All Dyes

Cat. No.

A43670

CAS No.

61926-22-5

Ethidium homodimer

Synonyms: EthD-1

Ethidium homodimer is a high-affinity fluorescent nucleic acid dye targeting DNA and RNA. It exhibits enhanced fluorescence upon binding, with an increase of over 30 times, making it an effective tool for detecting nucleic acids in various biological samples, including mammalian cells, bacteria, yeast, and fungi. Due to its positive charge, Ethidium homodimer is unable to penetrate live cell membranes; however, it can access the nuclei of dead cells, resulting in the emission of red fluorescence. This characteristic makes it suitable for applications involving cell viability and nucleic acid detection, with an excitation/emission wavelength of 528/617 nm.

Cat. No.

A43671

CAS No.

1253643-88-7

DiAzKs

Synonyms: H-L-Photo-lysine

DiAzKs (H-L-Photo-lysine) is a diazirine-containing amino acid that functions as a photo-crosslinker. This compound enables site-selective incorporation into proteins, facilitating the study of protein-protein interactions both in vitro and in living cells. Activated by UV light, DiAzKs serves as an effective probe for photo-crosslinking applications in chemical biology and biophysical research.

Cat. No.

A43673

CAS No.

1170856-93-5

Calcein (tetraethyl ester)

Synonyms: Fluorexon tetraethyl ester

Calcein (tetraethyl ester) is a fluorescent dye that permeates cellular membranes, enabling its use in live cell imaging. This compound is widely utilized for assessing cell viability and for short-term labeling applications in biological research. Its strong fluorescence allows for effective visualization of cellular processes in various experimental contexts.

Cat. No.

A43674

CAS No.

91416-20-5

Propidium monoazide

Propidium monoazide (PMA) is a cell-impermeant photoreactive DNA-binding dye that selectively targets double-stranded DNA (dsDNA). It effectively prevents the amplification of DNA derived from dead bacteria during polymerase chain reaction (PCR), enhancing both the specificity and sensitivity of PCR assays. Additionally, PMA serves as a click chemistry reagent, containing an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, DBCO, or BCN groups, facilitating advanced chemical labeling and analysis in research applications.

Cat. No.

A43677

CAS No.

1522117-83-4

FBBBE

FBBBE is a selective fluorescent dye for the detection of hydrogen peroxide (H2O2) within cells. Upon exposure to intracellular H2O2, FBBBE undergoes a chemical transformation to fluorescein, leading to enhanced intracellular fluorescence (Ex=480 nm, Em=512 nm). This compound is valuable in studies examining oxidative stress and cellular responses to reactive oxygen species.

Cat. No.

A43678

CAS No.

128724-35-6

5(6)-Carboxynaphthofluorescein

5(6)-Carboxynaphthofluorescein is a pH-sensitive fluorophore known for its ability to fluoresce within an alkaline pH range. This compound serves as an effective fluorescent pH indicator, with excitation and emission wavelengths of 593 nm and 668 nm, respectively. It is particularly useful in the development of fiber-optic pH sensors and various biological and chemical research applications that require real-time pH monitoring.

Cat. No.

A43679

CAS No.

254117-01-6

C12 NBD Sphingomyelin

C12 NBD Sphingomyelin serves as a substrate for sphingomyelinase, incorporating a fluorescent C12 nitrobenzoxadiazole tag. This reagent enables the study of sphingomyelin metabolism and transport under fluorescence microscopy or spectroscopy, with an excitation wavelength of 470 nm and emission at 525 nm. Its application is critical for researchers investigating sphingolipid dynamics and related cellular processes.

Cat. No.

A43680

CAS No.

113694-64-7

Fura-2 pentapotassium

Fura-2 pentapotassium is a cell-impermeable fluorescent dye designed for intracellular calcium imaging, targeting Ca2+ ions. It exhibits an emission wavelength of 510 nm, with excitation wavelengths at 340 nm and 380 nm. The fluorescence intensity ratio of 340 nm to 380 nm is directly proportional to intracellular Ca2+ levels, making it a valuable tool for studies related to calcium signaling and cellular physiology.

Cat. No.

A43681

CAS No.

7057-57-0

Meldola blue

Meldola blue is a fluorescent dye primarily used as a biosensor for measuring lactate levels in serum. This reagent is designed for application on screen-printed carbon electrodes modified with Meldola's Blue-Reinecke salt (MBRS-SPCE) and incorporates the lactate dehydrogenase NAD+-dependent enzyme derived from pig heart, in conjunction with NAD+. It facilitates sensitive detection of lactate, making it valuable for research in metabolic studies and clinical diagnostics.

Cat. No.

A43682

CAS No.

2308035-47-2

(±)-ANAP hydrochloride

(±)-ANAP hydrochloride is an unnatural amino acid analog of prodan that functions as a fluorescent probe, enhancing the sensitivity to environmental changes. Its unique fluorescent properties make it valuable for studying protein conformational dynamics and interactions in various biological systems. This reagent is commonly utilized in fluorescence spectroscopy and microscopy applications to monitor changes in cellular environments.

Cat. No.

A43684

CAS No.

2653341-17-2

AIE-ER

AIE-ER is an advanced fluorescent probe designed for targeting the endoplasmic reticulum (ER), functioning through the aggregation-induced emission (AIE) mechanism. This probe displays exceptional photostability and high brightness, making it suitable for sensitive imaging applications. AIE-ER enables researchers to investigate ER-related pathologies, providing insights into cellular processes and disease mechanisms associated with ER dysfunction.

Cat. No.

A43685

CAS No.

1246303-05-8

3-C12-NBD-cholesterol

Synonyms: 3-Dodecanoyl-NBD-cholesterol

3-C12-NBD-cholesterol is a fluorescent cholesterol analog that targets cellular membranes to facilitate the study of cholesterol trafficking dynamics. This compound allows for real-time visualization and quantification of membrane and intracellular cholesterol distribution in various biological systems. It is an essential tool for investigating membrane biology, lipid metabolism, and the role of cholesterol in cellular processes.

Cat. No.

A43686

CAS No.

1152-14-3

Resorufin acetate

Resorufin acetate is a fluorescent dye that selectively targets hydrazine, enabling sensitive detection in various biological samples. This compound exhibits strong fluorescence upon reduction, making it a valuable tool in research applications focused on environmental monitoring, biochemical assays, and the study of oxidative stress. Its utility in detecting hydrazine enhances analytical capabilities in both research and laboratory settings.

Cat. No.

A43688

CAS No.

124549-11-7

PBFI

PBFI is a cell-impermeant fluorescent indicator primarily targeting potassium ions (K+). It is utilized for quantitative determination of K+ concentrations, exhibiting excitation and emission maxima at 340/500 nm and 380/500 nm, respectively. This reagent is essential for research applications involving ion channel studies and cellular signaling mechanisms related to potassium homeostasis.

Cat. No.

A43689

CAS No.

10401-59-9

9-Anthryldiazomethane

9-Anthryldiazomethane is a fluorescent labeling reagent that selectively targets fatty acids and their derivatives for detection. This compound enables sensitive fluorescence-based assays, facilitating the study of lipid metabolism and related biological processes. Its application in fluorescent labeling makes it a valuable tool in biochemical research.

Cat. No.

A43691

CAS No.

155815-98-8

Hoechst 33342 analog 2 trihydrochloride

Hoechst 33342 analog 2 trihydrochloride is a DNA intercalating agent primarily targeting A/T-rich regions within the double-stranded DNA. This live-cell nuclear marker exhibits enhanced fluorescence upon binding, making it an effective tool for cell labeling in various biological studies. Its fluorescence intensity is also influenced by the pH of the solution, which can be advantageous for certain imaging applications. This reagent is widely used in research involving cell cycle analysis, apoptosis detection, and chromatin studies.

Cat. No.

A43692

CAS No.

195136-58-4

2',7'-Difluorofluorescein

Synonyms: Oregon green 488

2',7'-Difluorofluorescein is a pH-sensitive fluorescent probe with a pKa of approximately 4.7. It provides ratiometric pH analysis through altered fluorescence intensity upon excitation at 488 nm, facilitating quantitative pH measurements between 2 and 7, particularly in submicron aerosol particles. This compound is notable for its ability to undergo buffer-mediated excited-state proton transfer and maintain stable fluorescence characteristics in physiological pH ranges, making it suitable for applications in fluorescent imaging, calcium indicator systems, and as a fluorescent protein label. Additionally, it demonstrates resistance to photodegradation, ensuring reliability in experimental settings.

Cat. No.

A43695

CAS No.

1357578-02-9

BD-Oligo

BD-Oligo is an oligomer-specific fluorescent chemical probe that selectively targets Aβ oligomer assemblies, distinguishing them from monomers and fibrils. Utilizing diversity-directed fluorescent library screening and advanced computational techniques, BD-Oligo enables real-time monitoring of oligomer formation during Aβ peptide fibrillogenesis. Additionally, this probe demonstrates blood-brain barrier permeability, allowing for in vivo staining of Aβ oligomers, making it a valuable tool for studying Alzheimer's disease and related neurodegenerative processes.

Cat. No.

A43696

CAS No.

129051-18-9

H2TMpyP-2 chloride

Synonyms: Tetrakis(2-N-methylpyridyl)porphine chloride

H2TMpyP-2 chloride is a potent photosensitizer that demonstrates strong absorption in the visible to near-infrared spectrum and exhibits a high singlet oxygen quantum yield. This compound is particularly useful in supramolecular nanosynthesis to enhance singlet oxygen production, photostability, and overall photosensitization, making it a valuable tool for photodynamic therapy applications. Additionally, the H2TMpyP-2 chloride has shown antibacterial effects against Escherichia coli and cytotoxic activity against A549 lung cancer cells, supporting its utility in both antimicrobial and anticancer research.

Cat. No.

A43697

CAS No.

62625-28-9

Brom0phenol blue sodium

Bromophenol blue sodium is a pH indicator that exhibits a color transition from yellow at pH 3.0 to blue at pH 4.6. This compound is widely utilized in molecular biology applications as a tracking dye for monitoring the progress of agarose and polyacrylamide gel electrophoresis. Its ability to indicate pH changes makes it a valuable tool in various biochemical assays and experiments.

Cat. No.

A43698

CAS No.

2968461-58-5

Gol-NTR

Gol-NTR is a Golgi-targetable probe that selectively activates upon interaction with Nitroreductase (NTR). This compound is designed for the visualization of acute lung injury (ALI) and its repair mechanisms, demonstrating high sensitivity with a detection limit of 54.8 ng/mL. Gol-NTR is particularly valuable in research applications aimed at monitoring and assessing cellular responses to sepsis-induced ALI, facilitating insights into injury and recovery processes within the Golgi apparatus.

Cat. No.

A43699

CAS No.

75806-94-9

3-(Dansylamino)phenylboronic acid

3-(Dansylamino)phenylboronic acid acts as a glucose detection agent through its ability to reversibly bind to glucose, forming stable complexes. This compound exhibits fluorescence properties, making it suitable for monitoring glucose levels in various biological samples. Its applications extend to research in diabetes, metabolism, and the development of glucose-sensitive materials.

Cat. No.

A43700

CAS No.

303727-66-4

FM1-84

Synonyms: Neurodye GH1-84

FM1-84 is a cell membrane fluorescent dye that serves as a valuable tool for visualizing synaptic vesicle recycling in neurons. Its lipophilic properties enable effective membrane association, enhancing fluorescence intensity with excitation at 510 nm and emission at 625 nm. This compound is essential for studies focusing on neuronal activity, membrane dynamics, and synaptic processes.

Cat. No.

A43702

CAS No.

1250963-36-0

CLR1501

CLR1501 is a fluorescently labeled analog of CLR1404, specifically designed for cancer cell imaging. This compound exhibits selective localization in cancer cells, allowing for enhanced visualization and study of tumor biology. CLR1501 can be utilized in various research applications, including cancer diagnostics and the assessment of tumor response to treatments.

Cat. No.

A43704

CAS No.

1372642-77-7

KMG-301AM

KMG-301AM is an acetoxymethyl ester of KMG-301 designed as a Mg2+ fluorescent probe targeting mitochondria. Upon accumulation within mitochondria, KMG-301AM is hydrolyzed to the active form, KMG-301, which is selective for Mg2+ detection in intact cells. This compound remains retained in the mitochondria due to the impermeable nature of the mitochondrial membrane, allowing it to reliably indicate variations in mitochondrial Mg2+ concentration and facilitate studies of Mg2+ transport across the mitochondrial membrane in cellular models.