind effectively to various biomolecules facilitates its use in fluorescence microscopy and cellular imaging applications, making it a valuable tool for researchers investigating cellular processes and biomolecular interactions.

Cat. No.

B11219

CAS No.

2230217-17-9

Pegulicianine

Synonyms: LUM015 free base

Pegulicianine is an activatable fluorescent imaging agent primarily used in fluorescence-guided surgery. Its properties enable effective visualization of tumor margins during surgical procedures, particularly in breast cancer. This imaging agent enhances the accuracy of tumor resection, thereby improving patient outcomes in oncological surgeries.

Cat. No.

B11220

CAS No.

1621585-17-8

PF-06649283

PF-06649283 is a fluorescent dye that exhibits potential intracellular activity. Its effects may be influenced by cellular metabolism, protein-protein interactions, post-translational modifications, and asymmetric localization within cells. This compound demonstrates variable potency at the cellular level compared to recombinant enzymes, a distinction that is important for drug discovery applications. The enhanced intracellular potency of PF-06649283 is essential for its use as both a probe and a therapeutic agent in research settings.

Cat. No.

B11222

CAS No.

145613-12-3

D-Luciferin phosphate trisodium

D-Luciferin phosphate trisodium is a bioluminescent substrate specifically designed for firefly luciferase. Upon dephosphorylation by alkaline phosphatase, it releases the fluorescent compound D-fluorescein, enabling highly sensitive detection of phosphatase activity. This reagent is widely utilized in biochemical assays and molecular biology research to study enzyme kinetics and substrate interactions.

Cat. No.

B11223

CAS No.

73554-94-6

Boc-Glu(OBzl)-Gly-Arg-AMC

Boc-Glu(OBzl)-Gly-Arg-AMC is a fluorogenic substrate specifically designed for the detection of factors IXa and XIIa. Upon enzymatic cleavage of the amide bond between arginine and the methylcoumarin amide moiety, it releases the fluorescent compound 7-Amino-4-methylcoumarin. This substrate is valuable for biochemical assays focused on studying coagulation pathways and enzyme activity.

Cat. No.

B11226

CAS No.

50663-82-6

2-Aza-ε-adenosine

Synonyms: 2-Aza-1,N6-ethenoadenosine

2-Aza-ε-adenosine is a multifunctional dye recognized for its utility in biological research. This compound facilitates the observation and analysis of cellular structures, tracking of biomolecules, and evaluation of cell functions, making it an invaluable tool in various research applications, including tissue pathology and microbiological monitoring. Additionally, 2-Aza-ε-adenosine finds diverse uses beyond biological studies, such as in textile dyeing and emerging technologies like dye-sensitized solar cells.

Cat. No.

B11227

CAS No.

190836-86-3

TRH-AMC

TRH-AMC serves as a fluorogenic substrate specifically for the enzyme that degrades thyrotropin-releasing hormone (TRH). By utilizing this substrate in coupled assays, researchers can effectively study the biochemical activity of TRH-degrading ectoenzymes. This compound is valuable for investigating the enzymatic processes involved in hormonal regulation and related physiological pathways.

Cat. No.

B11231

CAS No.

310427-95-3

M-2420

M-2420 is a fluorogenic substrate designed to target the β-secretase site of the Swedish mutation of amyloid precursor protein (APP). This compound exhibits key biological activity by facilitating the detection and quantification of β-secretase activity, which is crucial for understanding amyloidogenic processes in Alzheimer’s disease. M-2420 is suitable for research applications focused on neurodegenerative diseases and protein cleavage mechanisms.

Cat. No.

B11233

CAS No.

1888323-45-2

GSH Tracker Probe

GSH Tracker Probe (CPDSA) is a cyanine-based fluorescent probe designed for the selective detection of glutathione (GSH) with near-infrared (NIR) emission characteristics. Excited at 635 nm and emitting between 655-755 nm, this probe enables real-time monitoring and imaging of GSH levels in live cells and in vivo models. It serves as a valuable tool for studies related to oxidative stress, cellular redox states, and various pathological conditions linked to glutathione alterations.

Cat. No.

B11234

CAS No.

219138-08-6

Z-VDVAD-AFC

Z-VDVAD-AFC is a fluorogenic substrate designed to measure the activity of cysteine protease 3 (Caspase-3). Upon hydrolysis, Z-VDVAD-AFC releases 7-amino-4-trifluoromethylcoumarin (AFC), which exhibits strong fluorescence under ultraviolet light. This property enables researchers to monitor proteolytic activity in various biological assays, facilitating studies in apoptosis, cell signaling, and disease mechanisms.

Cat. No.

B11235

CAS No.

8064-60-6

Primulin

Synonyms: Primuline

Primulin is a fluorescent dye that exhibits strong binding affinity for albumin, making it a valuable tool in various analytical and biological studies. This compound effectively labels plant cell walls and distinguishes between live and dead spermatozoa through distinct fluorescence patterns. In neurobiology, Primulin serves as a retrograde axonal tracer, while its derivatives demonstrate inhibitory activity against HCV NS3 and interference with dengue virus NS3-mediated ATP hydrolysis. Additionally, Primulin disrupts HCV replicase assembly, highlighting its potential in virology research applications.

Cat. No.

B11236

CAS No.

3077081-53-6

Cyanine 3.5 azide

Cyanine 3.5 azide is a fluorescent dye featuring an azide functional group, making it suitable for click chemistry applications. It effectively participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing compounds, as well as in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups. This versatile reagent exhibits excitation and emission maxima at 591 nm and 604 nm, respectively, and is ideal for labeling and imaging studies in chemical biology and biomolecular research.

Cat. No.

B11237

CAS No.

1286479-53-5

4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one

4-Methyl-7-(2-nitrophenoxy)-2H-chromen-2-one functions as a selective fluorescent probe for selenols, utilizing a nucleophilic aromatic substitution mechanism. This compound demonstrates the ability to accurately detect selenols in neutral aqueous environments while minimizing interference from thiols, amines, and alcohols commonly found in biological systems. Its applications include quantifying selenium levels in selenoenzymes and visualizing endogenous selenol activity in live cells.

Cat. No.

B11239

CAS No.

3091879-84-1

Meso-Cl cyanine 7 free acid chloride

Meso-Cl cyanine 7 free acid chloride is a fluorescent dye targeting amine groups on biomolecules. It is particularly useful for labeling antibodies, nucleic acids, and proteins, enabling enhanced visualization in various fluorescence detection techniques including microscopy and flow cytometry. The dye exhibits excitation and emission wavelengths of 778 nm and 805 nm, respectively, making it suitable for multiplex applications in biological research.

Cat. No.

B11242

CAS No.

1926163-46-3

Ac-GAK-AMC

Ac-GAK-AMC is a fluorescent substrate designed to measure protease activity through the hydrolysis of the compound. Upon enzymatic cleavage by proteases, Ac-GAK-AMC releases 7-amino-4-methylcoumarin (AMC), resulting in a detectable fluorescent signal. This reagent is suitable for various research applications, including enzyme assays and studying proteolytic pathways.