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$0.00 Lipoxygenase
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Edaravone (MCI-186)
Catalog No. A11725 Edaravone is a free radical scavenger with diverse protective effects that inhibits production of reactive oxygen species, apoptosis and the lipoxygenase system. Learn More -
Tepoxalin
Catalog No. A12879 COX/5-LOX inhibitorTepoxalin is a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile Learn More -
Ginkgetin
Catalog No. A12061 Ginkgetin, a Biflavone from Ginko biloba leaves, inhibits cyclooxygenases-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells. Learn More -
AM 103
Catalog No. A21329 FLAP inhibitorAM 103 is a potent and selective FLAP inhibitor, with an IC50 value of 4.2 nM. Learn More -
MK 886
Catalog No. A13346 leukotriene biosynthesis inhibitorMK-886 is an inhibitor of leukotriene biosynthesis (IC50 = 3 nM in human polymorphonuclear leukocytes). Learn More -
AZD6642
Catalog No. A14400 FLAP inhibitorAZD6642 is an inhibitor of 5-Lipoxygenase Activating Protein (FLAP) for the treatment of inflammatory diseases. Learn More -
6,7-Dihydroxycoumarin
Catalog No. A14553 5-lipoxygenase inhibitorEsculetin, a phenolic compound, acts as a 5-LO (5-lipoxygenase, 5-LOX) inhibitor. Learn More -
MK-0591 (Quiflapon)
Catalog No. A15163 FLAP inhibitorMK-0591 is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor with an IC50 value of 1.6 nM in a FLAP binding assay. Learn More -
MK591
Catalog No. A15169 FLAP inhibitorMK591 is selective and specific inhibitor of 5-Lipoxygenase-activating protein (FLAP). Learn More -
Nordihydroguaiaretic acid
Catalog No. A15190 lipoxygenase inhibitorNordihydroguaiaretic acid is a natural phenolic compound isolated from the creosote bush Larrea divaricata, which has anti-tumor activities both in vitro and in vivo. Its analogs are in clinical development for use in refractory solid tumors. Learn More -
AM679
Catalog No. A14994 FLAP inhibitorAM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively. Learn More -
GSK2190915
Catalog No. A15818 FLAP inhibitorGSK2190915 is a potent FLAP(5-Lipoxygenase-activating protein) inhibitor with binding IC50 of 2.9 nM. Learn More -
Timegadine
Catalog No. A17108 COX and lipo-oxygenase inhibitorTimegadine, a new antiinflammatory agent, is found to be a potent, competitive inhibitor of cyclo-oxygenase (COX) and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates, and in washed rabbit platelets. Learn More
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