NVP-BAW2881

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VEGFR inhibitor

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Catalog No. A12693

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
NVP-BAW2881 5mg A12693-5

Regular Price: $90.00

Special Price: $72.00

NVP-BAW2881 10mg A12693-10

Regular Price: $180.00

Special Price: $144.00

NVP-BAW2881 25mg A12693-25

Regular Price: $340.00

Special Price: $272.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

NVP-BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation.

NVP-BAW2881

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Chemical Information

Catalog Num A12693
Actions Inhibitor
M. Wt 424.1147
Formula C22H15F3N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 861875-60-7
Synonyms BAW2881, BAW-2881, BAW 2881, NVP-BAW-2881, NVP-BAW 2881
SMILES code O=C(NC1=CC(C(F)(F)F)=CC=C1)C2=CC=CC3=C2C=CC(OC4=CC=NC(N)=N4)=C3
Chemical Name 6-((2-aminopyrimidin-4-yl)oxy)-N-(3-(trifluoromethyl)phenyl)-1-naphthamide

Biological Activity

Description
NVP-BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation.
Targets
Target Value
TIE-2
hVEGFR2IC50: 9nM
C-Raf-1IC50: 24nM
B-RAFV599EIC50: 76nM
c-AblIC50: 99nM
mVEGF2IC50: 165nM
RETIC50: 410nM
hVEGFR3IC50: 420nM
hVEGFR1IC50: 820nM
c-KITIC50: 2.5μM

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