Farnesyl Transferase

6 Item(s)

per page

Set Descending Direction
  1. Lonafarnib (SCH66336)

    Catalog No. A12328
    Quick View
    FPTase inhibitor
    Lonafarnib (SCH 66336) is a selectively FPTase inhibitor for H-ras, K-ras-4B and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively. Learn More
  2. L-778123 HCl

    Catalog No. A15796
    Quick View
    FPTase inhibitor
    L-778123 HCl is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and 98 nM in enzyme inhibition determination. Learn More
  3. Tipifarnib (Zarnestra)

    Catalog No. A10935
    Quick View
    FTase inhibitor
    Tipifarnib (Zarnestra) is a farnesyltransferase inhibitor that inhibits the Ras kinase in a post translational modification step before the kinase pathway becomes hyperactive. Learn More
  4. FTI 277

    Catalog No. A12368
    Quick View
    FTase inhibitor
    FTI 276 is an inhibitor that inhibits farnesyltransferase (FTase) (IC50 = 0.5 nM). Inhibits H-Ras and K-Ras processing in whole cells (IC50 values are 0.1 and 10 μM respectively) and disrupts constitutive H-Ras-specific actvation of MAPK. Causes significant antiproliferative effects in human malignant glioma cells and many other tumor cell lines. Learn More
  5. LB42708

    Catalog No. A14020
    Quick View
    FTase inhibitor
    LB42708 is a potent, orally active and selective nonpeptidic farnesyltransferase inhibitor (FTase inhibitor). Learn More
  6. FTI-277 HCl

    Catalog No. A14439
    Quick View
    FTase Inhibitor
    FTI-277 HCl is an inhibitor of farnesyl transferase (FTase); a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling. Learn More

6 Item(s)

per page

Set Descending Direction
Rewards