All Dyes

Cat. No.

A25017

CAS No.

168482-84-6

Calcein Blue AM

Calcein Blue AM is a fluorescent cellular dye that targets and labels live cells, providing valuable insights into cell viability and health. It exhibits anti-inflammatory properties, making it a useful reagent for research applications involving inflammatory processes. This compound is commonly employed in studies related to cell proliferation, apoptosis, and cellular responses to therapeutic agents in various disease models.

Cat. No.

A25028

CAS No.

2240163-05-5

HKPerox-1

HKPerox-1 is a highly sensitive green fluorescent probe designed for the specific detection of hydrogen peroxide (H2O2) in living cells. It exhibits a maximum excitation wavelength of 520 nm and an emission wavelength of 543 nm, enabling effective visualization of oxidative stress and reactive oxygen species. This probe is ideal for research applications involving cellular metabolism, oxidative stress studies, and the assessment of redox biology in various experimental contexts.

Cat. No.

A25029

CAS No.

1574299-37-8

Sel-green

Sel-green is a selective selenol fluorescent probe designed to quantify selenium (Sec) content in selenoenzymes such as thioredoxin reductase. This reagent enables the imaging of endogenous Sec in live HepG2 cells, making it invaluable for studies focusing on selenium metabolism and its implications in cellular physiology. Researchers can utilize Sel-green to gain insights into the role of selenoenzymes in various biological processes and disease states.

Cat. No.

A25030

CAS No.

852057-94-4

KMG-104

KMG-104 is a cell-impermeant fluorescent probe specifically designed for the selective detection of Mg2+ ions. This reagent enables real-time imaging of Mg2+ mobilization in the cytoplasm across various cell types, making it a valuable tool for studies involving cellular signaling and ion homeostasis. Its high specificity and sensitivity facilitate the exploration of magnesium's role in physiological and pathological processes.

Cat. No.

A25031

CAS No.

114301-97-2

C6-NBD Sphinganine

Synonyms: dhCerC6NBD

C6-NBD Sphinganine is a fluorescent analog of sphinganine that serves as a potent fatty acid fluorescent marker. This compound enables the visualization and tracking of fatty acids in cellular and tissue studies, facilitating research in lipid metabolism and cellular signaling pathways. Its applications extend to studying lipid-related diseases and understanding the dynamics of sphingolipid metabolism.

Cat. No.

A25032

CAS No.

886212-87-9

10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505/515

10-(4-(Bis(2-acetoxyethyl)amino)phenyl)-BODIPY 505/515 is a highly sensitive fluorescent dye specifically designed for the detection of Cu2+ ions. This compound exhibits enhanced fluorescence properties upon binding to copper ions, making it a valuable tool for studying metal ion distribution and dynamics in biological systems. Its application extends to fluorescence imaging and sensing in various research contexts, including environmental monitoring and biological assays.

Cat. No.

A25034

CAS No.

2322286-81-5

DMHBO+

DMHBO+ is a cationic chromophore known for its high-affinity binding to the Chili aptamer, exhibiting a dissociation constant (Kd) of 12 nM. The Chili-DMHBO+ complex serves as an effective fluorescence donor for FRET applications with the rhodamine dye Atto 590, facilitating RNA imaging within cellular environments. With excitation and emission wavelengths of 456 nm and 592 nm respectively, DMHBO+ is a valuable tool for researchers studying RNA dynamics and interactions.

Cat. No.

A25035

CAS No.

1825332-75-9

Alexa fluor 647 maleimide

Alexa Fluor 647 maleimide is a far-red-emitting fluorescent dye designed for the selective labeling of protein thiol groups, particularly cysteine residues (Ex/Em = 656/670 nm). This reagent facilitates the attachment of the AF 647 fluorophore to various biomolecules, including proteins, peptides, and thiol-containing oligonucleotides. Its exceptional brightness makes it valuable for applications in cell biology, neuroscience, and disease diagnostics, enabling advanced fluorescence imaging and analysis.

Cat. No.

A25036

CAS No.

1372642-78-8

KMG-301AM TFA

KMG-301AM TFA is an acetoxymethyl ester derivative of KMG-301, designed as a fluorescent probe targeting Mg2+ within mitochondria. Once inside the mitochondria, it is hydrolyzed to KMG-301, which selectively measures Mg2+ concentrations in live cells, as it remains confined within the mitochondria due to the impermeability of the mitochondrial membrane. This probe is suitable for assessing Mg2+ transport and monitoring changes in mitochondrial Mg2+ levels, providing valuable insights in cellular models of mitochondrial function and dysfunction.

Cat. No.

A25037

CAS No.

916753-61-2

BHQ-1 NHS

BHQ-1 NHS is a fluorescent dye designed for efficient labeling of nucleotide sequences. This compound serves as a quencher, offering enhanced fluorescence signaling for applications in nucleic acid research and diagnostics. BHQ-1 NHS is particularly valuable in the development of real-time PCR assays and other molecular biology techniques requiring precise fluorescence modulation.

Cat. No.

A25038

CAS No.

2897614-59-2

H-FluNox

H-FluNox is a selective fluorescent probe designed to detect labile heme through biomimetic N-oxide deoxygenation, which activates its fluorescence. This compound demonstrates over 100-fold selectivity for labile heme compared to Fe(II), facilitating the differentiation of labile heme from intracellular Fe(II) pools. H-FluNox's high sensitivity enables the detection of labile heme at the subcellular level, making it an invaluable tool for studies of heme dynamics and related biological processes.

Cat. No.

A25040

CAS No.

167095-09-2

MitoMark Red I

MitoMark Red I is a fluorescent dye specifically designed to target mitochondria in viable cells. This red fluorescent marker exhibits a peak excitation wavelength of 578 nm and an emission at 599 nm, enabling precise visualization of mitochondrial activity and dynamics. It is widely utilized in cellular and molecular biology research to study mitochondrial function, cell viability, and related physiological processes.

Cat. No.

A25041

CAS No.

2929446-76-2

EtS-DMAB

Synonyms: HClO-green

EtS-DMAB is a fluorescent probe designed for the selective detection of hypochlorous acid (HOCl). Exhibiting fluorescence with excitation at 440 nm and emission at 610 nm, it is used to visualize both exogenous and endogenous levels of HOCl in live cells. This compound is valuable for studies involving oxidative stress and inflammation, providing insights into cellular responses under specific pathological conditions.

Cat. No.

A25042

CAS No.

61255-63-8

DHPDS disodium salt

DHPDS disodium salt is a pH-sensitive fluorescent dye that enables the measurement of intracellular pH (pHi). This compound is particularly useful in experimental setups involving isolated perfused rat liver, where it facilitates the assessment of pH variations through surface fluorescence. Its application extends to various biological studies requiring precise pH measurements in living cells.

Cat. No.

A25173

CAS No.

189275-74-9

Ac-Trp-Glu-His-Asp-AMC

Synonyms: AC-WEHD-AMC

Ac-Trp-Glu-His-Asp-AMC is a specific fluorogenic substrate designed for caspase-1 detection and activity measurement. This compound exhibits high sensitivity and selectivity for caspase-1, enabling the quantitative assessment of apoptotic processes and inflammatory pathways. Its application in fluorescence assays facilitates the study of caspase-1's role in various biological contexts, including immune responses and cell death mechanisms.

Cat. No.

A25206

CAS No.

189696-20-6

Mca-DEVDAP-K(Dnp)-OH

Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate specifically designed for the quantification of caspase-3 activity. Utilizing the caspase-3 recognition sequence DEVD, this substrate facilitates the detection of caspase-3-mediated apoptosis in various biological samples. It is widely applied in research focused on programmed cell death and can be utilized in high-throughput screening assays to evaluate the efficacy of anti-apoptotic and pro-apoptotic compounds.

Cat. No.

A25212

CAS No.

210344-99-3

Ac-WEHD-AFC

Ac-WEHD-AFC is a fluorogenic substrate specifically designed for the detection of caspase-1 activity. This compound enables the quantitative measurement of caspase-1 enzymatic function, making it a valuable tool in studies related to tumorigenesis and inflammatory processes. Its sensitive fluorescence readout facilitates the assessment of caspase-1 involvement in various biological systems.

Cat. No.

A25322

CAS No.

1926163-65-6

Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone

Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone is a potent and cell-permeable inhibitor of caspase-3, acting through irreversible binding to the activated form in apoptotic cells. This reagent exhibits significant fluorescence, allowing for quantitative analysis via flow cytometry, microwell plate readers, or fluorescence microscopy. Its application is crucial for studying apoptosis and characterizing caspase-3 activity in various biological systems.

Cat. No.

A25324

CAS No.

223538-61-2

Z-DEVD-R110

Synonyms: (Z-Asp-Glu-Val-Asp)₂-Rhodamine 110

Z-DEVD-R110 is a fluorogenic substrate specifically designed for the detection of caspase-3 and caspase-7 activity. Composed of two DEVD peptide sequences linked to the rhodamine 110 fluorophore, this reagent is valuable for studying apoptotic processes in various biological systems. Its ability to provide quantitative measurements of caspase activity makes it an essential tool in apoptosis research and related studies.

Cat. No.

A25326

CAS No.

189696-01-3

Mca-YVADAP-Lys(Dnp)-OH

Mca-YVADAP-Lys(Dnp)-OH is a fluorogenic substrate designed for the characterization of caspase-1 and angiotensin-converting enzyme 2 (ACE2) activity. This compound enables the detection of enzymatic activity through fluorescence, making it valuable for studies focused on apoptosis and cardiovascular signaling pathways. It is suitable for use in various assays aimed at exploring the roles of these enzymes in cellular processes and disease states.

Cat. No.

A25327

CAS No.

219138-06-4

Z-VEID-AFC

Z-VEID-AFC is a fluorescent substrate specifically designed for the detection of caspase-6 activity. Upon cleavage by active caspase-6, it releases a fluorescent signal, making it useful for monitoring apoptotic processes in various biological systems. This reagent serves as a valuable tool in studies related to cell death, neurodegeneration, and tumor biology, facilitating the investigation of caspase-related pathways in research applications.

Cat. No.

A25446

CAS No.

210345-01-0

Ac-VEID-AFC

Ac-VEID-AFC is a fluorogenic substrate specifically designed for the detection of caspase-6 activity. Its cleavage by caspase-6 produces a fluorescent signal, making it a valuable tool for assessing apoptotic processes and related signaling pathways in various biological systems. This substrate is widely utilized in research applications focused on cell death, inflammation, and neurodegenerative diseases.

Cat. No.

A25451

CAS No.

919515-51-8

Ac-VRPR-AMC

Ac-VRPR-AMC is a fluorogenic substrate specifically designed for the detection of metacaspase activity. This compound is utilized in biochemical assays to measure metacaspase activity, making it a valuable tool for research in apoptosis and programmed cell death. Its fluorescence properties enable sensitive detection, facilitating studies on metacaspase function in various biological systems.

Cat. No.

A25459

CAS No.

1135416-11-3

Z-DEVD-AFC

Z-DEVD-AFC is a fluorogenic substrate specifically designed for the detection of caspase-3 activity. Upon cleavage by caspase-3, the AFC fluorophore undergoes a significant shift in fluorescence, enabling precise measurement of enzyme activity. This reagent is highly useful in research applications focused on apoptosis and caspase-related pathways, providing a reliable tool for studying cell death mechanisms.

Cat. No.

A25486

CAS No.

292633-16-0

Ac-LEHD-AMC

Ac-LEHD-AMC is a fluorogenic substrate specifically designed for the detection of caspase-9 activity. Upon hydrolysis by caspase-9, Ac-LEHD-AMC releases the AMC fluorophore, which emits fluorescence detectable at an excitation wavelength of 341 nm and an emission wavelength of 441 nm. This substrate is ideal for quantifying caspase-9 activity in various biological samples, facilitating research in apoptosis and related signaling pathways.