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$0.00 Farnesyl Transferase
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Lonafarnib (SCH66336)
Catalog No. A12328 FPTase inhibitorLonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Learn More -
L-778123 HCl
Catalog No. A15796 FPTase inhibitorL-778123 HCl is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and 98 nM in enzyme inhibition determination. Learn More -
Tipifarnib (Zarnestra)
Catalog No. A10935 FTase inhibitorTipifarnib (Zarnestra) is a farnesyltransferase inhibitor that inhibits the Ras kinase in a post translational modification step before the kinase pathway becomes hyperactive. Learn More -
FTI 277
Catalog No. A12368 FTase inhibitorFTI 276 is an inhibitor that inhibits farnesyltransferase (FTase) (IC50 = 0.5 nM). Inhibits H-Ras and K-Ras processing in whole cells (IC50 values are 0.1 and 10 μM respectively) and disrupts constitutive H-Ras-specific actvation of MAPK. Causes significant antiproliferative effects in human malignant glioma cells and many other tumor cell lines. Learn More -
LB42708
Catalog No. A14020 FTase inhibitorLB42708 is a potent, orally active and selective nonpeptidic farnesyltransferase inhibitor (FTase inhibitor). Learn More -
FTI-277 HCl
Catalog No. A14439 FTase InhibitorFTI-277 HCl is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling. Learn More
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